Charles L. White, III, M.D., is Professor of Pathology and holds the Nancy R. McCune Distinguished Chair in Alzheimer Disease Research. He has been the Director of Neuropathology at UT Southwestern since completing his residency and fellowship training in anatomic pathology and neuropathology at Johns Hopkins in 1983.

Dr. White’s clinical and research interests focus on neurodegenerative brain disorders. He has been the director of the Neuropathology Core of the UT Southwestern Alzheimer Disease Research Center since its inception in 1988. He also directs the Winspear Family Special Center for Research on the Neuropathology of Alzheimer's Disease, established at UT Southwestern in 2002 by a generous gift from the Bill and Margot Winspear Family.

Dr. White is the Training Director for the Neuropathology Fellowship program at UT Southwestern, an ACGME-accredited, 2-year training program. Twenty-two trainees have completed the program and become board certified by the American Board of Pathology in the subspecialty of Neuropathology.

Dr. White is past president of the American Association of Neuropathologists, the national professional organization for neuropathologists in the US.  In 2020, he received its annual Award for Meritorious Contributions to Neuropathology.


Medical School
University of Arizona College of Med. (1978)
Johns Hopkins Hospital (1979), Pathology
Johns Hopkins Hospital (1981), Pathology
Johns Hopkins University School of Medicine (1983), Neuropathology

Research Interest

  • Alzheimer disease
  • Digital and quantitative neuropathology
  • Forensic neuropathology
  • Immunohistochemistry
  • Neurodegenerative disorders
  • Tissue microarray technology


Featured Publications LegendFeatured Publications

Early Selective Vulnerability of the CA2 Hippocampal Subfield in Primary Age-Related Tauopathy.
Walker JM, Richardson TE, Farrell K, Iida MA, Foong C, Shang P, Attems J, Ayalon G, Beach TG, Bigio EH, Budson A, Cairns NJ, Corrada M, Cortes E, Dickson DW, Fischer P, Flanagan ME, Franklin E, Gearing M, Glass J, Hansen LA, Haroutunuan V, Hof PR, Honig L, Kawas C, Keene CD, Kofler J, Kovacs GG, Lee EB, Lutz MI, Mao Q, Masliah E, McKee AC, McMillan CT, Mesulam MM, Murray M, Nelson PT, Perrin R, Pham T, Poon W, Purohit DP, Rissman RA, Sakai K, Sano M, Schneider JA, Stein TD, Teich AF, Trojanowski JQ, Troncoso JC, Vonsattel JP, Weintraub S, Wolk DA, Woltjer RL, Yamada M, Yu L, White CL, Crary JF, J Neuropathol Exp Neurol 2020 Dec
In vivo distribution of a-synuclein in multiple tissues and biofluids in Parkinson disease.
Chahine LM, Beach TG, Brumm MC, Adler CH, Coffey CS, Mosovsky S, Caspell-Garcia C, Serrano GE, Munoz DG, White CL, Crary JF, Jennings D, Taylor P, Foroud T, Arnedo V, Kopil CM, Riley L, Dave KD, Mollenhauer B, Neurology 2020 Sep 95 9 e1267-e1284
Aggressive FUS-Mutant Motor Neuron Disease Without Profound Spinal Cord Pathology.
Wongworawat YC, Liu YA, Raghavan R, White CL, Dietz R, Zuppan C, Rosenfeld J, J. Neuropathol. Exp. Neurol. 2020 Apr 79 4 365-369

Honors & Awards

  • Award for Meritorious Contributions to Neuropathology, American Association of Neuropathologists
  • President, American Association of Neuropathologists
  • Best Doctors in America, 2003-2020
  • Manuscript of the Year Award, ASCP
  • Phi Beta Kappa

Professional Associations/Affiliations

  • American Association of Neuropathologists (1983)
  • American Society for Clinical Pathology (2001)
  • American Society for Investigative Pathology (1984)
  • Digital Pathology Association (2015)
  • Society for Neuroscience (1990)
  • The Histochemical Society (1984)
  • United States and Canadian Academy of Pathology (1981)