Roger Fan, M.D. Titles and Appointments Assistant Instructor School Medical School Department Internal Medicine Biography Roger Fan, M.D., is an Assistant Professor in the Department of Internal Medicine at UT Southwestern and a member of its Division of Pulmonary & Critical Care Medicine. Originally from North Carolina, Dr. Fan holds a bachelor's degree in applied and computational mathematics from the University of North Carolina at Chapel Hill. He received his medical degree from Vanderbilt University School of Medicine in Nashville, Tennessee, and then completed internal medicine residency training and a fellowship in pulmonary and critical care medicine at UT Southwestern. He also completed a postdoctoral research fellowship in the Elmquist Laboratory, where he investigated the role of hypothalamic signaling in sepsis. Board certified in internal medicine, pulmonary disease, and critical care medicine, he joined the UT Southwestern faculty in 2025. Dr. Fan's research focuses on how specific hypothalamic circuits, particularly those involving proopiomelanocortin (POMC) neurons, regulate inflammation, autonomic function, and metabolic adaptation during sepsis. He aims to identify neural pathways that modulate host resilience and could serve as therapeutic targets in critical illness. In parallel with his research, Dr. Fan provides clinical care for patients with a range of respiratory and critical illnesses in high-acuity settings, including the intensive care unit and inpatient consult services. Education Medical School Vanderbilt University School of Medicine (2017) Residency UT Southwestern Medical Center (2020), Internal Medicine Fellowship UT Southwestern Medical Center (2025), Pulmonary & Critical Care Medicine Research Interest Endocrinology Neuroscience Respiratory Infections Sepsis Publications Featured Publications Alpha-melanocyte-stimulating hormone contributes to an anti-inflammatory response to lipopolysaccharide. Reynolds RP, Fan RR, Tinajero A, Luo X, Huen SC, Fujikawa T, Lee S, Lemoff A, Mountjoy KG, Elmquist JK, Mol Metab 2024 Sep 87 101986 Nasopharyngeal Pneumococcal Density Is Associated With Viral Activity but Not With Use of Improved Stoves Among Young Andean Children. Howard LM, Fan R, Zhu Y, Griffin MR, Edwards KM, Hartinger S, Williams JV, Vidal JE, Klugman KP, Gil AI, Lanata CF, Grijalva CG, Open Forum Infect Dis 2017 4 3 ofx161 Nasopharyngeal Pneumococcal Density and Evolution of Acute Respiratory Illnesses in Young Children, Peru, 2009-2011. Fan RR, Howard LM, Griffin MR, Edwards KM, Zhu Y, Williams JV, Vidal JE, Klugman KP, Gil AI, Lanata CF, Grijalva CG, Emerging Infect. Dis. 2016 11 22 11 1996-1999 Results 1-3 of 3 1 Professional Associations/Affiliations American College of Chest Physicians American Medical Association American Thoracic Society Dallas County Medical Society Society of Critical Care Medicine Texas Medical Association