Mingyi Chen, M.D., Ph.D.
Professor

Medical School

Peking University Health Science Center, China (1992)

Other Post Graduate Training

Kyoto University, Japan (2001)

Graduate School

Kyoto University, Japan (2001), Pharmacology

Postdoctoral Fellowship

UCLA/Howard Hughes Medical Institute (2005), Pathology/lab Medicine

Internship

UC San Diego Health (2006), Pathology

Residency

Loma Linda University Medical Center (2009), Pathology

Fellowship

City of Hope National Medical Center (2010), Hematopathology

• Molecular pathogenesis of lymphoma and leukemia, tumor immunology and GVHD
• Sickle cell disease, thrombosis, and vascular biology
• Viral infections and cancergenesis, and cancer stem cells

Featured Publications

Metabolon formation regulates branched-chain amino acid oxidation and homeostasis.

Patrick M, Gu Z, Zhang G, Wynn RM, Kaphle P, Cao H, Vu H, Cai F, Gao X, Zhang Y, Chen M, Ni M, Chuang DT, DeBerardinis RJ, Xu J, Nat Metab 2022 Nov

Disabling Uncompetitive Inhibition of Oncogenic IDH Mutations Drives Acquired Resistance.

Lyu J, Liu Y, Gong L, Chen M, Madanat YF, Zhang Y, Cai F, Gu Z, Cao H, Kaphle P, Kim YJ, Kalkan FN, Stephens H, Dickerson KE, Ni M, Chen W, Patel P, Mims AS, Borate U, Burd A, Cai SF, Yin CC, You MJ, Chung SS, Collins RH, DeBerardinis RJ, Liu X, Xu J, Cancer Discov 2022 Oct

Poly zinc finger protein ZFP14 suppresses lymphomagenesis and abnormal inflammatory response via the HOXA gene cluster.

Mohibi S, Chen M, Chen X, Zhang J, Biochim Biophys Acta Mol Basis Dis 2022 Oct 1869 1 166587

Preface of the Special Issue "COVID-19 Infection and Hematological Malignancies".

Chen M, Anderson LD, Cancers (Basel) 2022 Sep 14 18

Epstein-Barr Virus-Positive Plasma Cell Neoplasm of Nasal Cavity in an Immunocompetent Adult.

He L, Ryan MW, Chen M, JAMA Otolaryngol Head Neck Surg 2022 Aug

Sprod for de-noising spatially resolved transcriptomics data based on position and image information.

Wang Y, Song B, Wang S, Chen M, Xie Y, Xiao G, Wang L, Wang T, Nat Methods 2022 Aug 19 8 950-958

Hematologic Complications in Patients Hospitalized with COVID-19 Infection.

Lin E, Araj E, Markantonis J, Luu H, Chen M, Hematol Rep 2022 Jul 14 3 228-234

p73a1, a p73 C-terminal isoform, regulates tumor suppression and the inflammatory response via Notch1.

Laubach KN, Yan W, Kong X, Sun W, Chen M, Zhang J, Chen X, Proc Natl Acad Sci U S A 2022 May 119 22 e2123202119

SARS-CoV-2 Infection Associated with Aplastic Anemia and Pure Red Cell Aplasia.

Lee NC, Patel BA, Etra AM, Bat T, Ibrahim IF, Vusirikala M, Chen M, Rosado F, Jaso JM, Young NS, Chen W, Blood Adv 2022 Apr

Ferredoxin reductase and p53 are necessary for lipid homeostasis and tumor suppression through the ABCA1-SREBP pathway.

Zhang Y, Mohibi S, Vasilatis DM, Chen M, Zhang J, Chen X, Oncogene 2022 Feb

 Featured Books

Hematological disorders following bariatric surgery.. In Pathophysiology of Bariatric Surgery: Metabolism, Nutrition, Procedures, Outcomes and Adverse Effects.

Qiu H, Green R, Chen M (2016). Victor Preedy, (ed), Academic Press.

Molecular Biology of Glycogen Storage Diseases. In Molecular Pathology of Liver Diseases

Chen M. (2010). Springer's ISBN 978-1-4419-7106-7, pp. 677-682., P.S. Monga. eds. Philip T. Cagle, editor., (ed),

Enumeration of Bone Marrow Plasmacytoid Dendritic Cells by Flow Cytometry. In Immunophenotyping: Methods and Protocols

Alsuwaidanand A, Fuda F, Chen W, and Chen M (2019). New York., Springer

Flow cytometry in the diagnosis of autoimmune-related lymphoproliferative disorder and lymphoma in the head and neck region. In Translational Autoimmunity

Lin (Jonathan) He, Franklin Fuda, and Mingyi Chen (2023). https://doi.org/10.1016/B978-0-323-85389-7.00002-8, Elsevier Inc