Kirill Medvedev, Ph.D.
Instructor
Department Biophysics
Research Interest
- Bioinformatics
- Computational Biology
- Computational Oncology
- Machine Learning
Publications
Featured Publications
- A Fifth of the Protein World: Rossmann-like Proteins as an Evolutionarily Successful Structural unit.
- Medvedev KE, Kinch LN, Dustin Schaeffer R, Pei J, Grishin NV, J Mol Biol 2020 Dec 433 4 166788
- Functional analysis of Rossmann-like domains reveals convergent evolution of topology and reaction pathways.
- Medvedev KE, Kinch LN, Schaeffer RD, Grishin NV, PLoS Comput Biol 2019 12 15 12 e1007569
- Completeness and Consistency in Structural Domain Classifications.
- Schaeffer RD, Kinch LN, Pei J, Medvedev KE, Grishin NV, ACS Omega 2021 Jun 6 24 15698-15707
- Recent advances suggest increased influence of selective pressure in allostery.
- Bhat AS, Dustin Schaeffer R, Kinch L, Medvedev KE, Grishin NV, Curr Opin Struct Biol 2020 06 62 183-188
- ECOD: identification of distant homology among multidomain and transmembrane domain proteins.
- Schaeffer RD, Kinch L, Medvedev KE, Pei J, Cheng H, Grishin N, BMC Mol Cell Biol 2019 06 20 1 18
- Functional and evolutionary analysis of viral proteins containing a Rossmann-like fold.
- Medvedev KE, Kinch LN, Grishin NV, Protein Sci 2018 08 27 8 1450-1463
- High temperature and pressure influence the interdomain orientation of Nip7 proteins from P. abyssi and P. furiosus: MD simulations.
- Medvedev KE, Kolchanov NA, Afonnikov DA, J Biomol Struct Dyn 2018 01 36 1 68-82
- Identification of residues of the archaeal RNA-binding Nip7 proteins specific to environmental conditions.
- Medvedev KE, Kolchanov NA, Afonnikov DA, J Bioinform Comput Biol 2017 Apr 15 2 1650036
- Molecular dynamics simulations of the Nip7 proteins from the marine deep- and shallow-water Pyrococcus species.
- Medvedev KE, Alemasov NA, Vorobjev YN, Boldyreva EV, Kolchanov NA, Afonnikov DA, BMC Struct Biol 2014 Oct 14 23
- Important role of hydrophobic interactions in high-pressure adaptation of proteins.
- Afonnikov DA, Medvedev KE, Gunbin KV, Kolchanov NA, Dokl Biochem Biophys 2011 May-Jun 438 113-6