Kirill Medvedev, Ph.D.

 Featured Publications

Pan-cancer structurome reveals overrepresentation of beta sandwiches and underrepresentation of alpha helical domains.

Medvedev KE, Schaeffer RD, Chen KS, Grishin NV, Sci Rep 2023 Jul 13 1 11988

Seminoma subtypes differ in the organization and functional state of the immune microenvironment.

Savelyeva AV, Medvedev KE, 3 Biotech 2023 Mar 13 3 110

Integrated Molecular Analysis Reveals 2 Distinct Subtypes of Pure Seminoma of the Testis.

Medvedev KE, Savelyeva AV, Chen KS, Bagrodia A, Jia L, Grishin NV, Cancer Inform 2022 21 11769351221132634

A Fifth of the Protein World: Rossmann-like Proteins as an Evolutionarily Successful Structural unit.

Medvedev KE, Kinch LN, Dustin Schaeffer R, Pei J, Grishin NV, J Mol Biol 2020 Dec 433 4 166788

Functional analysis of Rossmann-like domains reveals convergent evolution of topology and reaction pathways.

Medvedev KE, Kinch LN, Schaeffer RD, Grishin NV, PLoS Comput Biol 2019 12 15 12 e1007569

Structure classification of the proteins from Salmonella enterica pangenome revealed novel potential pathogenicity islands.

Medvedev KE, Zhang J, Schaeffer RD, Kinch LN, Cong Q, Grishin NV, Sci Rep 2024 May 14 1 12260

ECOD domain classification of 48 whole proteomes from AlphaFold Structure Database using DPAM2.

Schaeffer RD, Zhang J, Medvedev KE, Kinch LN, Cong Q, Grishin NV, PLoS Comput Biol 2024 Feb 20 2 e1011586

Deep Learning for Subtypes Identification of Pure Seminoma of the Testis.

Medvedev KE, Acosta PH, Jia L, Grishin NV, Clin Pathol 2024 17 2632010X241232302

Pathogenic mutation hotspots in protein kinase domain structure.

Medvedev KE, Schaeffer RD, Pei J, Grishin NV, Protein Sci 2023 Sep 32 9 e4750

DisEnrich: Database of Enriched Regions in Human Dark Proteome.

Medvedev KE, Pei J, Grishin NV, Bioinformatics 2022 Jan