Dr. Shakkottai obtained his medical degree at the Christian Medical College, Vellore, India, and his PhD at the University of California, Irvine. He received his Neurology Residency training at Washington University/Barnes-Jewish hospital, and was a fellow in Movement Disorders at the University of Michigan. He joined the full-time faculty at University of Michigan in 2010. He moved to UTSW in 2021.

The long-term goal of Dr. Shakkottai’s clinical and laboratory research is to determine whether alterations in neuronal physiology contribute to motor dysfunction and degeneration in cerebelalr ataxia. Work in Dr. Shakkottai’s laboratory has identified  dysfunction in the cerebellum common to many murine models of ataxia, with identification of ion channels regulating Purkinje neuron intrinsic excitability as key targets for a shared therapeutic strategy.

Dr. Shakkottai's Clinical Interests include: Cerebellar Ataxia, Inherited & Sporadic Disorders of Cerebellar Dysfunction, Balance Disorders and Other Movement Disorders.


Medical School
Christian Medical College, India (2000)
Graduate School
University of California, Irvine (2004), Physiology & Biophysics
Washington University St. Louis - Barnes Jewish Hospital (2005), Internal Medicine
Washington University/Barnes Jewish Hospital (2008)
University of Michigan Medical School (2010), Movement Disorders

Research Interest

  • Cerebellar Ataxia
  • Ion Channel Dysfunction
  • Ion channel pharmacology and drug discovery
  • Potassium Channels
  • Purkinje Neuron
  • SCA


Featured Publications LegendFeatured Publications

Honors & Awards

  • John W Schut Research Achievement Award
    National Ataxia Foundation (2022)
  • Young Investigator Award, National Ataxia Foundation
  • Leonard Berg Award for resident research, Washington University School of Medicine
  • Dorothy Penrose Stout Award for the best predoctoral fellowship application in the Western States affiliate of the American Heart Association
  • Dr. Miriaviakulam David Memorial Medal for the best outgoing MBBS student of the graduating year of 2000, Christian Medical College, Vellore, India

Professional Associations/Affiliations

  • American Academy of Neurology (2006)
  • American Neurological Association (2012)