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David Busch, Ph.D.

David Busch, Ph.D.

Titles and Appointments

Associate Professor

Schools
Medical School | Graduate School
Departments
Anesthesiology & Pain Management | Biomedical Engineering | Neurology
Graduate Programs
Biomedical Engineering, Neuroscience
  • Biography

     

    Dr. Busch’s work focuses on developing non-invasive and minimally invasive optical tools to monitor deep tissues in health and disease, as well as throughout therapy.

    He received a Ph.D. from the University of Pennsylvania (Physics) in 2011 and completed a postdoctoral fellowship in Neurology at the Children's Hospital of Philadelphia, prior to joining the faculty at the University of Texas Southwestern Medical Center in 2018. Dr. Busch is currently an assistant professor in the Departments of Anesthesiology and Pain Management, Neurology, and Biomedical Engineering, as well as a member of the Biomedical Engineering and Neuroscience Graduate Programs. 

    Dr. Busch’s research is currently supported by NIH NINDS  and NIBIB and formerly by the Fulbright, Thrasher, and Hartwell Research Foundations.

  • Education
    Undergraduate
    Saint Johns University (2001), Physics
    Graduate School
    University of Pennsylvania (2011), Physics
  • Research Interest
    • Biomedical engineering
    • Brain and spinal cord monitoring
    • Cerebral metabolism and hemodynamics
    • Diffuse correlation spectroscopy (DCS)
    • Diffuse optical spectroscopy (DOS)
    • Intraoperative neuromonitoring
    • Medical device development
    • Near-infrared spectroscopy (NIRS)
    • Non-invasive monitoring
    • Spinal cord hemodynamics
  • Publications
    EHR Sampling Interval Bias Detection and Burden of Blood Pressure Excursions: Implications for Clinical Decision Support and Model Validity in Pediatric ECMO
    Shah N, Sanford E, Busch DR, Singh R, Mathur S, Sharma J, Reeder P, Natarajan S, Raman L Information (Switzerland) 2026 Feb 17
    Compact hybrid near-infrared and speckle contrast optical spectroscopy device
    Quiroga A, Verma M, Fornasier M, Beslija F, Frisk LK, Chetia S, Yaqub MA, Beato JM, Fernadez J, Bosch V, Menino X, Senciales D, Garcia C, Acaine O, Sifuentes JC, Dave S, Cheruku S, Choi C, Lahsaei P, Tabet M, Weldon-Carroll R, Olson D, Little W, Busch DR, Durduran T 2025 Dec
    Noninvasive evaluation of microvascular impairment in intensive care patients through near-infrared spectroscopy, the multicenter HEMOCOVID-19 trial: A spotlight on recruitment center effect on measured biomarkers
    Cortese L, Masó A, Morillas M, Busch DR, Castro P, Eiras Falcão AL, Ferrer R, Grasselli G, Karadeniz U, Marin Corral J, Mesquita RC, Pérez Pacheco A, Quiroga Soto AF, Utino Taniguchi L, Zanoletti M, Mesquida J, Romero D, Durduran T 2025 Dec
    Phantom for standardization in functional near-infrared spectroscopy, part 1: implementation and usage
    Kawaguchi H, Tanikawa Y, Yamada T, Floor-Westerdijk M, Van der Hoek M, Yang L, Von Lühmann A, Britz P, Busch DR, Torricelli A, Pifferi A, Grosenick D, Wabnitz H Neurophotonics 2025 Oct 12
    The fNIRS glossary project: a consensus-based resource for functional near-infrared spectroscopy terminology
    Stute K, Gossé LK, Montero-Hernandez S, Perkins GA, Yücel MA, Cutini S, Durduran T, Ehlis AC, Ferrari M, Gervain J, Mesquita RC, Orihuela-Espina F, Quaresima V, Scholkmann F, Tachtsidis I, Torricelli A, Wabnitz H, Yodh AG, Carp SA, Dehghani H, Fang Q, Fantini S, Hoshi Y, Niu H, Obrig H, Klein F, Artemenko C, Bajracharya A, Barth B, Bartkowski C, Borot L, Bulgarelli C, Busch DR, Chojak M, DeFreitas JM, Diprossimo L, Dresler T, Eken A, Elsherif MM, Emberson LL, Exner A, Ferdous TR, Fiske A, Forbes SH, Gemignani J, Gerloff C, Guérin SM, Guevara E, de Hamilton AF, Hosseini SM, Jain D, Kerr-German AN, Kong H, Kroczek A, Longhurst JK, Lührs M, MacLennan RJ, Mehler DM, Meidenbauer KL, Moreau D, Mutlu MC, Orti R, Paranawithana I, Pinti P, Jounghani AR, Reindl V, Ross NA, Sanchez-Alonso S, Seidel-Marzi O, Shukla M, Usama SA, Talati M, Vergotte G, Yaqub MA, Yu CC, Zainodini H Neurophotonics 2025 Apr 12 27801
    PRESSURE GRADIENT AS A PREDICTOR OF TIME NEEDED TO DRAIN CEREBROSPINAL FLUID VIA AN EXTERNAL VENTRICULAR DRAIN
    Olson DM, Nairon EB, Riskey LM, Salter A, Busch DR American Journal of Critical Care 2025 Mar 34 129-136
    Non-invasive evaluation of microvascular impairment in intensive care patients through near-infrared spectroscopy - the multicenter HEMOCOVID-19 trial: a spotlight on recruitment center effect on measured biomarkers
    Author Collaboration Hc, Cortese L, Masó A, Morillas M, Busch DR, Castro P, Eiras Falcão AL, Ferrer R, Grasselli G, Karadeniz U, Marin Corral J, Mesquita RC, Pérez Pacheco A, Quiroga Soto AF, Utino Taniguchi L, Zanoletti M, Mesquida J, Romero D, Durduran T 2025
    Compact, Hybrid Near Infrared and Speckle Contrast Optical Spectroscopy Device
    Quiroga A, Verma M, Fornasier M, Beslija F, Frisk LK, Chetia S, Atif Yaqub M, Beato JM, Fernadez J, Bosch V, Menino X, Senciales D, Garcia C, Acaine O, Sifuentes JC, Dave S, Cheruku S, Choi C, Lahsaei P, Tabet M, Weldon-Carroll RC, Olson D, Little W, Busch DR, Durduran T 2025
    Correlations between Quantitative EEG Parameters and Cortical Blood Flow in Patients Undergoing Extracorporeal Membrane Oxygenation with and Without Encephalopathy
    Khan IR, Dar IA, Johnson TW, Loose E, Xu YY, Santiago E, Donohue KL, Marinescu MA, Gosev I, Schifitto G, Maddox RK, Busch DR, Choe R, Selioutski O Journal of Clinical Neurophysiology 2024 Nov 41 597-605
    Prediction of the response to antiangiogenic sunitinib therapy by non-invasive hybrid diffuse optics in renal cell carcinoma
    Mireles M, Jiménez-Valerio G, Morales-Dalmau J, Johansson JD, Martínez-Lozano M, Vidal-Rosas EE, Navarro-Pérez V, Busch DR, Casanovas O, Durduran T, Vilches C Biomedical Optics Express 2024 Oct 15 5773-5789
  • Books

    Featured 

    Diffuse Optical Tomography and Spectroscopy. In Molecular Imaging: Principles and Practice

    David R Busch and Britton Chance (2009). BC Decker

  • Honors & Awards
    • Mack Technology Fellow
      (2017-2017)
    • Fulbright Scholar
      University of Campinas (UNICAMP) Brazil (2015-2016)
    • Whitaker Scholar
      ICFO- The Institute of Photonic Sciences, Barcelona Spain (2014-2015)
  • Professional Associations/Affiliations
    • American Society for Laser Medicine and Surgery (2017)
    • International Society of Cerebral Blood Flow and Metabolism (2016)
    • Optical Society of America (2001)
    • SPIE (2002)