Mingyi Chen, M.D., Ph.D.
Professor

Medical School

Peking University Health Science Center, China (1992)

Other Post Graduate Training

Kyoto University, Japan (2001)

Graduate School

Kyoto University, Japan (2001), Pharmacology

Postdoctoral Fellowship

UCLA/Howard Hughes Medical Institute (2005), Pathology/lab Medicine

Internship

UC San Diego Health (2006), Pathology

Residency

Loma Linda University Medical Center (2009), Pathology

Fellowship

City of Hope National Medical Center (2010), Hematopathology

• Molecular pathogenesis of lymphoma and leukemia, tumor immunology and GVHD
• Sickle cell disease, thrombosis, and vascular biology
• Viral infections and cancergenesis, and cancer stem cells

Featured Publications

A Combined Biomarker of Bright CD38 and MYC =55% Is Highly Predictive of Double-/Triple-Hit High-Grade B-Cell Lymphoma.

Alsuwaidan A, Koduru P, Fuda F, Manuel Jaso J, Chen M, Rosado F, Luu HS, Sweed N, Garcia R, Doucet M, Desai NB, Kumar KA, Awan FT, Ramakrishnan Geethakumari P, Chen W, Am J Clin Pathol 2022 May

SARS-CoV-2 Infection Associated with Aplastic Anemia and Pure Red Cell Aplasia.

Lee NC, Patel BA, Etra AM, Bat T, Ibrahim IF, Vusirikala M, Chen M, Rosado F, Jaso JM, Young NS, Chen W, Blood Adv 2022 Apr

Ferredoxin reductase and p53 are necessary for lipid homeostasis and tumor suppression through the ABCA1-SREBP pathway.

Zhang Y, Mohibi S, Vasilatis DM, Chen M, Zhang J, Chen X, Oncogene 2022 Feb

Mast cell sarcoma: clinicopathologic and molecular analysis of 10 new cases and review of literature.

Matsumoto NP, Yuan J, Wang J, Shen Q, Chen X, Kim Y, Zuppan CW, Chang CC, Cui W, Chen D, Shi M, Gisriel SD, Chen M, Xu ML, Pan Z, Mod Pathol 2022 Feb

Human herpesvirus 8-negative effusion-based large B-cell lymphoma: a distinct entity with unique clinicopathologic characteristics

Gisriel SD, Yuan J, Braunberger RC, Maracaja DLV, Chen X, Wu X, McCracken J, Chen M, Xie Y, Brown LE, Li P, Zhou Y, Sethi T, McHenry A, Hauser RG, Paulson N, Tang H, Hsi ED, Wang E, Zhang QY, Young KH, Xu ML, Pan Z. Mod Pathol 2022 . 2022 May 13. doi: 10.1038/s41379-022-01091-x

Outcome and Immune Correlates of a Phase II Trial of High-Dose Interleukin-2 and Stereotactic Ablative Radiotherapy for Metastatic Renal Cell Carcinoma.

Hannan R, Mohamad O, Diaz de Leon A, Manna S, Pop LM, Zhang Z, Mannala S, Christie A, Christley S, Monson N, Ishihara D, Hsu EJ, Ahn C, Kapur P, Chen M, Arriaga Y, Courtney K, Cantarel B, Wakeland EK, Fu YX, Pedrosa I, Cowell L, Wang T, Margulis V, Choy H, Timmerman RD, Brugarolas J, Clin Cancer Res 2021 Sep

Myeloid/lymphoid neoplasm with FGFR1 rearrangement.

Germans SK, Chen M, Blood 2021 Sep 138 10 912

Lymphadenopathy with florid lymphoid and Langerhans cell hyperplasia and hemophagocytosis mimicking lymphoma after COVID-19 mRNA vaccination.

Tintle S, Chen M, EJHaem 2021 Aug

Mice deficient in the RNA binding protein Zfp871 are prone to early death and steatohepatitis in part through the p53-Mdm2 axis.

Mohibi S, Zhang J, Chen M, Chen X, Mol Cancer Res 2021 Jul

A Machine Learning Tool Using Digital Microscopy (Morphogo) for the Identification of Abnormal Lymphocytes in the Bone Marrow.

Tang G, Fu X, Wang Z, Chen M, Acta Cytol 2021 Jul 65 4 354-357

 Featured Books

Hematological disorders following bariatric surgery.. In Pathophysiology of Bariatric Surgery: Metabolism, Nutrition, Procedures, Outcomes and Adverse Effects.

Qiu H, Green R, Chen M (2016). Victor Preedy, (ed), Academic Press.

Molecular Biology of Glycogen Storage Diseases. In Molecular Pathology of Liver Diseases

Chen M. (2010). Springer's ISBN 978-1-4419-7106-7, pp. 677-682., P.S. Monga. eds. Philip T. Cagle, editor., (ed),

Enumeration of Bone Marrow Plasmacytoid Dendritic Cells by Flow Cytometry. In Immunophenotyping: Methods and Protocols

Alsuwaidanand A, Fuda F, Chen W, and Chen M (2019). New York., Springer