Parastoo Sabaeifard, Ph.D. Titles and Appointments Assistant Professor School Medical School Department Pediatrics Biography Dr. Parastoo Sabaeifard earned her Ph.D. in Biology-Microbiology from Alzahra University in Tehran, Iran, in collaboration with the University of Navarra in Spain. Her doctoral and postdoctoral training established expertise in antibiotic resistance, bacterial biofilms, drug delivery using polymeric nanoparticles, and immune-oncology model development. Dr. Sabaeifard is currently an assistant professor at UT Southwestern Medical Center, where her multidisciplinary work focuses on the interplay between the gut microbiota, host immune responses, and tumor immunity, as well as the development of preclinical humanized mouse models for translational immuno-oncology studies. In addition to her scientific accomplishments, Dr. Sabaeifard is deeply engaged in mentorship and scientific training, having supervised graduate students, postdoctoral fellows, and clinical researchers. Outside of research, she enjoys exploring new cultures through travel and food, reading, cooking, and spending time with family and friends. Research Interest Antibiotic Resistance Cancer immunotherapy Gut Microbiota Host immune anti-tumor response Publications Featured Publications Susceptible bacteria survive antibiotic treatment in the mammalian gastrointestinal tract without evolving resistance. Rodrigues M, Sabaeifard P, Yildiz MS, Coughlin L, Ahmed S, Behrendt C, Wang X, Monogue M, Kim J, Gan S, Zhan X, Filkins L, Williams NS, Hooper LV, Koh AY, Toprak E, bioRxiv 2023 Jan Optimization of tetrazolium salt assay for Pseudomonas aeruginosa biofilm using microtiter plate method. Sabaeifard P, Abdi-Ali A, Soudi MR, Dinarvand R, J Microbiol Methods 2014 Oct 105 134-40 Identifying Microbiota and Immune Host Factors Associated With Bleeding Risk in Children With Immune Thrombocytopenia. Saini S, Sabaeifard P, Coughlin L, Poulides N, Gan S, Zhan X, Dang M, Koh AY, Zia A, Am J Hematol 2025 Jun 100 6 1090-1093 Wnt16 Promotes Vascular Smooth Muscle Contractile Phenotype and Function via Taz (Wwtr1) Activation in Male LDLR-/- Mice. Behrmann A, Zhong D, Li L, Xie S, Mead M, Sabaeifard P, Goodarzi M, Lemoff A, Kozlitina J, Towler DA, Endocrinology 2023 Dec 165 2 PTH/PTHrP Receptor Signaling Restricts Arterial Fibrosis in Diabetic LDLR-/- Mice by Inhibiting Myocardin-Related Transcription Factor Relays. Behrmann A, Zhong D, Li L, Cheng SL, Mead M, Ramachandran B, Sabaeifard P, Goodarzi M, Lemoff A, Kronenberg HM, Towler DA, Circ Res 2020 May 126 10 1363-1378 Improved effect of amikacin-loaded poly(D,L-lactide-co-glycolide) nanoparticles against planktonic and biofilm cells of Pseudomonas aeruginosa. Sabaeifard P, Abdi-Ali A, Gamazo C, Irache JM, Soudi MR, J Med Microbiol 2017 Mar 66 2 137-148 Amikacin loaded PLGA nanoparticles against Pseudomonas aeruginosa. Sabaeifard P, Abdi-Ali A, Soudi MR, Gamazo C, Irache JM, Eur J Pharm Sci 2016 Oct 93 392-8 Results 1-7 of 7 1 Books Featured Books Microbial Corrosion volume 2 (in Farsi) Kasra Kermanshahi, R., Heshmat Dehkordi, E, Bahrami Bavani, M, Alimadadi, N., Sabaeifard, P. (2024). Tehran, Iran, Iranian corrosion Association Microbial Corrosion volume 1 (in Farsi) Kasra Kermanshahi, R., Heshmat Dehkordi, E, Bahrami Bavani, M, Alimadadi, N., Sabaeifard, P. (2023). Tehran, Iran, Iranian corrosion Association Microbiology (in Farsi) Sabaeifard, P., Salehi Najafabadi, A. (2011). Tehran, Iran, Olgoo Publication Honors & Awards Radiology Research Day Best Basic Science Poster Presentation AwardUT Southwestern medical center (2018) Study Abroad ScholarshipIran Ministry of Science, Research and Technology (2014-2016) Research Fellowship AwardIran Nanotechnology Initiative Council (2011-2016) Dean's List for High Academic AchievementAlzahra University, Tehran, Iran (2003) Professional Associations/Affiliations Microbiology Society (2023) The American Society for Microbiology (2014)
