Kirill Medvedev, Ph.D.

Instructor

School: Medical School
Department: Biophysics

Research Interest

Bioinformatics
Cancer biology
Computational Biology
Machine Learning

Publications

Featured Publications

Pan-cancer structurome reveals overrepresentation of beta sandwiches and underrepresentation of alpha helical domains.: Medvedev KE, Schaeffer RD, Chen KS, Grishin NV, Sci Rep 2023 Jul 13 1 11988
Seminoma subtypes differ in the organization and functional state of the immune microenvironment.: Savelyeva AV, Medvedev KE, 3 Biotech 2023 Mar 13 3 110
Integrated Molecular Analysis Reveals 2 Distinct Subtypes of Pure Seminoma of the Testis.: Medvedev KE, Savelyeva AV, Chen KS, Bagrodia A, Jia L, Grishin NV, Cancer Inform 2022 21 11769351221132634
A Fifth of the Protein World: Rossmann-like Proteins as an Evolutionarily Successful Structural unit.: Medvedev KE, Kinch LN, Dustin Schaeffer R, Pei J, Grishin NV, J Mol Biol 2020 Dec 433 4 166788
Functional analysis of Rossmann-like domains reveals convergent evolution of topology and reaction pathways.: Medvedev KE, Kinch LN, Schaeffer RD, Grishin NV, PLoS Comput Biol 2019 12 15 12 e1007569
Structure classification of the proteins from Salmonella enterica pangenome revealed novel potential pathogenicity islands.: Medvedev KE, Zhang J, Schaeffer RD, Kinch LN, Cong Q, Grishin NV, Sci Rep 2024 May 14 1 12260
ECOD domain classification of 48 whole proteomes from AlphaFold Structure Database using DPAM2.: Schaeffer RD, Zhang J, Medvedev KE, Kinch LN, Cong Q, Grishin NV, PLoS Comput Biol 2024 Feb 20 2 e1011586
Deep Learning for Subtypes Identification of Pure Seminoma of the Testis.: Medvedev KE, Acosta PH, Jia L, Grishin NV, Clin Pathol 2024 17 2632010X241232302
Pathogenic mutation hotspots in protein kinase domain structure.: Medvedev KE, Schaeffer RD, Pei J, Grishin NV, Protein Sci 2023 Sep 32 9 e4750
DisEnrich: Database of Enriched Regions in Human Dark Proteome.: Medvedev KE, Pei J, Grishin NV, Bioinformatics 2022 Jan