Dr. Kathleen S. Wilson is the Director of the Cytogenomic Microarray Analysis (CMA) laboratory in the Genetic Diagnostics Laboratories. She established the first CMA Laboratory for patient diagnostics in North Texas in 2008, bringing this technologically advanced form of high resolution chromosome analysis for clinical care to U.T. Southwestern and the North Texas region. She completed her undergraduate education at Amherst College and graduated with honors in 1986. She received her medical degree in 1991 from The University of Texas Southwestern Medical Center at Dallas. She subsequently completed pathology residency and genetics fellowship training also at UT Southwestern. 

Dr. Wilson is a faculty member in the Department of Pathology and the McDermott (Genetics) Center for Human Growth and Development. She is board-certied by the American Board of Pathology (ABP) in Clinical Pathology and the American Board of Medical Genetics (ABMG) in Clinical Cytogenetics. She is also a fellow of the College of American Pathologists (CAP) and the American College of Medical Genetics (ACMG). 

She has served on the Cytogenetics Resource Committee (CyRC) of the CAP and ACMG for over a decade and was involved in setting national policy for cytogenetics and molecular cytogenomics by developing accreditation guidelines and issuing proficiency testing. She has served as chair of the Economics of Genetic Services Committee for ACMG and has also been an active participant nationally in policy related to reimbursement for high complexity genetic testing.  She is currently involved in multiple medical school administrative and educational activities in her roles as Chair of the UT Southwestern Medical School Admissions Committee and Co-Director of the Medical Student Genetics Course.

Dr. Wilson’s interest and experience in molecular genetics and genomics have been longstanding with recent publications in The Journal of Pediatric Hematology Oncology and Pediatric and Developmental Pathology, and book chapters in Abeloff: Clinical Oncology, 4th ed., Clinical Laboratory Hematology, 3rd ed. and Rosenberg’s Molecular and Genetic Basis of Neurological and Psychiatric Disease, 5th ed. 

Dr. Wilson has won teaching awards and has been actively involved in the teaching and mentorship of medical and graduate students, house staff, and junior faculty for over twenty-five years.


Medical School
UT Southwestern Medical School (1991)
UT Southwestern Medical Center (1992), Pathology
UT Southwestern Medical Center (1994), Pathology
UT Southwestern Medical Center (1995), Hematopathology
UT Southwestern Medical Center (1997), Cytogenetics

Research Interest

  • My research interests are focused on the clinical utilization of multiple genetic diagnostic technologies (next generation sequencing, cytogenomic microarray analysis, fluorescence in situ hybridization and conventional cytogenetics) in an integrated approach to elucidate the pathogenetic events of both constitutional and acquired (neoplastic) disorders.


Featured Publications LegendFeatured Publications

High-resolution array CGH identifies common mechanisms that drive embryonal rhabdomyosarcoma pathogenesis.
Paulson V, Chandler G, Rakheja D, Galindo R, Wilson K, Amatruda JF, Cameron S. Genes Chromosom Cancer 2011 50 397-408.
A bcr3/short form PML/RARα transcript in an acute promyelocytic leukemia resulted from a derivative chromosome 17 due to submicroscopic insertion of PML gene into RARα locus.
Wang H-Y, Ding J, Vasef MA, Wilson KS. Am J Clin Path 2009 131 64-71.
An extranodal nasal natural killer/T-cell lymphooma with isochromosome 7q10 as the sole cytogenetic aberration was initially diagnosed via bone marrow biopsy.
Wang H-Y, Wilson KS, McKenna RW, Karandikar N, Xu Y. Arch Pathol Lab Med 2007 131 1709-1714.
Immunophenotypic identification of acute myeloid leukemia with monocytic differentiation.
Xu Y, McKenna RW, Wilson KS, Karandikar NJ, Schultz RA, Kroft SH. Leukemia 2006 20 1321-1324.
HER-2 fluorescence in situ hybridization: results from the survey program of the College of American Pathologists.
Persons DL, Tubbs RR, Cooley LD, Dewald GW, Dowling PK, Du E, Mascarello JT, Rao KW, Wilson KS, Wolff DJ, Habegger-Vance G. Arch Pathol Lab Med 2006 130 325-331.
Primary effusion lymphomas (PEL) exhibit complex and recurrent cytogenetic abnormalities.
Wilson KS, McKenna RW, Kroft SH, Dawson DB, Ansari Q, Schneider NR. Br J Haematol 2002 116 113-121.
Chronic myelogenous leukemia [review].
Willis MS and Wilson KS. Lab Med 2002 33 203-207.

Honors & Awards

  • Doximity Recognition
    Top M.D. by Consumers Checkbook (2017)
  • Outstanding Teacher in Genetics: Pre-Clinical Teaching Award
    UT Southwestern Class of 2015 (2012)
  • Guide to America's Top Pathologists
    Consumers' Research Council of America (2007-present) (2007)
  • Outstanding Teacher in Pathology
    UT Southwestern Class of 2009 (2007)
  • Small Group Teaching Award in Pathology
    UT Southwestern Class of 2009 (2007)
  • Favorite Teacher Recognition in Pathology
    UT Southwestern Class of 2007 (2005)
  • Guide to America's Top Physicians
    Consumers' Research Council of America (2004-present) (2004)
  • Amherst College: Graduation with Honors
    B.A., magna cum laude (1986)
  • Aston L. Clarke Research Fellowship
    UT Southwestern Medical Center at Dallas (1985)

Professional Associations/Affiliations

  • American College of Medical Genetics (2002)
  • College of American Pathologists (1993)
  • American Medical Association (1991)
  • Dallas County Medical Society (1991)
  • Texas Medical Association (1991)