Dustin Hancks, Ph.D.

 Featured Publications

Norovirus MLKL-like protein initiates cell death to induce viral egress.

Wang G, Zhang D, Orchard RC, Hancks DC, Reese TA, Nature 2023 Apr 616 7955 152-158

Mitochondria and Viral Infection: Advances and Emerging Battlefronts.

Sorouri M, Chang T, Hancks DC, mBio 2022 Jan e0209621

Evolutionary profile for (host and viral) MLKL indicates its activities as a battlefront for extensive counteradaptation.

Palmer S, Chappidi S, Pinkham C, Hancks DC, Mol Biol Evol 2021 Aug

Signatures of host-pathogen evolutionary conflict reveal MISTR-A conserved MItochondrial STress Response network.

Sorouri M, Chang T, Jesudhasan P, Pinkham C, Elde NC, Hancks DC, PLoS Biol 2020 12 18 12 e3001045

FEAR antiviral response pathway is independent of interferons and countered by poxvirus proteins.

Rex EA, Seo D, Chappidi S, Pinkham C, Brito Oliveira S, Embry A, Heisler D, Liu Y, Munir M, Luger K, Alto NM, da Fonseca FG, Orchard R, Hancks DC, Gammon DB, Nat Microbiol 2024 Mar

Virologs, viral mimicry, and virocell metabolism: The expanding scale of cellular functions encoded in the complex genomes of giant viruses.

Moniruzzaman M, Erazo-Garcia PM, Farzad R, Ha AD, Jivaji A, Karki S, Sheyn U, Stanton J, Minch B, Stephens D, Hancks DC, Rodrigues RA, Abrahao JS, Vardi A, Aylward FO, FEMS Microbiol Lett 2023 Sep

Species-specific self-DNA detection mechanisms by mammalian cyclic GMP-AMP synthases.

Mosallanejad K, Kennedy SN, Bahleda KM, Slavik KM, Zhou W, Govande AA, Hancks DC, Kranzusch PJ, Kagan JC, Sci Immunol 2023 Jan 8 79 eabp9765

Overlapping Patterns of Rapid Evolution in the Nucleic Acid Sensors cGAS and OAS1 Suggest a Common Mechanism of Pathogen Antagonism and Escape.

Hancks DC, Hartley MK, Hagan C, Clark NL, Elde NC PLoS Genet. 2015 May 11 5 e1005203