06/2015-04/2018 Postdoc, Orthopaedic Surgery, Duke University. Durham, NC, US

09/2010-06/2015 Ph.D., Biomedical Sciences, Texas A&M Health Science Center Dallas, TX, US

Research Interest

  • 1. Dissect the roles of marrow adipose tissue in osteonecrosis bone healing
  • 2. Investigate the chronic inflammation response in osteonecrosis, and seek for potential therapeutic target for preclinical treatment
  • 3. Explore the link between obesity, inflammation and osteoarthritis using transgenic animal models


Featured Publications LegendFeatured Publications

Notch signaling in postnatal joint chondrocytes, but not subchondral osteoblasts, is required for articular cartilage and joint maintenance.
Liu Z, Ren Y, Mirando AJ, Wang C, Zuscik MJ, O'Keefe RJ, Hilton MJ Osteoarthr. Cartil. 2015 Oct
Sclerostin antibody preserves the morphology and structure of osteocytes and blocks the severe skeletal deterioration after motor-complete spinal cord injury in rats.
Qin W, Li X, Peng Y, Harlow LM, Ren Y, Wu Y, Li J, Qin Y, Sun J, Zheng S, Brown T, Feng JQ, Ke HZ, Bauman WA, Cardozo CC J. Bone Miner. Res. 2015 May
Complete pulpodentin complex regeneration by modulating the stiffness of biomimetic matrix.
Qu T, Jing J, Ren Y, Ma C, Feng JQ, Yu Q, Liu X Acta Biomater 2015 Apr 16 60-70
Removal of SOST or blocking its product sclerostin rescues defects in the periodontitis mouse model.
Ren Y, Han X, Ho SP, Harris SE, Cao Z, Economides AN, Qin C, Ke H, Liu M, Feng JQ FASEB J. 2015 Mar
A novel way to statistically analyze morphologic changes in Dmp1-null osteocytes.
Ren Y, Lin S, Jing Y, Dechow PC, Feng JQ Connect. Tissue Res. 2014 Aug 55 Suppl 1 129-33
Induced ablation of Bmp1 and Tll1 produces osteogenesis imperfecta in mice.
Muir AM, Ren Y, Butz DH, Davis NA, Blank RD, Birk DE, Lee SJ, Rowe D, Feng JQ, Greenspan DS Hum. Mol. Genet. 2014 Jun 23 12 3085-101
BMP receptor 1A determines the cell fate of the postnatal growth plate.
Jing J, Ren Y, Zong Z, Liu C, Kamiya N, Mishina Y, Liu Y, Zhou X, Feng JQ Int. J. Biol. Sci. 2013 9 9 895-906
Genetic evidence for the vital function of Osterix in cementogenesis.
Cao Z, Zhang H, Zhou X, Han X, Ren Y, Gao T, Xiao Y, de Crombrugghe B, Somerman MJ, Feng JQ J. Bone Miner. Res. 2012 May 27 5 1080-92
Post-natal effect of overexpressed DKK1 on mandibular molar formation.
Han XL, Liu M, Voisey A, Ren YS, Kurimoto P, Gao T, Tefera L, Dechow P, Ke HZ, Feng JQ J. Dent. Res. 2011 Nov 90 11 1312-7
Inhibition of phosphatidylcholine-specific phospholipase C prevents bone marrow stromal cell senescence in vitro.
Sun C, Wang N, Huang J, Xin J, Peng F, Ren Y, Zhang S, Miao J J. Cell. Biochem. 2009 Oct 108 2 519-28

Honors & Awards

  • Michael Philip Jagger Research Award
    Duke University (2017)
  • ORS New Investigator Recognition Award
    Orthopaedic Research Society (2017)
  • ASBMR President's Award
    American Association of Bone and Mineral Research (2015)
  • AAA graduate student platform Award
    American Association of Anatomists (2013)
  • ICCBMT Young Investigator Award
    International Conference on the Chemistry and Biology of Mineralized Tissues (2013)
  • Hatton Award
    American Association for Dental Research (2012)

Professional Associations/Affiliations

  • Orthopaedic Research Society (2017)
  • American Association of Anatomists (2014)
  • American Association of Dental Research (2012)
  • American Society for Bone and Mineral Research (2011)