Juan Manuel “Juanma” Povedano Selfa, Ph.D. Titles and Appointments Assistant Professor School Medical School Department Internal Medicine | Biochemistry Graduate Programs Biological Chemistry, Cancer Biology Biography Juan Manuel "Juanma" Povedano Selfa, Ph.D., is an Assistant Professor in the Department of Internal Medicine at UT Southwestern Medical Center and a member of its Division of Endocrinology. Originally from Spain, Dr. Povedano Selfa holds a bachelor's degree in biology from the University of Alcala, and a master's degree in molecular biomedicine from the University of Autonoma of Madrid. He completed his doctoral degree with highest honors at the University Autonoma of Madrid. Before joining the UT Southwestern faculty in 2023, Dr. Povedano Selfa worked as a postdoctoral researcher in the David McFadden Lab. Publications Featured Publications Inducible mismatch repair streamlines forward genetic approaches to target identification of cytotoxic small molecules. Nguyen TP, Fang M, Kim J, Wang B, Lin E, Khivansara V, Barrows N, Rivera-Cancel G, Goralski M, Cervantes CL, Xie S, Peterson JM, Povedano JM, Antczak MI, Posner BA, Harvey CJB, Naughton BT, McFadden DG, Ready JM, De Brabander JK, Nijhawan D, Cell Chem Biol 2023 Aug TK216 targets microtubules in Ewing sarcoma cells. Povedano JM, Li V, Lake KE, Bai X, Rallabandi R, Kim J, Xie Y, De Brabander JK, McFadden DG, Cell Chem Biol 2022 Jul A Multipronged Approach Establishes Covalent Modification of ?-Tubulin as the Mode of Action of Benzamide Anti-cancer Toxins. Povedano JM, Rallabandi R, Bai X, Ye X, Liou J, Chen H, Kim J, Xie Y, Posner B, Rice L, De Brabander JK, McFadden DG, J Med Chem 2020 Nov 63 22 14054-14066 Engineering Forward Genetics into Cultured Cancer Cells for Chemical Target Identification. Povedano JM, Liou J, Wei D, Srivatsav A, Kim J, Xie Y, Nijhawan D, McFadden DG, Cell Chem Biol 2019 Jul Therapeutic effects of telomerase in mice with pulmonary fibrosis induced by damage to the lungs and short telomeres. Povedano JM, Martinez P, Serrano R, Tejera Á, Gómez-López G, Bobadilla M, Flores JM, Bosch F, Blasco MA, Elife 2018 Jan 7 Telomerase gene therapy rescues telomere length, bone marrow aplasia, and survival in mice with aplastic anemia. Bär C, Povedano JM, Serrano R, Benitez-Buelga C, Popkes M, Formentini I, Bobadilla M, Bosch F, Blasco MA, Blood 2016 Apr 127 14 1770-9 Mice with Pulmonary Fibrosis Driven by Telomere Dysfunction. Povedano JM, Martinez P, Flores JM, Mulero F, Blasco MA, Cell Rep 2015 Jul 12 2 286-99 Results 1-7 of 7 1 Honors & Awards UTSW Distinguished Postdoctoral Service Award 2021 (1st Prize) (2021) Chilton Foundation Postdoctoral Fellow, Department of Biochemistry, UT Southwestern Medical Center (2019-2020) Molecule of the year Award 2019, Department of Biochemistry, UT Southwestern Medical Center(shared with collaborator Rameshu Rallabandi, Ph.D.) (2019) EMBO Postdoctoral Long-Term Fellowship (2016-2018) Spanish Ministry of Economy and Competitiveness Ph.D. Fellow (FPI fellowship) (2012-2016) Professional Associations/Affiliations American Association for Cancer Research European Association for Cancer Research
