Biography

2018-Present: Assistant Professor, Department of Immunology, UT Southwestern Medical Center

2013-2018: Postdoctoral Fellow, Department of Pharmacology, University of California, San Diego

2006-2013: Ph.D Student, Department of Microbiology and Immunology, Loyola University Chicago

Research Interest

  • Cancer Immunotherapy
  • Chronic Liver Diseases
  • Hepatocellular Carcinoma
  • Innate Immunity
  • Mitochondrial Stress Reponse
  • Tumor Immunology

Publications

Featured Publications LegendFeatured Publications

Murine macrophage autophagy protects against alcohol-induced liver injury by degrading interferon regulatory factor 1 (IRF1) and removing damaged mitochondria.
Liang S, Zhong Z, Kim SY, Uchiyama R, Roh YS, Matsushita H, Gottlieb RA, Seki E, J. Biol. Chem. 2019 Jun
Choline Uptake and Metabolism Modulate Macrophage IL-1ß and IL-18 Production.
Sanchez-Lopez E, Zhong Z, Stubelius A, Sweeney SR, Booshehri LM, Antonucci L, Liu-Bryan R, Lodi A, Terkeltaub R, Lacal JC, Murphy AN, Hoffman HM, Tiziani S, Guma M, Karin M, Cell Metab. 2019 Apr
NADPH Oxidase 1 in Liver Macrophages Promotes Inflammation and Tumor Development in Mice.
Liang S, Ma HY, Zhong Z, Dhar D, Liu X, Xu J, Koyama Y, Nishio T, Karin D, Karin G, Mccubbin R, Zhang C, Hu R, Yang G, Chen L, Ganguly S, Lan T, Karin M, Kisseleva T, Brenner DA Gastroenterology 2018 Nov
Inflammation-induced IgA+ cells dismantle anti-liver cancer immunity.
Shalapour S, Lin XJ, Bastian IN, Brain J, Burt AD, Aksenov AA, Vrbanac AF, Li W, Perkins A, Matsutani T, Zhong Z, Dhar D, Navas-Molina JA, Xu J, Loomba R, Downes M, Yu RT, Evans RM, Dorrestein PC, Knight R, Benner C, Anstee QM, Karin M Nature 2017 Nov 551 7680 340-345

Honors & Awards

  • UT Southwestern Circle of Friends Award in Cancer Research
    (2019-2020)
  • Cancer Prevention Research Institute of Texas (CPRIT) Scholar Recruitment of First-Time, Tenure-Track Faculty Members
    (2018-2023)
  • University of Texas System Rising STARs Award
    (2018-2020)
  • American Association for the Study of Liver Diseases (AASLD) Pinnacle Research Award
    (2017-2020)
  • Prevent Cancer Foundation Board of Directors Award
    (2017-2019)
  • American Association of Immunologists (AAI) Trainee Achievement Award
    (2016)
  • Cancer Research Institute Irvington Postdoctoral Fellowship Award
    (2014-2017)

Professional Associations/Affiliations

  • American Association for the Study of Liver Diseases (2017)
  • American Association for Cancer Research (2012)
  • American Association of Immunologists (2010)