Mingyi Chen, M.D., Ph.D.

Medical School

Peking University Health Science Center, China (1992)

Other Post Graduate Training

Kyoto University, Japan (2001)

Graduate School

Kyoto University, Japan (2001), Pharmacology

Postdoctoral Fellowship

UCLA/Howard Hughes Medical Institute (2005), Pathology/lab Medicine

Internship

UC San Diego Health (2006), Pathology

Residency

Loma Linda University Medical Center (2009), Pathology

Fellowship

City of Hope National Medical Center (2010), Hematopathology

• Molecular pathogenesis of lymphoma and leukemia, tumor immunology and GVHD
• Sickle cell disease, thrombosis, and vascular biology
• Viral infections and cancergenesis, and cancer stem cells

Featured Publications

Preface: Artificial intelligence (AI), machine learning ML) and digital pathology integration are the next major chapter in our diagnostic pathology and laboratory medicine arena.

Rashidi HH, Chen M, Semin Diagn Pathol 2023 Mar

Artificial intelligence in clinical multiparameter flow cytometry and mass cytometry-key tools and progress.

Fuda F, Chen M, Chen W, Cox A, Semin Diagn Pathol 2023 Mar 40 2 120-128

Structural Variation Cooperates with Permissive Chromatin to Control Enhancer Hijacking-Mediated Oncogenic Transcription.

Botten G, Zhang Y, Dudnyk K, Kim YJ, Liu X, Sanders JT, Imanci A, Droin NM, Cao H, Kaphle P, Dickerson KE, Kumar KR, Chen M, Chen W, Solary E, Ly P, Zhou J, Xu J, Blood 2023 Mar

Digital pathology and artificial intelligence as the next chapter in diagnostic hematopathology.

Lin E, Fuda F, Luu HS, Cox AM, Fang F, Feng J, Chen M, Semin Diagn Pathol 2023 Feb

TP73 Isoform-specific disruption reveals a critical role of TAp73beta in growth suppression and inflammatory response.

Zhang J, Sun W, Yan W, Kong X, Shen T, Laubach K, Chen M, Chen X, Cell Death Dis 2023 Jan 14 1 14

Metabolon formation regulates branched-chain amino acid oxidation and homeostasis.

Patrick M, Gu Z, Zhang G, Wynn RM, Kaphle P, Cao H, Vu H, Cai F, Gao X, Zhang Y, Chen M, Ni M, Chuang DT, DeBerardinis RJ, Xu J, Nat Metab 2022 Nov

Disabling Uncompetitive Inhibition of Oncogenic IDH Mutations Drives Acquired Resistance.

Lyu J, Liu Y, Gong L, Chen M, Madanat YF, Zhang Y, Cai F, Gu Z, Cao H, Kaphle P, Kim YJ, Kalkan FN, Stephens H, Dickerson KE, Ni M, Chen W, Patel P, Mims AS, Borate U, Burd A, Cai SF, Yin CC, You MJ, Chung SS, Collins RH, DeBerardinis RJ, Liu X, Xu J, Cancer Discov 2022 Oct

Poly zinc finger protein ZFP14 suppresses lymphomagenesis and abnormal inflammatory response via the HOXA gene cluster.

Mohibi S, Chen M, Chen X, Zhang J, Biochim Biophys Acta Mol Basis Dis 2022 Oct 1869 1 166587

Preface of the Special Issue "COVID-19 Infection and Hematological Malignancies".

Chen M, Anderson LD, Cancers (Basel) 2022 Sep 14 18

Epstein-Barr Virus-Positive Plasma Cell Neoplasm of Nasal Cavity in an Immunocompetent Adult.

He L, Ryan MW, Chen M, JAMA Otolaryngol Head Neck Surg 2022 Aug

 Featured Books

Hematological disorders following bariatric surgery.. In Pathophysiology of Bariatric Surgery: Metabolism, Nutrition, Procedures, Outcomes and Adverse Effects.

Qiu H, Green R, Chen M (2016). Victor Preedy, (ed), Academic Press.

Molecular Biology of Glycogen Storage Diseases. In Molecular Pathology of Liver Diseases

Chen M. (2010). Springer's ISBN 978-1-4419-7106-7, pp. 677-682., P.S. Monga. eds. Philip T. Cagle, editor., (ed),

Enumeration of Bone Marrow Plasmacytoid Dendritic Cells by Flow Cytometry. In Immunophenotyping: Methods and Protocols

Alsuwaidanand A, Fuda F, Chen W, and Chen M (2019). New York., Springer

Flow cytometry in the diagnosis of autoimmune-related lymphoproliferative disorder and lymphoma in the head and neck region. In Translational Autoimmunity

Lin (Jonathan) He, Franklin Fuda, and Mingyi Chen (2023). https://doi.org/10.1016/B978-0-323-85389-7.00002-8, Elsevier Inc

Hematolymphoid Tumors of the Sinonasal Tract.. In Atlas of Sinonasal Tract Pathology. In: Jain, D., Bishop, J.A. (eds)

Rosado, F.G., Chen, M. (2023). https://doi.org/10.1007/978-981-19-7315-4_12, Springer, Singapore.

Molecular Biology and Gene Transfer Protocols. In Vascular Disease Editor: Andrew H. Baker

Chen M. (2008). www.springer.com, Humana Press

LOX-1 in endothelial dysfunction and atherosclerosis. In Inflammatory and Infectious Basis of Atherosclerosis, Editor:Jay L. Mehta

Chen M. (2012). www.springer.com, Birkhäuser Basel