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Dan Nguyen, Ph.D.

Dan Nguyen, Ph.D.

Titles and Appointments

Associate Professor

School
Medical School
Department
Radiation Oncology
Graduate Programs
Biomedical Engineering
  • Biography

    Download Curriculum Vitae

    Dan Nguyen, Ph.D., is a scientist with expertise in radiation therapy treatment planning, deep learning, and optimization techniques and algorithms. He completed his Ph.D. in Biomedical Physics in 2017 at the University of California Los Angeles (UCLA), where he worked extensively on 4π Radiotherapy, Fluence Map Optimization, and Direct Aperture Optimization techniques under the guidance and mentorship of Dr. Ke Sheng.

    Dr. Nguyen was recruited to the Division of Medical Physics and Engineering, Department of Radiation Oncology at UT Southwestern in 2017 as a faculty member. He was a founding member of the multiple-investigator lab called the Medical Artificial Intelligence and Automation (MAIA) Laboratory, which was focused to innovate, develop, and apply artificial intelligence technologies to empower clinicians—especially those with less experience or limited resources—for improved patient care. He works very closely with Dr. Steve Jiang in researching and applying deep learning technologies to various facets of radiotherapy, including treatment planning, medical imaging, and outcome prediction.

  • Education
    Undergraduate
    University of Texas-Austin (2012), Physics
    Graduate School
    Uni of California (UCLA) (2015), Biomedical Physics
    Graduate School
    Uni of California (UCLA) (2017), Biomedical Physics
  • Research Interest
    • Artificial Intelligence
    • Deep Learning
    • Optimization Techniques and Algorithms
    • Radiation Therapy
  • Publications
    Contour uncertainty assessment for MD-omitted daily adaptive online head and neck radiotherapy
    Liao CY, Maniscalco AM, Zhao H, Bai T, Choi B, Moon D, Yang D, Wang J, Zhong X, Nguyen D, Godley A, Jiang SB, Sher D, Lin M Radiotherapy and Oncology 2025 Apr 205
    Deep unsupervised clustering for prostate auto-segmentation with and without hydrogel spacer
    Zhao H, Wang B, Dohopolski M, Bai T, Jiang SB, Nguyen D Machine Learning: Science and Technology 2025 Mar 6
    Deep learning dose prediction to approach Erasmus-iCycle dosimetric plan quality within seconds for instantaneous treatment planning
    van Genderingen J, Nguyen D, Knuth F, Nomer HA, Incrocci L, Sharfo AW, Zolnay A, Oelfke U, Jiang S, Rossi L, Heijmen BJ, Breedveld S Radiotherapy and Oncology 2025 Feb 203
    PULSAR Effect: Revealing potential synergies in combined radiation therapy and immunotherapy via differential equations
    Rouf S, Moore C, Saha D, Nguyen D, Bleile ML, Timmerman R, Peng H, Jiang S Journal of Theoretical Biology 2025 Jan 596
    Quality assurance for online adaptive radiotherapy: a secondary dose verification model with geometry-encoded U-Net
    Yan S, Maniscalco A, Wang B, Nguyen D, Jiang S, Shen C Machine Learning: Science and Technology 2024 Dec 5
    Deep learning prediction of scenario doses for direct plan robustness evaluations in IMPT for head-and-neck
    Nomer HA, Knuth F, van Genderingen J, Nguyen D, Sattler M, Zolnay A, Oelfke U, Jiang S, Rossi L, Heijmen BJ, Breedveld S Physics in medicine and biology 2024 Nov 69
    Can input reconstruction be used to directly estimate uncertainty of a dose prediction U-Net model?
    Huet-Dastarac M, Nguyen D, Longton E, Jiang S, Lee J, Montero AB Medical physics 2024 Oct 51 7369-7377
    Progressive auto-segmentation for cone-beam computed tomography-based online adaptive radiotherapy
    Zhao H, Liang X, Meng B, Dohopolski M, Choi B, Cai B, Lin MH, Bai T, Nguyen D, Jiang S Physics and Imaging in Radiation Oncology 2024 Jul 31
    Performance deterioration of deep learning models after clinical deployment: a case study with auto-segmentation for definitive prostate cancer radiotherapy
    Wang B, Dohopolski M, Bai T, Wu J, Hannan R, Desai N, Garant A, Yang D, Nguyen D, Lin MH, Timmerman R, Wang X, Jiang SB Machine Learning: Science and Technology 2024 Jun 5
    Multimodal radiotherapy dose prediction using a multi-task deep learning model
    Maniscalco A, Mathew E, Parsons D, Visak J, Arbab M, Alluri P, Li X, Wandrey N, Lin MH, Rahimi A, Jiang S, Nguyen D Medical physics 2024 Jun 51 3932-3949
  • Professional Associations/Affiliations
    • American Association of Physicists in Medicine (2013)