Dr. Jiang is a molecular biologist with more than 10-years’ experience studying protein function, structure, and function-structure relationship utilizing a combination of biochemical, molecular, biophysical, and structural techniques. She received her Ph.D. degree in Biochemistry and Molecular Biology from Wayne State University in 2009. After graduation, she worked as a postdoctoral scholar at UCLA. After three years of postdoctoral training program at UCLA, she moved to Colorado with her family. She was very fortunate to become a full-time mom to care for my newborn daughter from 2013-2015. In 2015 she joined Dr. Sucharov’s lab at CU-Denver where she studied the cellular mechanisms involved in pediatric heart failure. During this time, she refined her career objectives and decided to focus on cardiovascular translational research. In 2018, she joined Dr. Pradeep Mammen’s lab at UT-Southwestern Medical Center as an assistant instructor. Currently, her research focuses on identification of cellular mechanism in patients with Duchenne Muscular Dystrophy, and correlation between clinical and molecular phenotypes in this population.
- Cardiac Differentiation
- Cardiac Hypertrophy
- Epicardial Cells
- Epithelial to Mesenchymal Transition
- Optimization of phenol-chloroform RNA extraction.
- Toni LS, Garcia AM, Jeffrey DA, Jiang X, Stauffer BL, Miyamoto SD, Sucharov CC MethodsX 2018 5 599-608
- Exosomes from pediatric dilated cardiomyopathy patients modulate a pathological response in cardiomyocytes.
- Jiang X, Sucharov J, Stauffer BL, Miyamoto SD, Sucharov CC Am. J. Physiol. Heart Circ. Physiol. 2017 Apr 312 4 H818-H826
- Conserved cysteine residues determine substrate specificity in a novel As(III) S-adenosylmethionine methyltransferase from Aspergillus fumigatus.
- Chen J, Li J, Jiang X, Rosen BP Mol. Microbiol. 2017 Jan
- Functional identification and characterization of sodium binding sites in Na symporters.
- Loo DD, Jiang X, Gorraitz E, Hirayama BA, Wright EM Proc. Natl. Acad. Sci. U.S.A. 2013 Nov 110 47 E4557-66
- The importance of being aromatic: p interactions in sodium symporters.
- Jiang X, Loo DD, Hirayama BA, Wright EM Biochemistry 2012 Nov 51 47 9480-7
- Trivalent arsenicals and glucose use different translocation pathways in mammalian GLUT1.
- Jiang X, McDermott JR, Ajees AA, Rosen BP, Liu Z Metallomics 2010 Mar 2 3 211-9
- Pentavalent methylated arsenicals are substrates of human AQP9.
- McDermott JR, Jiang X, Beene LC, Rosen BP, Liu Z Biometals 2010 Feb 23 1 119-27
- Mammalian glucose permease GLUT1 facilitates transport of arsenic trioxide and methylarsonous acid.
- Liu Z, Sanchez MA, Jiang X, Boles E, Landfear SM, Rosen BP Biochem. Biophys. Res. Commun. 2006 Dec 351 2 424-30
Metalloid Transport Systems. In Biological Chemistry of Arsenic, Antimony and Bismuth
Hsueh-Liang Fu, Xuan Jiang, and B.P. Rosen (2010). Chichester, UK, John Wiley & Sons, Ltd.
- American Heart Association (2015)
- International Society for Heart Research (ISHR) (2015)