Dr. Chi grew up in Beijing China. He attended undergraduate study at Peking University and medical school at Peking Union Medical College. He later joined Drs. Valina and Ted Dawson’s laboratory at the Johns Hopkins University School of Medicine, where he studied the molecular mechanisms of neuroprotection and neurodevelopment. His Ph.D. works were published in high-profile journals including Cell, Development Cell, Cell reports, Nature Medicine, and Proceedings of the National Academy of Sciences. Dr. Chi subsequently trained in anatomic and clinical pathology residency at Indiana University School of Medicine, and gastrointestinal and liver pathology fellowship at Cedars Sinai Medical Center. He joined the faculty as an Assistant Professor at UTSW in July 2018.

Dr. Chi’s current research interests include clinicopathological, immunohistochemical, and molecular characterization of gastrointestinal, pancreatic, and liver neoplasm as well as inflammatory diseases. He also actively engages in collaborative research projects with basic scientists interested in gastrointestinal and pancreatic diseases. Dr. Chi currently serves as coinvestigators in multiple NIH funded studies and always looks forward to more collaborating opportunities both inside and outside the campus.


Other Post Graduate Training
John Hopkins University School of Medicine
Medical School
Peking Union Medical College (2003)
Graduate School
Johns Hopkins University School of Medicine (2009)
Johns Hopkins Hospital (2013), Post Doctoral
Indiana University School of Medicine (2017), Pathology
Cedars Sinai Medical Center (2018), Gastrointestinal & Liver Pathology

Research Interest

  • Clinicopathologic characterization of gastrointestinal tract inflammatory diseases such as inflammatory bowel disease and microscopic colitis.
  • Clinicopathologic characterization of gastrointestinal tract, liver, and pancreatic tumors, with a current emphasis on esophageal squamous cell carcinoma and pancreatic ductal adenocarcinoma.


Featured Publications LegendFeatured Publications

Noninvasive monitoring of hepatic glutathione depletion through fluorescence imaging and blood testing.
Jiang X, Zhou Q, Du B, Li S, Huang Y, Chi Z, Lee WM, Yu M, Zheng J, Sci Adv 2021 Feb 7 8
The AAA?+?ATPase Thorase is neuroprotective against ischemic injury.
Zhang J, Yang J, Wang H, Sherbini O, Keuss MJ, Umanah GK, Pai EL, Chi Z, Paldanius KM, He W, Wang H, Andrabi SA, Dawson TM, Dawson VL J. Cereb. Blood Flow Metab. 2018 Jan 271678X18769770
as a Key Mediator of Neuronal Cell Death.
Zhang J, Wang H, Sherbini O, Ling-Lin Pai E, Kang SU, Kwon JS, Yang J, He W, Wang H, Eacker SM, Chi Z, Mao X, Xu J, Jiang H, Andrabi SA, Dawson TM, Dawson VL eNeuro 2016 Sep-Oct 3 5
Cultured networks of excitatory projection neurons and inhibitory interneurons for studying human cortical neurotoxicity.
Xu JC, Fan J, Wang X, Eacker SM, Kam TI, Chen L, Yin X, Zhu J, Chi Z, Jiang H, Chen R, Dawson TM, Dawson VL Sci Transl Med 2016 Apr 8 333 333ra48
Neonatal stroke in mice causes long-term changes in neuronal Notch-2 expression that may contribute to prolonged injury.
Albéri L, Chi Z, Kadam SD, Mulholland JD, Dawson VL, Gaiano N, Comi AM Stroke 2010 Oct 41 10 Suppl S64-71
BRI3 associates with SCG10 and attenuates NGF-induced neurite outgrowth in PC12 cells.
Gong Y, Wu J, Qiang H, Liu B, Chi Z, Chen T, Yin B, Peng X, Yuan J BMB Rep 2008 Apr 41 4 287-93