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Reuben Arasaratnam, M.D.

Reuben Arasaratnam, M.D.

Titles and Appointments

Distinguished Teaching Professor

Associate Professor

Schools
Medical School
Departments
Internal Medicine
  • Biography

    Reuben Arasaratnam, M.D., M.P.H., is an Associate Professor in the Department of Internal Medicine at UT Southwestern Medical Center, and a member of the Division of Infectious Diseases and Geographic Medicine

    Originally from England, Dr. Arasaratnam holds a bachelor's degree in physiology from the University of Cambridge before receiving his medical degree with honors from the University of Oxford Medical School. He completed internal medicine residency training at Oxford University Hospitals NHS Foundation Trust and the University of North Carolina at Chapel Hill, followed by fellowship training in infectious diseases at Baylor College of Medicine in Houston, where he also completed NIH T32-funded postdoctoral training in viral immunology. Additionally, he earned a master's degree in public health from the Harvard T.H. Chan School of Public Health in Boston.

    Certified by the American Board of Internal Medicine in internal medicine and infectious diseases, Dr. Arasaratnam joined the UT Southwestern faculty in 2017.

    Dr. Arasaratnam’s scholarship focuses on diagnostic excellence, health professions education and implementation science within the field of infectious diseases. His research examines strategies to expand access to penicillin allergy assessment, particularly in resource-constrained settings, with the goal of improving patient care and antimicrobial use. His other clinical and research interests include diagnostic reasoning, immunotherapeutic approaches to viral infections, and the management of pulmonary nontuberculous mycobacterial infections.

    His contributions have been recognized through institutional and national honors, including the 2021 Rising Star Award from UT Southwestern's Leaders in Clinical Excellence program, selection as a 2022 Scholar in Diagnostic Excellence by the National Academy of Medicine, recognition as a Featured Educator by the Infectious Diseases Society of America in 2023, and election to the UT Southwestern Academy of Teachers (SWAT) in 2025. 

    He is deeply committed to the education, mentorship, and professional development of learners and faculty across the continuum of medical education. His commitment to education has been recognized through multiple teaching and mentoring awards, including Division of Infectious Diseases and Geographic Medicine Teaching Award, Division of Infectious Diseases and Geographic Medicine Mentoring Award and the SWAT Outstanding Graduate Medical Education Educator Award. He has also been invited to serve as faculty member for the Harvard Macy Institute Program for Educators in Health Professions.

    Personal Note

    Outside of medicine, Dr. Arasaratnam enjoys spending time with his family, watching soccer, and serving his local church.

  • Education
    Medical School
    (2006), Medicine
    Graduate School
    Harvard University (2008), International Health
  • Research Interest
    • Infections in the Immunocompromised Host
    • Medical Education
    • Non-tuberculous Mycobacterial Infections
    • Vaccination in Immunocompromised Host
    • Viral Immunology
  • Publications

    Star Featured Publications

    American College of Rheumatology Guidance for COVID-19 Vaccination in Patients With Rheumatic and Musculoskeletal Diseases: Version 1.
    Curtis JR, Johnson SR, Anthony DD, Arasaratnam RJ, Baden LR, Bass AR, Calabrese C, Gravallese EM, Harpaz R, Sadun RE, Turner AS, Williams EA, Mikuls TR, Arthritis Rheumatol 2021 07 73 7 1093-1107
    American College of Rheumatology Guidance for the Management of Rheumatic Disease in Adult Patients During the COVID-19 Pandemic: Version 1.
    Mikuls TR, Johnson SR, Fraenkel L, Arasaratnam RJ, Baden LR, Bermas BL, Chatham W, Cohen S, Costenbader K, Gravallese EM, Kalil AC, Weinblatt ME, Winthrop K, Mudano AS, Turner A, Saag KG, Arthritis & rheumatology (Hoboken, N.J.) 2020 Apr
    Letermovir successfully used for secondary prophylaxis in a heart transplant recipient with ganciclovir-resistant cytomegalovirus syndrome (UL97 mutation).
    Chong PP, Teiber D, Prokesch BC, Arasaratnam RJ, Peltz M, Drazner MH, Garg S Transpl Infect Dis 2018 Jul e12965
    Dynamics of virus-specific T cell immunity in pediatric liver transplant recipients.
    Arasaratnam RJ, Tzannou I, Gray T, Aguayo-Hiraldo PI, Kuvalekar M, Naik S, Gaikwad A, Liu H, Miloh T, Vera JF, Himes RW, Munoz FM, Leen AM Am. J. Transplant. 2018 Jun
    Ibrutinib Use Complicated by Progressive Multifocal Leukoencephalopathy.
    Hsiehchen D, Arasaratnam R, Raj K, Froehlich T, Anderson L, Oncology 2018 95 5 319-322
    Characterizing the Cellular Immune Response to Parainfluenza Virus 3.
    Aguayo-Hiraldo PI, Arasaratnam RJ, Tzannou I, Kuvalekar M, Lulla P, Naik S, Martinez CA, Piedra PA, Vera JF, Leen AM J. Infect. Dis. 2017 Jul 216 2 153-161
    Posttransplant Lymphoproliferative Disease Presenting as an Extracranial Mass.
    Arasaratnam RJ, Restrepo A Case Rep Transplant 2017 2017 6401086
    Recent advances in the risk factors, diagnosis and management of Epstein-Barr virus post-transplant lymphoproliferative disease.
    Aguayo-Hiraldo P, Arasaratnam R, Rouce RH, Bol Med Hosp Infant Mex 2016 Jan - Feb 73 1 31-40
    Adoptive T cell therapy for the treatment of viral infections.
    Arasaratnam RJ, Leen AM Ann Transl Med 2015 Oct 3 18 278
    Quality improvement.
    Arasaratnam R, Br J Hosp Med (Lond) 2012 May 73 5 257-61
  • Books

    Featured 

  • Honors & Awards
    • Divisional Faculty Teaching Award
      UT Southwestern (2022)
    • Harvard Macy Scholar
      Harvard Macy Institute (2022)
    • Scholar in Diagnostic Excellence
      National Academy of Medicine (2022)
    • Leaders in Clinical Excellence Rising Star Award
      UT Southwestern (2021)
    • Second Place, Fellows Research
      Houston Infectious Diseases Society (2017)
    • First Place, Research Symposium
      Baylor College of Medicine (2016)
    • First Place, Research Symposium
      Baylor College of Medicine (2016)
    • Third Place, Research Symposium
      Baylor College of Medicine (2015)
    • First Place, Research Symposium
      Baylor College of Medicine (2014)
    • David Ontjes Award
      University of North Carolina (2012)
    • David Ontjes Award for Outstanding Performance During Residency
      University of North Carolina (2012)
    • Teacher of the Month
      Oxford University Medical School (2008)
    • Teacher of the Month
      Oxford University Medical School (2007)
  • Professional Associations/Affiliations
    • American Society of Transplantation
    • Infectious Disease Society of America
    • Royal College of Physicians
    • Texas Transplant Society