David Hsieh, M.D., is an Assistant Professor in the Department of Internal Medicine at UT Southwestern Medical Center and a member of its Division of Division of Hematology and Oncology. He specializes in the treatment of hepatocellular carcinoma and bile duct cancers. 

Originally from Tucson, Ariz., Dr. Hsieh earned his medical degree at the University of Arizona College of Medicine. He completed a residency in internal medicine at Mount Auburn Hospital in Cambridge, Massachusetts, and completed advanced training  through a fellowship in hematology and oncology at UT Southwestern. 

Board-certified in internal medicine and medical oncology, Dr. Hsieh joined the UT Southwestern faculty in 2019.

Dr. Hsieh’s research interests include translational studies to understand mechanisms behind the variable effectiveness of cancer therapies between patients and developing new therapies for gastrointestinal cancers through clinical trials. He also conducts research on processes, policies, and biases in scientific research and medicine.

His awards and honors include an Early Career Investigator Award from the Cancer Prevention and Research Institute of Texas.



Research Interest

  • Immunotherapy
  • Liver Cancer
  • Mechanisms of Drug Resistance
  • Predictive biomarkers


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