Mingyi Chen, M.D., Ph.D.
Associate Professor

Medical School

Peking University Health Science Center, China (1992)

Graduate School

Kyoto University, Japan (2001), Pharmacology

Postdoctoral Fellowship

UCLA/Howard Hughes Medical Institute (2005), Pathology/lab Medicine

Internship

UC San Diego Health (2006), Pathology

Residency

Loma Linda University Medical Center (2009), Pathology

Fellowship

City of Hope National Medical Center (2010), Hematopathology

• Molecular pathogenesis of lymphoma and leukemia, tumor immunology and GVHD
• Sickle cell disease, thrombosis, and vascular biology
• Viral infections and cancergenesis, and cancer stem cells

Featured Publications

Alterations in cancer stem-cell marker CD44 expression predict oncologic outcome in soft-tissue sarcomas.

Henderson T, Chen M, Darrow MA, Li CS, Chiu CL, Monjazeb AM, Murphy WJ, Canter RJ J. Surg. Res. 2018 Mar 223 207-214

The Rbm38-p63 feedback loop is critical for tumor suppression and longevity.

Jiang Y, Xu E, Zhang J, Chen M, Flores E, Chen X Oncogene 2018 Mar

PD-L1 on host cells is essential for PD-L1 blockade-mediated tumor regression.

Tang H, Liang Y, Anders RA, Taube JM, Qiu X, Mulgaonkar A, Liu X, Harrington SM, Guo J, Xin Y, Xiong Y, Nham K, Silvers W, Hao G, Sun X, Chen M, Hannan R, Qiao J, Dong H, Peng H, Fu YX J. Clin. Invest. 2018 Feb 128 2 580-588

CD3-positive plasmablastic B-cell neoplasms: a diagnostic pitfall.

Pan Z, Chen M, Zhang Q, Wang E, Yin L, Xu Y, Huang Q, Yuan Y, Zhang X, Zheng G, Yuan J Mod. Pathol. 2018 Jan

Erythrophagocytosis by T-cell lymphoma cells in a patient with hereditary spherocytosis post-splenectomy.

Frame IJ, Coberly J, Fuda FS, Chen M Br. J. Haematol. 2017 Nov

Enumeration of bone marrow plasmacytoid dendritic cells by multiparameter flow cytometry as a prognostic marker following allogeneic hematopoietic stem cell transplantation.

Su RJ, Green R, Chen M Blood Cells Mol. Dis. 2017 Oct

Ninjurin 1 has two opposing functions in tumorigenesis in a p53-dependent manner.

Yang HJ, Zhang J, Yan W, Cho SJ, Lucchesi C, Chen M, Huang EC, Scoumanne A, Zhang W, Chen X Proc. Natl. Acad. Sci. U.S.A. 2017 Oct 114 43 11500-11505

Ferredoxin reductase is critical for p53-dependent tumor suppression via iron regulatory protein 2.

Zhang Y, Qian Y, Zhang J, Yan W, Jung YS, Chen M, Huang E, Lloyd K, Duan Y, Wang J, Liu G, Chen X Genes Dev. 2017 Jul

Chronic eosinophilic leukemia, NOS with t(5;12)(q31;p13)/ETV6-ACSL6 gene fusion: a novel variant of myeloid proliferative neoplasm with eosinophilia.

Su RJ, Jonas BA, Welborn J, Gregg JP, Chen M Hum Pathol (N Y) 2016 Sep 5 6-9

Expression of Lectin-like oxidized low-density lipoprotein receptor (LOX-1) in sickle cell disease vasculopathy

Chen M, Qiu H, Lin X, Nam D, Ogbu-Nwobodo L, Archibald H, Joslin A, Wun T, Sawamura T, Green R Blood Cells, Molecules and Diseases 2016 60 September 44-8

 Featured Books

Hematological disorders following bariatric surgery.. In Pathophysiology of Bariatric Surgery: Metabolism, Nutrition, Procedures, Outcomes and Adverse Effects.

Qiu H, Green R, Chen M (2016). Victor Preedy, (ed), Academic Press.

Molecular Biology of Glycogen Storage Diseases. In Molecular Pathology of Liver Diseases

Chen M. (2010). Springer's ISBN 978-1-4419-7106-7, pp. 677-682., P.S. Monga. eds. Philip T. Cagle, editor., (ed),