Sarah Huen, M.D., Ph.D.

Assistant Professor

Department Internal Medicine | Pharmacology

Graduate Programs Cell and Molecular Biology

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Biography

Sarah Huen, M.D., Ph.D., is an Assistant Professor in the Departments of Internal Medicine and Pharmacology at UT Southwestern Medical Center and a member of the Division of Nephrology.

Originally from Chicago, Dr. Huen earned her bachelor's and medical degrees at Northwestern University. She completed her postdoctorate degree at Yale University in New Haven, Connecticut. She completed postdoctoral training in internal medicine at New York University, as well as nephrology and immunobiology at Yale.

Certified by the American Board of Internal Medicine in nephrology, Dr. Huen joined the UT Southwestern faculty in 2017.

Personal Note

Outside of medicine, Dr. Huen enjoys cooking, photography and hiking.

Education

Medical School: Northwestern University Feinberg School of Medicine (2004)
Residency: New York University School of Medicine (2007), Internal Medicine
Fellowship: Yale University School of Medicine (2012), Nephrology
Other Post Graduate Training: Yale University School of Medicine (2013)
Graduate School: Yale University School of Medicine (2013), Investigative Medicine

Research Interest

Acute Kidney Injury
Inflammation and Sepsis
Inflammatory (sepsis and cancer-related) cachexia
Renal Metabolism

Publications

Featured Publications

Opposing Effects of Fasting Metabolism on Tissue Tolerance in Bacterial and Viral Inflammation.: Wang A, Huen SC, Luan HH, Yu S, Zhang C, Gallezot JD, Booth CJ, Medzhitov R Cell 2016 Sep 166 6 1512-1525.e12
Targeting protein translation to prevent septic kidney injury.: Huen SC J. Clin. Invest. 2018 Dec
Glucose metabolism mediates disease tolerance in cerebral malaria.: Wang A, Huen SC, Luan HH, Baker K, Rinder H, Booth CJ, Medzhitov R Proc. Natl. Acad. Sci. U.S.A. 2018 Oct 115 43 11042-11047
Acute Kidney Injury After Burn: A Cohort Study From the Parkland Burn Intensive Care Unit.: Clark AT, Li X, Kulangara R, Adams-Huet B, Huen SC, Madni TD, Imran JB, Phelan HA, Arnoldo BD, Moe OW, Wolf SE, Neyra JA J Burn Care Res 2018 Sep
Macrophages in Renal Injury and Repair.: Huen SC, Cantley LG Annu. Rev. Physiol. 2017 Feb 79 449-469
Molecular phenotyping of clinical AKI with novel urinary biomarkers.: Huen SC, Parikh CR Am. J. Physiol. Renal Physiol. 2015 Sep 309 5 F406-13
GM-CSF Promotes Macrophage Alternative Activation after Renal Ischemia/Reperfusion Injury.: Huen SC, Huynh L, Marlier A, Lee Y, Moeckel GW, Cantley LG J. Am. Soc. Nephrol. 2015 Jun 26 6 1334-45
Macrophage-mediated injury and repair after ischemic kidney injury.: Huen SC, Cantley LG Pediatr. Nephrol. 2015 Feb 30 2 199-209
Macrophage-specific deletion of transforming growth factor-?1 does not prevent renal fibrosis after severe ischemia-reperfusion or obstructive injury.: Huen SC, Moeckel GW, Cantley LG Am. J. Physiol. Renal Physiol. 2013 Aug 305 4 F477-84
Predicting acute kidney injury after cardiac surgery: a systematic review.: Huen SC, Parikh CR Ann. Thorac. Surg. 2012 Jan 93 1 337-47

Honors & Awards

Disease Oriented Clinical Scholar Award
UT Southwestern (2017)
Iva Dostanic Physician-Scientist Trainee Award
Yale University School of Medicine (2017)
Carl W. Gottschalk Research Scholar
American Society of Nephrology (2016)
Phi Beta Kappa
Northwestern University (2000)

Professional Associations/Affiliations

American Heart Association, Kidney Council (2012)
American Society of Nephrology (2008)