Sarah Huen, M.D., Ph.D. Assistant Professor School Medical School Department Pharmacology | Internal Medicine Graduate Programs Cell and Molecular Biology You have reached the Academic Profile. For more information on the doctor and patient care, please visit the clinical profile. Biography Sarah Huen, M.D., Ph.D., is an Assistant Professor in the Departments of Internal Medicine and Pharmacology at UT Southwestern Medical Center and a member of the Division of Nephrology. Originally from Chicago, Dr. Huen earned her bachelor's and medical degrees at Northwestern University. She completed her postdoctorate degree at Yale University in New Haven, Connecticut. She completed postdoctoral training in internal medicine at New York University, as well as nephrology and immunobiology at Yale. Certified by the American Board of Internal Medicine in nephrology, Dr. Huen joined the UT Southwestern faculty in 2017. Personal Note Outside of medicine, Dr. Huen enjoys cooking, photography and hiking. Education Medical School Northwestern University Feinberg School of Medicine (2004) Residency New York University School of Medicine (2007), Internal Medicine Fellowship Yale University School of Medicine (2012), Nephrology Other Post Graduate Training Yale University School of Medicine (2013) Graduate School Yale University School of Medicine (2013), Investigative Medicine Research Interest Acute Kidney Injury Inflammation and Sepsis Inflammatory (sepsis and cancer-related) cachexia Renal Metabolism Publications Featured Publications Fasting-induced renal HMGCS2 expression does not contribute to circulating ketones. Venable AH, Lee LE, Feola K, Santoyo J, Broomfield T, Huen SC, Am J Physiol Renal Physiol 2022 Feb Hepatic FGF21 preserves thermoregulation and cardiovascular function during bacterial inflammation. Huen SC, Wang A, Feola K, Desrouleaux R, Luan HH, Hogg R, Zhang C, Zhang QJ, Liu ZP, Medzhitov R, J Exp Med 2021 Oct 218 10 Opposing Effects of Fasting Metabolism on Tissue Tolerance in Bacterial and Viral Inflammation. Wang A, Huen SC, Luan HH, Yu S, Zhang C, Gallezot JD, Booth CJ, Medzhitov R Cell 2016 Sep 166 6 1512-1525.e12 When a calorie isn't just a calorie: a revised look at nutrition in critically ill patients with sepsis and acute kidney injury. Nadamuni M, Venable AH, Huen SC, Curr Opin Nephrol Hypertens 2022 Jul 31 4 358-366 Metabolism as Disease Tolerance: Implications for Sepsis-Associated Acute Kidney Injury. Huen SC, Nephron 2021 Jun 1-4 Survey of Current Practices of Outpatient Hemodialysis for AKI Patients. Ortiz-Soriano V, Butler CR, Levy M, Huen SC, Castaneda JL, Sakhuja A, Basu RK, Liu KD, Cerda J, Neyra JA, Kidney Int Rep 2021 Apr 6 4 1156-1160 Controversies in acute kidney injury: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Conference. Ostermann M, Bellomo R, Burdmann EA, Doi K, Endre ZH, Goldstein SL, Kane-Gill SL, Liu KD, Prowle JR, Shaw AD, Srisawat N, Cheung M, Jadoul M, Winkelmayer WC, Kellum JA, Kidney Int 2020 Aug 98 2 294-309 Renal tubular cell spliced X-box binding protein 1 (Xbp1s) has a unique role in sepsis-induced acute kidney injury and inflammation. Ferrè S, Deng Y, Huen SC, Lu CY, Scherer PE, Igarashi P, Moe OW, Kidney Int 2019 12 96 6 1359-1373 Targeting protein translation to prevent septic kidney injury. Huen SC J. Clin. Invest. 2018 Dec Glucose metabolism mediates disease tolerance in cerebral malaria. Wang A, Huen SC, Luan HH, Baker K, Rinder H, Booth CJ, Medzhitov R Proc. Natl. Acad. Sci. U.S.A. 2018 Oct 115 43 11042-11047 Results 1-10 of 21 1 2 3 Next Last Honors & Awards Disease Oriented Clinical Scholar AwardUT Southwestern (2017) Iva Dostanic Physician-Scientist Trainee AwardYale University School of Medicine (2017) Carl W. Gottschalk Research ScholarAmerican Society of Nephrology (2016) Phi Beta KappaNorthwestern University (2000) Professional Associations/Affiliations American Heart Association, Kidney Council (2012) American Society of Nephrology (2008)
