Madhuri Sopirala, M.D.

Madhuri Sopirala, M.D., M.P.H. is an Associate Professor in the Department of Internal Medicine at UT Southwestern Medical Center, and a member of its Division of Infectious Diseases and Geographic Medicine. She serves as Director of Infection Prevention at Parkland Health and Hospital System. 

I feel honored to be a member of the UTSW and Parkland medical staff and would cherish the opportunity to serve as a member of Medical Executive Committee at Parkland.

Dr. Sopirala attended medical school at Sri Venkatesvara Medical College in Andhra Pradesh, India. She received internal medicine residency training at Mount Carmel Medical Center in Columbus, Ohio, and completed advanced training through an infectious diseases fellowship at Ohio State University Medical Center, where she also earned a master's in public health for clinical investigation and epidemiology.

Board certified in internal medicine and in infectious diseases, she joined the UT Southwestern faculty in 2017 as the Chief of Infection Prevention at the VA North Texas Healthcare System. Previously, she served for five years as the Associate Chief of the Department of Clinical Epidemiology/Infection Prevention and Control at The Ohio State University Medical Center, and for six years as the Chief of IPC at the University of Cincinnati Healthcare System, where she successfully led system-wide performance improvement in prevention of hospital-acquired infections (HAI), with particular expertise in central line associated blood stream infections. At both institutions, she implemented her signature program – Infection Control Link Nurse Program – which brought multiple disciplines together in infection prevention efforts for sustained improvements.

Dr. Sopirala has received formal training and earned certifications in Lean Systems Quality Improvement and has mentored numerous fellows, residents and medical students throughout her career. Her work with the trainees and work in HAI prevention has resulted in multiple peer reviewed publications. She is recognized as a leader in the field by national organizations and serves on the editorial boards for several reputed journals. As a result of her work in HAI reduction, Dr. Sopirala received the University of Cincinnati's IMPACT award, granted to the most impactful physician in the health system. She was also awarded a New Investigator award at VAMC-North Texas for a novel study focusing on the epidemiology of multidrug resistant Gram-negative colonization and infection.

Dr. Sopirala's research is focused on healthcare associated infections and multidrug resistant Gram-negative organisms.

Medical School

Sri Venkateswara University (1999)

Residency

Mount Carmel Medical Center (2005), Internal Medicine

Fellowship

Ohio State University Hospital (2007), Infectious Diseases

Graduate School

The Ohio State University College of Public Health (2009)

Other Post Graduate Training

Ohio State University College of Public Health (2009)

• Healthcare-Acquired Infections
• Multidrug-resistant Gram-negative organisms
• Process Improvement

Central Line-Associated Bloodstream Infection Misclassifications - Rethinking the Centers for Disease Control and Prevention's Central Line-Associated Bloodstream Infection Definition and Its Implications

Sopirala MM, Estelle CD, Houston L Critical care medicine 2024 Mar 52 357-361

Investigation of the first reported outbreak of New Delhi metallo-β-lactamase-1-producing Pseudomonas aeruginosa in Texas

Sopirala MM, Hartless K, Reid S, Christie-Smith A, Fiveash J, Badejogbin A, Psenicka AO Antimicrobial Stewardship and Healthcare Epidemiology 2024 Jan 3

Effect of serious infectious threat response initiative (SITRI) during the coronavirus disease 2019 (COVID-19) pandemic at the Veterans Affairs North Texas Health Care System

Sopirala M, Hartless K, Reid S, Christie-Smith A, Fiveash J, Badejogbin A, Omoola I, Psenicka AO, Jandarov R, Kazadi I, Barriento R American Journal of Infection Control 2023 Sep 51 980-987

Build upon basics: An intervention utilizing safety huddles to achieve near-zero incidence of catheter associated urinary tract infection at a department of Veterans Affairs long-term care facility

Fiveash JM, Smith ML, Moore AK, Jandarov R, Sopirala MM American Journal of Infection Control 2021 Nov 49 1419-1422

Predisposition of COVID-19 patients to secondary infections: set in stone or subject to change?

Sopirala MM Current Opinion in Infectious Diseases 2021 Aug 34 357-364

Out of sight—out of mind: Impact of cascade reporting on antimicrobial usage

Liao S, Rhodes J, Jandarov R, DeVore Z, Sopirala MM Open Forum Infectious Diseases 2020 Feb 7

Impact of a change in surveillance definition on performance assessment of a catheter-associated urinary tract infection prevention program at a tertiary care medical center

Sopirala MM, Syed A, Jandarov R, Lewis M American Journal of Infection Control 2018 Jul 46 743-746

Effect of automated ultraviolet C–emitting device on decontamination of hospital rooms with and without real-time observation of terminal room disinfection

Penno K, Jandarov RA, Sopirala MM American Journal of Infection Control 2017 Nov 45 1208-1213

Does the Centers for Disease Control and Prevention's Ventilator-Associated Event Definition Unintentionally Contradict Its Antimicrobial Stewardship Initiative?

Sopirala MM Clinical Infectious Diseases 2017 Oct 65 1248-1249

Infection control link nurse program: An interdisciplinary approach in targeting health care-acquired infection

Sopirala MM, Yahle-Dunbar L, Smyer J, Wellington L, Dickman J, Zikri N, Martin J, Kulich P, Taylor D, Mekhjian H, Nash M, Mansfield J, Pancholi P, Howard M, Chase L, Brown S, Kipp K, Lefeld K, Myers A, Pan X, Mangino JE American Journal of Infection Control 2014 Apr 42 353-359

 Featured Books

Lung Abscesses and Pleural Abscesses. In Infectious Diseases Third Edition

Sopirala MM, Mangino, JE (2009). United Kingdom, Elsevier

Tuberculosis. In Treatment Strategies for Common Medical Problems Second Edition

Sopirala MM, Mangino, JE. (2009). United Kingdom, Elsevier

• Fellow
  Infectious Diseases Society of America (2016)
• IMPACT award
  University of Cincinnati Medical Center (2015)
• Fellow
  American College of Physicians (2012)
• Honorable Mention, SHEA-APIC Partnership in Prevention Award
  Fifth Decennial International Conference on Healthcare-Associated Infections (2010)

• American College of Physicians
• Infectious Diseases Society of America
• Society for Healthcare Epidemiology of America
• Society of Healthcare Epidemiology Long Term Care Interest Group