Dimitrios Angelis, MD, is an Associate Professor of Pediatrics, with specialization in Neonatal-Perinatal Medicine, at the University of Texas, Southwestern Medical Center (UTSW). He is a graduate from the University of Athens in Greece. He completed his fellowship in Neonatal-Perinatal medicine at St. Christopher's Hospital for Children, Philadelphia (Drexel University College of Medicine) in 2014. His research involved the effect of Src Kinase as a modulator of Hypoxia-Ischemia in a neonatal swine model. He joined UTSW in 2019. His current research interests include (a) understanding the pathophysiology of brain after hypoxia-ischemia related to nitric oxide, (b) effects of acetaminophen in the neonatal brain, (c) prevention of intraventricular hemorrhage (IVH) in extremely preterm newborns (d) vein of Galen arteriovenous malformation, management of early heart failure and (e) zinc and neonatal brain.


Medical School
University of Athens School of Health Sciences, Greece (2003)
Monmouth Medical Center (2011), Pediatrics
St Christopher's Hospital for Children (2014), Neonatal-perinatal Medicine

Research Interest

  • Neonatal brain injury
  • Zinc and neonatal brain


Featured Publications LegendFeatured Publications

Human Parechovirus (HPeV) infections: clinical presentations, patterns, and evolution of neonatal brain injury.
Oren MS, Clarke RL, Price M, Thomas JM, Machie M, Dolce AM, Chalak LF, Angelis D, J Perinatol 2023 Dec
Hyperglycemia and prematurity: a narrative review.
Angelis D, Jaleel MA, Brion LP, Pediatr Res 2023 Apr
Implementation of morbidity and mortality conference in a community hospital NICU and narrative review.
Chan C, Pazandak C, Angelis D, Front Pediatr 2023 11 1321296
Developmental changes of the fetal and neonatal thyroid gland and functional consequences on the cardiovascular system.
Kotsopoulou I, Vyas AK, Cory MJ, Chan CS, Jagarapu J, Gill S, Mudduluru M, Angelis D, J Perinatol 2022 Dec 42 12 1576-1586
Vein of Galen aneurysmal malformation: rationalizing medical management of neonatal heart failure.
Cory MJ, Durand P, Sillero R, Morin L, Savani R, Chalak L, Angelis D, Pediatr Res 2022 Apr
Acetaminophen and the developing brain: A critical review of the evidence.
Angelis D, Chalak L, Early Hum Dev 2021 Jun 105411
Part III. Neuronal biochemical effects of acetaminophen and neurodevelopmental outcomes: Friend or foe?
Angelis D, León RL, Chalak L, Early Hum Dev 2021 Jun 105408
Part I. Mechanisms of actions and metabolism of acetaminophen related to the neonatal brain.
Angelis D, Savani RC, Jagarapu J, Hu J, Wan-Huen P, Chalak L, Early Hum Dev 2021 Jun 105406
Part II. Acetaminophen and closure of ductus arteriosus in the newborns: Mechanisms of action, clinical studies, safety and efficacy.
Angelis D, Jagarapu J, Wan-Huen P, Savani RC, Jaleel M, Early Hum Dev 2021 Jun 105407
Nitric oxide and the brain. Part 2: Effects following neonatal brain injury-friend or foe?
Angelis D, Savani R, Chalak L, Pediatr Res 2021 Mar 89 4 746-752

Honors & Awards

  • Dean's Inpatient Medical Care Award and Outstanding Clinical Care Award
    Texas Tech University (2017)
  • The Angelo M. DiGeorge Teaching Award
    St. Christopher's Hospital for Children (2014)

Professional Associations/Affiliations

  • American Academy of Pediatrics (2008)
  • American Academy of Pediatrics, Perinatal Section (2011)
  • General Medical Council (London, UK) (2016-2017)
  • Hellenic Medical Society (Athens, Greece) (2003)
  • Society for Pediatric Research (2012)
  • Society of Critical Care Medicine (2009-2011)
  • Texas Pediatric Society (2014)