Amin Amin, M.D. Assistant Professor School Medical School Department Internal Medicine You have reached the Academic Profile. For more information on the doctor and patient care, please visit the clinical profile. Biography Amin Amin, M.D., is an Assistant Professor in the Department of Internal Medicine at UT Southwestern Medical Center and a member of its Division of Digestive and Liver Diseases. He specializes in general gastroenterology, general hepatology and obesity medicine with a focus on metabolic dysfunction-associated steatotic liver disease (MASLD). Dr. Amin earned his medical degree with honors from the University of Leicester School of Medicine in England. He completed postdoctoral training in metabolic science and clinical residency training at University Hospitals Birmingham in England. He received advanced training in immune-metabolism and adipocyte biology at the University of California San Francisco, before joining UT Southwestern's Physician Scientist Training Program (PSTP). He received internal medicine residency training and fellowship training in gastroenterology and hepatology at UT Southwestern, with an additional focus on obesity medicine. Certified by the Royal College of Surgeons of England and the American Board of Internal Medicine in gastroenterology and obesity medicine, Dr. Amin joined the UT Southwestern faculty in 2024. He brings a wealth of experience spanning scientific, medical, and surgical disciplines from both sides of the Atlantic. Dr. Amin stands at the forefront of liver health research, contributing significantly to the understanding and treatment of metabolic liver diseases. His groundbreaking research focuses on improving liver transplant success by reducing excess fat in livers, making them less susceptible to ischemia. Utilizing his expertise in quantitative hepatic metabolism and a refined platform of rodent normothermic machine perfusion, he employs carbon-13 tracers to investigate metabolic aberrations in MASLD. His goal is to develop new treatments for this growing disease, offering hope to those suffering and those on the transplant waitlist. Education Medical School University of Leicester, England (2010) Residency UT Southwestern Medical Center (2020), Internal Medicine Fellowship UT Southwestern Medical Center (2023), Gastroenterology Research Interest Biological NMR and MS In Vivo and Ex Vivo isotope tracer techniques Intermediary metabolism of obesity and diabetes Metabolic mechanisms of disease Regulation of carbohydrate and lipid metabolism in liver Transplantation, Ischemia, Reperfusion Publications Specific Macronutrients Exert Unique Influences on the Adipose-Liver Axis to Promote Hepatic Steatosis in Mice Duwaerts CC, Amin AM, Siao K, Her C, Fitch M, Beysen C, Turner SM, Goodsell A, Baron JL, Grenert JP, Cho SJ, Maher JJ CMGH 2017 Sep 4 223-236 Inhibition of SNAT2 by metabolic acidosis enhances proteolysis in skeletal muscle Evans K, Nasim Z, Brown J, Clapp E, Amin A, Yang B, Herbert TP, Bevington A Journal of the American Society of Nephrology 2008 Nov 19 2119-2129 Results 1-2 of 2 1 Professional Associations/Affiliations American Association for the Study of Liver Disease American College of Gastroenterology American Gastroenterology Association The Obesity Society