Dr. Wang conducted his early research in gene therapy at Fudan University in China. His Ph.D training at University of Massachusetts-Amherst led him to the direction of organelle biogenesis with focus on the molecular mechanism of chloroplast protein import in Arabidopsis thaliana. Then he adapted a powerful genetic and biochemical model system, yeast (saccharomyces cerevisiae), to dissect a post translational SRP/Sec61 independent ER membrane protein targeting pathway (GET pathway, guided-entry of tai-anchored protein insertion). He currently is working on revealing the role of Autophagy in cell development, aiming to understand the molecular mechanism. His studies will shed light directly on autophagy functions in eukaryotic gametogenesis, the production of sperm (spermatogenesis) and oocytes (oogenesis), and more broadly, on how the autophagic machinery rearranges membranes for crucial aspects of development. He is father of two kids and a Chinese poem writer.
- Cell Development and Aging
- Organelle Biogenesis
- Protein Trafficking and Targeting
- atToc159 is a selective transit peptide receptor for the import of nucleus-encoded chloroplast proteins.
- Smith MD, Rounds CM, Wang F, Chen K, Afitlhile M, Schnell DJ J. Cell Biol. 2004 May 165 3 323-34
Honors & Awards
- Sara Elizabeth O'Brien Trust (Charles A. King Trust) Postdoctoral Fellowship
The Sara Elizabeth O'Brien Trust, Bank of America, N.A. (2013-2015)