William Yarbrough Jr., M.D., is a Professor in the Department of Internal Medicine at UT Southwestern Medical Center and a member of the Division of Pulmonary and Critical Care Medicine. He is the National Program Director of Pulmonary, Critical Care, and Sleep for the VA Central Office, as well as Chief of the Pulmonary, Critical Care, and Sleep Section at the North Texas VA Health Care System in Dallas.

Originally from St. Louis, Dr. Yarbrough holds bachelor's degrees in chemistry and biology and mathematics,, a master's degree in immunopathology, and his medical degree from the University of Mississippi in Oxford. He then completed internal medicine residency training at the University of Mississippi, where he was Chief Resident. He completed advanced training through a fellowship in pulmonary diseases at UT Southwestern Medical Center.

Certified by the American Board of Internal Medicine in pulmonary and critical care medicine, Dr. Yarbrough joined the UT Southwestern faculty in 1988.

Dr. Yarbrough is a member of the American Thoracic Society, the Americna College of Chest Physicians, the American Academy of Sleep Medicine, and the American Federation for Clinical Research.

Dr. Yarbrough's clinical and research interests include sleep medicine, pulmonary care, and lung diseases. His findings have resulted in numerous peer-reviewed articles, lectures, and abstracts.


Medical School
University of Mississippi Medi (1981)

Research Interest

  • Immune defense in the lung
  • Intensive Care
  • Medical Ethics
  • Medical Informatics


Featured Publications LegendFeatured Publications

National Expansion of Sleep Telemedicine for Veterans: The TeleSleep Program.
Sarmiento KF, Folmer RL, Stepnowsky CJ, Whooley MA, Boudreau EA, Kuna ST, Atwood CW, Smith CJ, Yarbrough WC, J Clin Sleep Med 2019 Sep 15 9 1355-1364
Outcomes comparison in patients admitted to low complexity rural and urban intensive care units in the Veterans Health Administration.
O'Shea AMJ, Fortis S, Vaughan Sarrazin M, Moeckli J, Yarbrough WC, Schacht Reisinger H J Crit Care 2019 Feb 49 64-69
COPD and Rural Health: A Dialogue on the National Action Plan.
Moore P, Atkins GT, Cramb S, Croft JB, Davis L, Dolor RJ, Doyle D, Elehwany M, James C, Knudson A, Linnell J, Mannino D, Rommes JM, Sood A, Stockton E, Weissman DN, Witte M, Wyatt E, Yarbrough WC, Yawn BP, Johnson L, Morris T, Kiley JP, Ammary-Risch NJ, Punturieri A J Rural Health 2019 Jan
Right heart, arterial, and central venous catheterization all identify patients at increased risk of in-hospital mortality.
Sharma, S., W.C. Yarbrough and A.K. Pierce Texas Thoracic Society April 1997
Surfactant alters fluidity and proliferation in both T cells and human lung fibroblasts.
Yarbrough, W.C. and J.C. Weissler J. of Investigative Medicine 1995 43:338A
Surfactant alters membrane fluidity in both T cells and lung fibroblasts.
Yarbrough W.C. and J.C. Weissler Am. J. Resp. Crit. Care Med. 1995 150:A360
Surfactant alters lymphocyte membrane fluidity during suppression.
Yarbrough, W.C., C. Mendelson, M. Levi and J.C. Weissler Clin. Res. 1994 42:189A
Suppression of lymphocyte function by surfactant is associated with membrane rigidity.
Yarbrough, W.C., C. Mendelson, M. Levi and J.C. Weissler Am. J. Resp. Crit. Care Med. 1994 149A:265

Professional Associations/Affiliations

  • American Association for the Advancement of Science
  • American College of Chest Physicians
  • American College of Physicians
  • American Federation for Clinical Research
  • American Thoracic Society