Biography

Srinivas obtained his Ph.D. from The University of Texas at Austin and then joined Memorial Sloan Kettering Cancer Center as an American Cancer Society Fellow with Dr. Joan Massague.

Dr. Malladi’s lab in the Department of Pathology is focused on understanding how disseminated cancer cells survive and give rise to overt metastasis at a cellular and molecular level using a multidisciplinary and integrative approach.

Research Interest

  • Cancer Invasion and Metastasis
  • Metastatic Stem Cells
  • Tumor Biology and Microenvironment

Publications

Featured Publications LegendFeatured Publications

The Apaf-1 apoptosome induces formation of caspase-9 homo- and heterodimers with distinct activities.
Wu CC, Lee S, Malladi S, Chen MD, Mastrandrea NJ, Zhang Z, Bratton SB Nat Commun 2016 Nov 7 13565
The frequency of 1,4-benzoquinone-lysine adducts in cytochrome c correlate with defects in apoptosome activation.
Fisher AA, Labenski MT, Malladi S, Chapman JD, Bratton SB, Monks TJ, Lau SS Toxicol. Sci. 2011 Jul 122 1 64-72
Deletion mutational analysis of BMRP, a pro-apoptotic protein that binds to Bcl-2.
Malladi S, Parsa KV, Bhupathi D, Rodríguez-González MA, Conde JA, Anumula P, Romo HE, Claunch CJ, Ballestero RP, González-García M Mol. Cell. Biochem. 2011 May 351 1-2 217-32

Books

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Honors & Awards

  • Cancer Prevention Research Institute of Texas
    Scholar Award (2017-2020)
  • American Cancer Society
    Research Fellow (2012-2015)
  • University of Texas - Austin Graduate Student Fellowship
    (2010)

Professional Associations/Affiliations

  • American Association for Cancer Research (2010)