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Sachie Ogawa, Ph.D.

Sachie Ogawa, Ph.D.

Assistant Professor

School
Medical School
Department
Psychiatry
  • Biography

    Dr. Ogawa received a bachleor's degree in Biology from Kitasato University in Japan, and master degree in Biology from Kyushu University in Japan. She obtained her Ph.D. in Medical Science from Kurume University, where she studied physiological mechanisms of hippocampal neurons effected by volatile anesthetics using in vitro electrophysiological technique (Ogawa et al., Neuropharmacology, 2011).

    After an assistant professor at Kumamoto Health Science University in Japan, she conducted neural circuits connectome for neuromodulators, as a Postdoctoral Fellow at Department of Molecular and Cellular biology in Harvard University. She used modified rabies virus technique combined with transgenic mice to enable to trace cell-type specific input to two major neuromodulators, serotonin and dopamine which play important roles for flexible behaviors (Ogawa et al, Cell Reports, 2014). After that, as a Postdoctoral Associate at the Picower Institute for Learning and Memory in MIT, she studied specific neuronal circuits how memory is processed in the brain (Kitamura, Ogawa, and Roy et al., Science 2017). 

    Dr. Ogawa joined the Department of Psychiatry in 2017.

  • Research Interest
    • Circuit dissections for learning related neuronal organizations
    • Global neuronal activity for memory
    • Regulation of neurotransmitter mechanisms
  • Publications

    Star Featured Publications

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    Optogenetic activation of dopamine D1 receptors in island cells of medial entorhinal cortex inhibits temporal association learning.
    Yokose J, Yamamoto N, Ogawa SK, Kitamura T, Mol Brain 2023 Nov 16 1 78
    Systems consolidation induces multiple memory engrams for a flexible recall strategy in observational fear memory in male mice.
    Terranova JI, Yokose J, Osanai H, Ogawa SK, Kitamura T, Nat Commun 2023 Jul 14 1 3976
    Hippocampal-amygdala memory circuits govern experience-dependent observational fear.
    Terranova JI, Yokose J, Osanai H, Marks WD, Yamamoto J, Ogawa SK, Kitamura T, Neuron 2022 Feb
    Neuronal Ensembles Organize Activity to Generate Contextual Memory.
    Marks WD, Yokose J, Kitamura T, Ogawa SK, Front Behav Neurosci 2022 16 805132
  • Professional Associations/Affiliations
    • Association for Neurons and Brain Disease (2014)
    • Physiological Society of Japan (2010)
    • Society for Japanese Neuroscience (2014)
    • Society for Neuroscience (2011)