Roger Fan, M.D. Titles and Appointments Assistant Instructor School Medical School Department Internal Medicine Biography Dr. Fan is originally from North Carolina. He earned his undergraduate degree in applied and computational mathematics from the University of North Carolina. He then earned his Doctor of Medicine from Vanderbilt University School of Medicine. He completed his residency training in internal medicine and fellowship training in pulmonary and critical care medicine at UT Southwestern. He also completed a postdoctoral research fellowship in the Laboratory of Joel Elmquist where he began investigating the role of hypothalamic signaling in sepsis. His ongoing research focuses on how specific hypothalamic circuits, particularly those involving proopiomelanocortin (POMC) neurons, regulate inflammation, autonomic function, and metabolic adaptation during sepsis. Dr. Fan aims to identify neural pathways that modulate host resilience and could serve as therapeutic targets in critical illness. In parallel with his research, Dr. Fan is dedicated to excellence in clinical care. He is board certified in internal medicine, pulmonary disease, and critical care medicine. Dr. Fan practices general pulmonology and critical care medicine at UT Southwestern Medical Center and Parkland Hospital, where he cares for patients with a wide range of respiratory and critical illnesses. He is passionate about delivering thoughtful, evidence-based care in high-acuity settings, including the intensive care unit and inpatient consult services. Education Medical School Vanderbilt University School of Medicine (2017) Residency UT Southwestern Medical Center (2020), Internal Medicine Fellowship UT Southwestern Medical Center (2025), Pulmonary & Critical Care Medicine Research Interest Endocrinology Neuroscience Respiratory Infections Sepsis Publications Featured Publications Alpha-melanocyte-stimulating hormone contributes to an anti-inflammatory response to lipopolysaccharide. Reynolds RP, Fan RR, Tinajero A, Luo X, Huen SC, Fujikawa T, Lee S, Lemoff A, Mountjoy KG, Elmquist JK, Mol Metab 2024 Sep 87 101986 Nasopharyngeal Pneumococcal Density Is Associated With Viral Activity but Not With Use of Improved Stoves Among Young Andean Children. Howard LM, Fan R, Zhu Y, Griffin MR, Edwards KM, Hartinger S, Williams JV, Vidal JE, Klugman KP, Gil AI, Lanata CF, Grijalva CG, Open Forum Infect Dis 2017 4 3 ofx161 Nasopharyngeal Pneumococcal Density and Evolution of Acute Respiratory Illnesses in Young Children, Peru, 2009-2011. Fan RR, Howard LM, Griffin MR, Edwards KM, Zhu Y, Williams JV, Vidal JE, Klugman KP, Gil AI, Lanata CF, Grijalva CG, Emerging Infect. Dis. 2016 11 22 11 1996-1999 Results 1-3 of 3 1 Professional Associations/Affiliations American College of Chest Physicians (2025) American Medical Association (2017) American Thoracic Society (2019) Dallas County Medical Society (2020) Society of Critical Care Medicine (2025) Texas Medical Association (2020)