Dr. Renie Guilliod is an anesthesiologist and a hyperbaric and diving medicine specialist, with expertise in the treatment of non-healing wounds and lymphatic disorders (lymphedema). He joined the UT Southwestern faculty in 2016, and leads the team that maintains the state-of-the-art care and academic program of the Hyperbaric Medicine Unit - Institute for Exercise and Environmental Medicine, located at Texas Health Presbyterian Hospital Dallas, which is long standing collaborative program between UT Southwestern and Texas Health Resources (see ).

He earned his medical degree and completed his residency training in anesthesiology at the Central University of Venezuela. He is one of the first physicians to be fellowship-trained in hyperbaric and diving medicine following graduation from the University of Maryland Medical Center in Baltimore. He also trained in diving and hyperbaric medicine with the United States Navy and the National Oceanic and Atmospheric Administration (NOAA). In 1994, he received recognition as a U.S. Navy Diving Medical Officer (first civilian foreigner to complete this training, graduating with honors). He is a bell/mixed-gas/saturation diver and supervisor, as well as a Diving Medical Advisory Committee and European Diving Technical Committee (DMAC/EDTC) med level IIb, certified to perform fitness to dive examinations and manage diving accidents.

Dr. Guilliod was chosen in 1999 as one of the medical directors of Divers Alert Network (DAN) and between 2006 and 2008, he served as President of the Latin-American Chapter of the Undersea and Hyperbaric Medical Society. Between 2005 and 2015, he was Assistant Professor of Anesthesiology and Internal Medicine, and Director of Research of the Division of Hyperbaric Medicine at UT Medical School, Houston. He was in charge of the academic program and led the management of hyperbaric emergencies. His expertise with the care of critically ill patients in hyperbaric chambers was vital to provide this service, which still is only available in a small number of hospital-based hyperbaric oxygen therapy centers.

During the last ten years, Dr. Guilliod’s research work has focused on the study of the lymphatic system in post-cancer treatment patients, patients born with lymphedema, and patients with non-healing wounds. He is part of the team that developed the Near-infrared Fluorescence Lymphatic Imaging System (NIRFLI) that allows the visualization of the lymphatic vasculature functioning in real time. His work has allowed the evaluation of anatomical and functional lymphatic abnormalities and their potential treatments, as well as leading to the discovery of several gene mutations and deletions responsible for triggering lymphedema. This will ultimately translate to discoveries toward treatments and better management of lymphedema and non-healing wounds.

Dr. Guilliod has also been an investigator for NASA evaluating how mild hypobaric-hypoxia affects human brain function, paralleling the type of environment the astronauts will experience in the next generation of space vehicles.


Hospital Dr. Jose Maria Vargas, Instituto Venezolano de Serguros Sociales IVSS. Venezuela (1992), Rotating
Medical School
Luis Razetti Medical School, Universidad Central de Venezuela (1992)
University of Maryland Medical Center (1994), Hyperbaric Medicine
Universidad Central de Venezuela (2004), Anesthesiology

Research Interest

  • Endothelium
  • Environmental Medicine
  • Hypoxia/Hyperoxia
  • Ischemic/Reperfusion Injury
  • Lymphatic System
  • Oxidative Stress


Featured Publications LegendFeatured Publications

Discussion: An Update on the Appropriate Role for Hyperbaric Oxygen: Indications and Evidence.
Guilliod RR, Pompeo MQ Plast. Reconstr. Surg. 2016 Sep 138 3 Suppl 117S-8S
A novel mutation in CELSR1 is associated with hereditary lymphedema.
Gonzalez-Garay ML, Aldrich MB, Rasmussen JC, Guilliod R, Lapinski PE, King PD, Sevick-Muraca EM Vascular cell 2016 8 1
Near-infrared fluorescence lymphatic imaging in a patient treated for venous occlusion.
Rasmussen JC, Aldrich MB, Guilliod R, Fife CE, O'Donnell TF, Sevick-Muraca EM J Vasc Surg Cases 2015 Sep 1 3 201-204
An abnormal lymphatic phenotype is associated with subcutaneous adipose tissue deposits in Dercum's disease.
Rasmussen JC, Herbst KL, Aldrich MB, Darne CD, Tan IC, Zhu B, Guilliod R, Fife CE, Maus EA, Sevick-Muraca EM Obesity (Silver Spring) 2014 Oct 22 10 2186-92
Investigational lymphatic imaging at the bedside in a pediatric postoperative chylothorax patient.
Tan IC, Balaguru D, Rasmussen JC, Guilliod R, Bricker JT, Douglas WI, Sevick-Muraca EM Pediatr Cardiol 2014 Oct 35 7 1295-300
Evidence for SH2 domain-containing 5'-inositol phosphatase-2 (SHIP2) contributing to a lymphatic dysfunction.
Agollah GD, Gonzalez-Garay ML, Rasmussen JC, Tan IC, Aldrich MB, Darne C, Fife CE, Guilliod R, Maus EA, King PD, Sevick-Muraca EM PLoS ONE 2014 9 11 e112548
Lymphatic abnormalities are associated with RASA1 gene mutations in mouse and man.
Burrows PE, Gonzalez-Garay ML, Rasmussen JC, Aldrich MB, Guilliod R, Maus EA, Fife CE, Kwon S, Lapinski PE, King PD, Sevick-Muraca EM Proc. Natl. Acad. Sci. U.S.A. 2013 May 110 21 8621-6
Lymphatic abnormalities in the normal contralateral arms of subjects with breast cancer-related lymphedema as assessed by near-infrared fluorescent imaging.
Aldrich MB, Guilliod R, Fife CE, Maus EA, Smith L, Rasmussen JC, Sevick-Muraca EM Biomed Opt Express 2012 Jun 3 6 1256-65
Near-infrared fluorescence imaging of lymphatics in head and neck lymphedema.
Maus EA, Tan IC, Rasmussen JC, Marshall MV, Fife CE, Smith LA, Guilliod R, Sevick-Muraca EM Head Neck 2012 Mar 34 3 448-53
Direct evidence of lymphatic function improvement after advanced pneumatic compression device treatment of lymphedema.
Adams KE, Rasmussen JC, Darne C, Tan IC, Aldrich MB, Marshall MV, Fife CE, Maus EA, Smith LA, Guilloid R, Hoy S, Sevick-Muraca EM Biomed Opt Express 2010 Jul 1 1 114-125

Professional Associations/Affiliations

  • National Lymphedema Network (2010)
  • Association for the Advancement of Wound Care (2006)
  • National Board of Diving and Hyperbaric Medical Technology (1994)
  • Undersea and Hyperbaric Medical Society (1993)