Bo-Jui Chang, Ph.D. Titles and Appointments Assistant Professor Schools Medical School | Graduate School Departments Lyda Hill Department of Bioinformatics Graduate Programs Biomedical Engineering Biography Download Curriculum Vitae Since 2022, Bo-Jui Chang has been appointed as Assistant Professor in the Lyda Hill Department of Bioinformatics. He was a senior research scientist (2019-2022) and an assistant instructor (2017-2019) in Reto Fiolka’s lab. Before moving to UTSW, Bo-Jui was a postdoctoral researcher in Dr. Bi-Chang Chen’s lab (2016 - 2017) at Academia Sinica, Taiwan, in Dr. Ernst Stelzer’s lab (2011-2016) at Goethe University Frankfurt, Germany, and in Dr. Su-Yu Chiang’s lab (2007-2011) at National Synchrotron Radiation Research Center, Taiwan. Education Graduate School National Chiao Tung University (2006), Physics Research Interest Combine super-resolution microscopy, particularly structured illumination microscopy, single molecule localization microscopy, and expansion microscopy with light-sheet microscopy. Establish imaging collaborations across campus that will lead to new biological insights. Use cutting-edge light-sheet microscopes to perform 3D live imaging of single cancer cells or in the context of small organelles and spheroids. Use zebrafish as an animal model to study cancer cell biological processes. Publications Featured Publications Resolution doubling in light-sheet microscopy via oblique plane structured illumination. Chen B, Chang BJ, Roudot P, Zhou F, Sapoznik E, Marlar-Pavey M, Hayes JB, Brown PT, Zeng CW, Lambert T, Friedman JR, Zhang CL, Burnette DT, Shepherd DP, Dean KM, Fiolka RP, Nat Methods 2022 Oct Systematic and quantitative comparison of lattice and Gaussian light-sheets. Chang BJ, Dean KM, Fiolka R, Opt Express 2020 Aug 28 18 27052-27077 Universal light-sheet generation with field synthesis. Chang BJ, Kittisopikul M, Dean KM, Roudot P, Welf ES, Fiolka R Nat. Methods 2019 Mar 16 3 235-238 csiLSFM combines light-sheet fluorescence microscopy and coherent structured illumination for a lateral resolution below 100 nm. Chang BJ, Perez Meza VD, Stelzer EHK Proc. Natl. Acad. Sci. U.S.A. 2017 May 114 19 4869-4874 Erratum to: light sheet-based fluorescence microscopy (LSFM) for the quantitative imaging of cells and tissues. Pampaloni F, Chang BJ, Stelzer EH Cell Tissue Res. 2015 Oct 362 1 265 Isotropic image in structured illumination microscopy patterned with a spatial light modulator. Chang BJ, Chou LJ, Chang YC, Chiang SY, Opt Express 2009 Aug 17 17 14710-21 Real-time multi-angle projection imaging of biological dynamics. Chang BJ, Manton JD, Sapoznik E, Pohlkamp T, Terrones TS, Welf ES, Murali VS, Roudot P, Hake K, Whitehead L, York AG, Dean KM, Fiolka R, Nat Methods 2021 Jun A versatile oblique plane microscope for large-scale and high-resolution imaging of subcellular dynamics. Sapoznik E, Chang BJ, Huh J, Ju RJ, Azarova EV, Pohlkamp T, Welf ES, Broadbent D, Carisey AF, Stehbens SJ, Lee KM, Marín A, Hanker AB, Schmidt JC, Arteaga CL, Yang B, Kobayashi Y, Tata PR, Kruithoff R, Doubrovinski K, Shepherd DP, Millett-Sikking A, York AG, Dean KM, Fiolka RP, Elife 2020 11 9 Converting lateral scanning into axial focusing to speed up three-dimensional microscopy. Chakraborty T, Chen B, Daetwyler S, Chang BJ, Vanderpoorten O, Sapoznik E, Kaminski CF, Knowles TPJ, Dean KM, Fiolka R, Light Sci Appl 2020 9 165 Light-sheet microscopy of cleared tissues with isotropic, subcellular resolution. Chakraborty T, Driscoll MK, Jeffery E, Murphy MM, Roudot P, Chang BJ, Vora S, Wong WM, Nielson CD, Zhang H, Zhemkov V, Hiremath C, De La Cruz ED, Yi Y, Bezprozvanny I, Zhao H, Tomer R, Heintzmann R, Meeks JP, Marciano DK, Morrison SJ, Danuser G, Dean KM, Fiolka R, Nat. Methods 2019 Nov 16 11 1109-1113 Results 1-10 of 18 1 2 Next Last Honors & Awards Adjunct investigator, Cluster of excellent Frankfurt Macromolecular Complexes, Germany (2013-2015) EMBO Short-term fellowship, European Molecular Biology Organization, Germany (2013-2013) Postdoctoral Research Abroad Program, National Science Council, Taiwan (2011-2012) Professional Associations/Affiliations Assistant Instructor (2017-2019) Assistant professor (2022) Senior Research Scientist (2019-2022)
