Skip to Main Content
Brendan Kelley, M.D.

Brendan Kelley, M.D.

Vice Chair for Clinical Operations

Professor

School
Medical School
Department
Neurology

You have reached the Academic Profile.

For more information on the doctor and patient care, please visit the clinical profile.

  • Biography

    Joined UT Southwestern: 2017

    Clinical Interests: Brendan Kelley, M.D., is the Clinical Vice-Chair of the Department of Neurology at UT Southwestern Medical Center. He specializes in the evaluation and study of neurological causes of impairment in memory and cognition. Dr. Kelley is highly committed to the care of patients having disorders of memory and cognition. He regularly receives accolades for his outstanding patient satisfaction and collegiality.

    Trainee Education: Dr. Kelley is the Program Director of the Behavioral Neurology and Neuropsychiatry Fellowship. His enthusiasm for the field and dedication to the role of educator contribute meaningfully to the education of residents, graduate students, and fellows, ensuring the future progress of treating these challenging diseases.

    Research: Dr. Kelley’s research activity focuses on the clinical translation of novel techniques to study emerging techniques to better identify changes in the brain and spinal fluid related to Alzheimer’s disease and other dementias. He collaborates with investigators in many of the research labs at UT Southwestern that conduct basic scientific investigations aimed to better understand the biological processes that cause neurodegeneration, and to improve our ability to detect these changes before irreversible cognitive impairments have occurred. He also participates in clinical research trials conducted throughout the United States which are aimed to test new compounds as potential treatments for dementia. Dr. Kelley has authored numerous peer-reviewed scientific articles and book chapters related to Alzheimer’s disease and other dementias.

    Background: A native of Ohio, Dr. Kelley earned his medical degree at The Ohio State University and the Executive MBA Program at The Ohio State University’s Fisher College of Business. He also earned a master’s degree in Physics at Cornell University. Dr. Kelley completed a residency in neurology at the Cleveland Clinic and then received advanced fellowship training in Behavioral Neurology and Multiple Sclerosis at the Mayo Clinic.

    Dr. Kelley returned to The Ohio State University in 2014, where his clinical work and research focused on Alzheimer’s disease and Lewy body dementia. While there, he established a fellowship program in Behavioral Neurology and Neuropsychiatry. Before that, he served as the Bob and Sandy Heimann Chair for Alzheimer’s Disease Research and Education in the University of Cincinnati Department of Neurology from 2008 to 2013.

    Certified by the American Board of Psychiatry and Neurology and in Behavioral Neurology by the Unified Council of Neurological Subspecialties, Dr. Kelley proudly joined the UT Southwestern faculty in 2017.

  • Education
    Medical School
    The Ohio State University College of Medicine (2002)
    Internship
    Cleveland Clinic Foundation (2003), Internal Medicine
    Residency
    Cleveland Clinic Foundation (2006), Neurology
    Fellowship
    Mayo Clinic College of Medicine and Science (2007), Behavioral Neurology
    Fellowship
    Mayo Clinic College of Science and Medicine (2008), Multiple Sclerosis
  • Research Interest
    • Alzheimer's Disease
    • Atypical Dementias
    • Frontotemporal Dementia
    • Lewy Body Dementia
    • Mild Cognitive Impairment
    • Young-Onset Dementia
  • Publications
    Preventing cognitive decline by reducing BP target (PCOT): A randomized, pragmatic, multi-health systems clinical trial
    Giacona JM, Bates BM, Sundaram V, Brinker S, Moss E, Paspula R, Kassa S, Zhang R, Ahn C, Zhang S, Basit M, Burkhalter L, Cullum CM, Carlew A, Kelley BJ, Plassman BL, Vazquez M, Vongpatanasin W Contemporary Clinical Trials 2024 Mar 138
    Prognostic relevance of gait-related cognitive functions for dementia conversion in amnestic mild cognitive impairment
    Author Collaboration TA, Tuena C, Maestri S, Serino S, Pedroli E, Stramba-Badiale M, Riva G, Silbert LC, Lind B, Crissey R, Kaye JA, Carter R, Dolen S, Quinn J, Schneider LS, Pawluczyk S, Becerra M, Teodoro L, Dagerman K, Spann BM, Brewer J, Fleisher A, Vanderswag H, Ziolkowski J, Heidebrink JL, Zbizek-Nulph L, Lord JL, Albers CS, Petersen R, Mason SS, Knopman D, Johnson K, Villanueva-Meyer J, Pavlik V, Pacini N, Lamb A, Kass JS, Doody RS, Shibley V, Chowdhury M, Rountree S, Dang M, Stern Y, Honig LS, Kelley B, Nguyen T, Womack K, Womack KB, Quiceno M, Hajjar I, Kerwin D BMC Geriatrics 2023 Dec 23
    Circular-SWAT for deep learning based diagnostic classification of Alzheimer's disease: application to metabolome data
    Author Collaboration AD, Author Collaboration AD, Jo T, Kim J, Bice P, Huynh K, Wang T, Arnold M, Meikle PJ, Giles C, Kaddurah-Daouk R, Saykin AJ, Nho K, Kueider-Paisley A, Doraiswamy PM, Blach C, Moseley A, Thompson W, St John-Williams L, Mahmoudiandehkhordi S, Tenenbaum J, Welsh-Balmer K, Plassman B, Risacher SL, Kastenmüller G, Han X, Baillie R, Knight R, Dorrestein P, Brewer J, Mayer E, Labus J, Baldi P, Gupta A, Fiehn O, Barupal D, Meikle P, Mazmanian S, Rader D, Kling M, Shaw L, Trojanowski J, van Duijin C, Nevado-Holgado A, Bennett D, Krishnan R, Keshavarzian A, Vogt R, Kelley B, Quiceno M, Hajjar I, Kerwin D EBioMedicine 2023 Nov 97
    Regional Neuroanatomic Effects on Brain Age Inferred Using Magnetic Resonance Imaging and Ridge Regression
    Author Collaboration AD, Massett RJ, Maher AS, Imms PE, Amgalan A, Chaudhari NN, Chowdhury NF, Irimia A, Weiner MW, Aisen P, Petersen R, Jack CR, Jagust W, Trojanowki JQ, Toga AW, Beckett L, Green RC, Saykin AJ, Morris JC, Perrin RJ, Shaw LM, Khachaturian Z, Carrillo M, Potter W, Barnes L, Bernard M, González H, Ho C, Hsiao JK, Jackson J, Masliah E, Masterman D, Okonkwo O, Ryan L, Silverberg N, Fleisher A, Sacrey DT, Fockler J, Conti C, Veitch D, Neuhaus J, Jin C, Nosheny R, Ashford M, Kelley B, Nguyen T, Womack K, Womack KB, Quiceno M, Hajjar I, Kerwin D Journals of Gerontology - Series A Biological Sciences and Medical Sciences 2023 Jun 78 872-881
    A predictive model using the mesoscopic architecture of the living brain to detect Alzheimer’s disease
    Author Collaboration TA, Inglese M, Patel N, Linton-Reid K, Loreto F, Win Z, Perry RJ, Carswell C, Grech-Sollars M, Crum WR, Lu H, Malhotra PA, Silbert LC, Lind B, Crissey R, Kaye JA, Carter R, Dolen S, Quinn J, Schneider LS, Pawluczyk S, Becerra M, Teodoro L, Dagerman K, Spann BM, Brewer J, Vanderswag H, Fleisher A, Ziolkowski J, Heidebrink JL, Lord JL, Zbizek-Nulph L, Petersen R, Mason SS, Albers CS, Knopman D, Johnson K, Villanueva-Meyer J, Pavlik V, Pacini N, Lamb A, Kass JS, Doody RS, Shibley V, Chowdhury M, Nguyen T, Quiceno M, Hajjar I, Kerwin D, Kelley B Communications Medicine 2022 Dec 2
    Psychotic depression in older adults following the sudden loss of a spouse during the COVID-19 pandemic: a case series
    Eichenberger AR, Carlew AR, Kelley BJ, Camp ME Journal of Gerontology and Geriatrics 2022 Dec 70 297-299
    Using RBANS to characterize cognitive treatment response in autoimmune encephalopathy
    Kelley BJ, Bratt R, Lobue C Clinical Neurology and Neurosurgery 2022 Nov 222
    Cognitive Decline in Older People with Multiple Sclerosis—A Narrative Review of the Literature
    Chiang HS, Khera A, Stopschinski BE, Stuve O, Hart J, Kelley B, Nguyen T Geriatrics (Switzerland) 2022 Jun 7
    Linking Problems Reported by Care Partners of Individuals With Alzheimer’s Disease and Lewy Body Dementia to the International Classification of Functioning Disability and Health
    Kew CL, Juengst SB, Kelley B, Osborne CL Gerontology and Geriatric Medicine 2022 Mar 8
    Diagnostic Utility of Hippocampal Volumetric Data in a Memory Disorder Clinic Setting
    Ruchinskas R, Nguyen T, Womack K, Khera A, Yu FF, Kelley BJ Cognitive and Behavioral Neurology 2022 Mar 35 66-75
  • Books

    Featured 

  • Honors & Awards
    • UT Southwestern APP Champion of the Year
      (2020)
    • Buckeye Pride Award for Patient Satisfaction
      (2015-2017)
    • Columbus Monthly Top Doctors
      (2015-2017)
    • Cincinnati Magazine Top Doctors
      (2010-2014)
    • Bob and Sandy Heimann Chair for Alzheimer’s Disease Research and Education, University of Cincinnati Department of Neurology
      (2008-2013)
    • AAN Award for Excellence in Clinical Neurology
      (2002)
    • The Ohio State University Neurology Department Award for Outstanding Performance
      (2002)
    • Excellence in Teaching Award, The Ohio State University Department of Physics
      (1995)
    • J. D. and C. D. Smith award, The Ohio State University Department of Physics
      (1995)
    • Summa Cum Laude, The Ohio State University
      (1995)
    • Outstanding Scholar in the College of Humanities, The Ohio State University
      (1993)
    • Distinguished Scholar Award, The Ohio State University
      (1992)
    • Dobro Slovo (National Slavic Studies Honor Society)
      (1992)
    • Phi Beta Kappa, The Ohio State University
      (1992)
  • Professional Associations/Affiliations
    • Fellow - American Academy of Neurology (2000)
    • Fellow - American Neurological Association (2013)