Education

Undergraduate
Saint John's University (2001), Physics
Graduate School
University of Pennsylvania (2011), Physics

Research Interest

  • Cerebral metabolism and hemodynamics
  • Diffuse correlation spectroscopy (DCS)
  • Diffuse optical spectroscopy (DOS)
  • Near-infrared spectroscopy (NIRS)
  • Non-invasive monitoring
  • Spinal cord hemodynamics

Publications

Featured Publications LegendFeatured Publications

Effects of Exercise Training on Calf Muscle Oxygen Extraction and Blood Flow in Patients with Peripheral Artery Disease.
Baker WB, Li Z, Schenkel SS, Chandra M, Busch DR, Englund EK, Schmitz KH, Yodh AG, Floyd TF, Mohler ER J. Appl. Physiol. 2017 Oct jap.00585.2017
Noninvasive optical monitoring of critical closing pressure and arteriole compliance in human subjects.
Baker WB, Parthasarathy AB, Gannon KP, Kavuri VC, Busch DR, Abramson K, He L, Mesquita RC, Mullen MT, Detre JA, Greenberg JH, Licht DJ, Balu R, Kofke WA, Yodh AG J. Cereb. Blood Flow Metab. 2017 Aug 37 8 2691-2705
Longitudinal optical monitoring of blood flow in breast tumors during neoadjuvant chemotherapy.
Cochran JM, Chung SH, Leproux A, Baker WB, Busch DR, DeMichele AM, Tchou J, Tromberg BJ, Yodh AG Phys Med Biol 2017 Jun 62 12 4637-4653
Continuous cerebral hemodynamic measurement during deep hypothermic circulatory arrest.
Busch DR, Rusin CG, Miller-Hance W, Kibler K, Baker WB, Heinle JS, Fraser CD, Yodh AG, Licht DJ, Brady KM Biomed Opt Express 2016 Sep 7 9 3461-3470
Heterodyne frequency-domain multispectral diffuse optical tomography of breast cancer in the parallel-plane transmission geometry.
Ban HY, Schweiger M, Kavuri VC, Cochran JM, Xie L, Busch DR, Katrašnik J, Pathak S, Chung SH, Lee K, Choe R, Czerniecki BJ, Arridge SR, Yodh AG Med Phys 2016 Jul 43 7 4383
Cerebral Blood Flow Response to Hypercapnia in Children with Obstructive Sleep Apnea Syndrome.
Busch DR, Lynch JM, Winters ME, McCarthy AL, Newland JJ, Ko T, Cornaglia MA, Radcliffe J, McDonough JM, Samuel J, Matthews E, Xiao R, Yodh AG, Marcus CL, Licht DJ, Tapia IE Sleep 2016 Jan 39 1 209-16
Scoring system for periventricular leukomalacia in infants with congenital heart disease.
McCarthy AL, Winters ME, Busch DR, Gonzalez-Giraldo E, Ko TS, Lynch JM, Schwab PJ, Xiao R, Buckley EM, Vossough A, Licht DJ Pediatr. Res. 2015 Sep 78 3 304-9
Pressure modulation algorithm to separate cerebral hemodynamic signals from extracerebral artifacts.
Baker WB, Parthasarathy AB, Ko TS, Busch DR, Abramson K, Tzeng SY, Mesquita RC, Durduran T, Greenberg JH, Kung DK, Yodh AG Neurophotonics 2015 Jul 2 3 035004
Macroscopic optical physiological parameters correlate with microscopic proliferation and vessel area breast cancer signatures.
Chung SH, Feldman MD, Martinez D, Kim H, Putt ME, Busch DR, Tchou J, Czerniecki BJ, Schnall MD, Rosen MA, DeMichele A, Yodh AG, Choe R Breast Cancer Res. 2015 May 17 72
Time to surgery and preoperative cerebral hemodynamics predict postoperative white matter injury in neonates with hypoplastic left heart syndrome.
Lynch JM, Buckley EM, Schwab PJ, McCarthy AL, Winters ME, Busch DR, Xiao R, Goff DA, Nicolson SC, Montenegro LM, Fuller S, Gaynor JW, Spray TL, Yodh AG, Naim MY, Licht DJ J. Thorac. Cardiovasc. Surg. 2014 Nov 148 5 2181-8

Books

Featured Books Legend Featured Books

Diffuse Optical Tomography and Spectroscopy. In Molecular Imaging: Principles and Practice

David R Busch and Britton Chance (2009). BC Decker

Honors & Awards

  • Mack Technology Fellow
    (2017-2017)
  • Fulbright Scholar
    University of Campinas (UNICAMP) Brazil (2015-2016)
  • Most Promising Pediatric Medical Device
    Philadelphia Pediatric Medical Device Consortium (2015-2015)
  • Whitaker Scholar
    ICFO- The Institute of Photonic Sciences, Barcelona Spain (2014-2015)