Ru-Feng Wu, M.D., Ph.D., is an Assistant Professor in the Department of Internal Medicine at UT Southwestern Medical Center and a member of the Division of Pulmonary and Critical Care Medicine

Originally from China, Dr. Wu earned his medical degree and a master's degree in toxicology at China Medical University. He earned his doctorate in biochemistry at Kagawa Medical School in Japan. He completed postdoctoral fellowships in biochemistry and internal medicine at UT Southwestern Medical Center.

Dr. Wu joined the UT Southwestern faculty in 2008.


Medical School
China Medical University - Chi (1984)
Graduate School
Kagawa Medical School - ? (1995)

Research Interest

  • Cell signal transduction
  • HIV Tat and Endothelial Cell Dysfunction
  • Oxidant signaling pathways


Featured Publications LegendFeatured Publications

Nox4-derived H2O2 mediates endoplasmic reticulum signaling through local Ras activation
Wu RF, Ma Z and Terada LS Mol Cell Biol July 2010 14 (30) 3553-3568
Ras and Nox: linked signaling networks?
Wu RF and Terada LS Free Radical Biology & Medicine November 2009 47 (9) 1278-81
HIV1 Tat activates dual Nox pathways leading to independent activation of ERK and JNK MAP kinases.
Wu RF, Ma Z, Myers DP, et al. JOURNAL OF BIOLOGICAL CHEMISTRY December 2007 282 (52) 37412-37419
Oxidative modification of protein tyrosine phosphatases.
Wu, R.F., and Terada, L.S., Sci STKE April 2006 2006 (332) P12
Subcellular targeting of oxidants during endothelial cell migration
Wu, R.F., Y.C. Xu, Z. Ma, F.E. Nwariaku, G.A, Sarosi, and L.S. Terada J. Cell Biol December 2005 171(5) 893-904

Honors & Awards

  • Scholar in Scientific Research
    ministry of education, science and culture, Japan (1991)