David Hsieh, M.D., is an Assistant Professor in the Department of Internal Medicine at UT Southwestern Medical Center and a member of the Division of Hematology and Oncology

Originally from Tucson, Arizona, Dr. Hsieh earned his medical degree at the University of Arizona College of Medicine. He completed internal medicine residency training at Mount Auburn Hospital in Cambridge, Massachusetts. He then completed advanced training through a fellowship in hematology and oncology at UT Southwestern Medical Center. 

A Diplomate of the American Board of Internal Medicine in medical oncology, Dr. Hsieh joined the UT Southwestern faculty in 2019.

Dr. Hsieh leads clinical trials testing new drugs for liver cancers including hepatocellular carcinoma and cholangiocarcinomas. His other research interests include translational studies to understand mechanisms behind the variable effectiveness of cancer therapies between patients and the development of treatment biomarkers. He also researches processes, policies, and biases in scientific research and medicine.

Dr. Hsieh's clinical interests include hepatocellular carcinoma and biliary tract cancers including cholangiocarcinomas and gall bladder cancers. 

Dr. Hsieh's awards and honors include an Early Career Investigator Award from the Cancer Prevention and Research Institute of Texas.

Research Interest

  • Cholangiocarcinoma
  • Hepatocellular carcinoma
  • Immunotherapy
  • Liver cancer
  • Mechanisms of drug resistance
  • Predictive biomarkers

Honors & Awards

  • CPRIT Early Clinical Investigator Award
  • ASH Research Training Award for Fellows