Biography

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Dr. Shaul received his B.A. from Dartmouth College and his M.D. from the University of Cincinnati. He received residency training in pediatrics at the Children's Medical Center of Cincinnati/University of Cincinnati followed by fellowship training in neonatal-perinatal medicine at Women and Infant's Hospital of Rhode Island/Brown University.

He joined the faculty of the University of Texas Southwestern Medical Center in 1986, and is the holder of the Associates First Capitol Corporation Distinguished Chair in Pediatrics at UT Southwestern. He is the Director of the Center for Pulmonary and Vascular Biology and Vice Chair for Research in the Department of Pediatrics, and a member of the Integrative Biology Graduate Program in the Division of Basic Science. Dr. Shaul was President of the Society for Pediatric Research in 2005-2006.

Education

Medical School
University of Cincinnati College of Medicine (1981)
Residency
Children's Hospital Medical Center -Cincinnati (1984), Pediatrics
Fellowship
Brown University Medical School (1986), Neonatal-perinatal Medicine

Research Interest

  • apolipoprotein E receptor 2 (LRP8)
  • Caveolae, lipid rafts
  • Fc receptors and cardiometabolic disorders
  • Membrane-associated estrogen receptors
  • Nitric oxide synthase
  • Scavenger receptor class B, type I (HDL receptor)
  • Vascular basis of type 2 diabetes

Publications

Featured Publications LegendFeatured Publications

Selective Non-nuclear Estrogen Receptor Activation Decreases Stroke Severity and Promotes Functional Recovery in Female Mice.
Selvaraj UM, Zuurbier K, Whoolery C, Plautz EJ, Chambliss KL, Kong X, Zhang S, Kim SH, Katzenellenbogen BS, Katzenellenbogen JA, Mineo C, Shaul PW, Stowe AM Endocrinology 2018 Sep
Enhanced Liver Regeneration After Partial Hepatectomy in Sterol Regulatory Element-Binding Protein (SREBP)-1c-Null Mice is Associated with Increased Hepatocellular Cholesterol Availability.
Peng J, Yu J, Xu H, Kang C, Shaul PW, Guan Y, Zhang X, Su W Cell. Physiol. Biochem. 2018 May 47 2 784-799
Antiphospholipid antibodies induce thrombosis by PP2A activation via apoER2-Dab2-SHC1 complex formation in endothelium.
Sacharidou A, Chambliss KL, Ulrich V, Salmon JE, Shen YM, Herz J, Hui DY, Terada LS, Shaul PW, Mineo C Blood 2018 Mar
Cholesterol trafficking and raft-like membrane domain composition mediate scavenger receptor class B type 1-dependent lipid sensing in intestinal epithelial cells.
Morel E, Ghezzal S, Lucchi G, Truntzer C, Pais de Barros JP, Simon-Plas F, Demignot S, Mineo C, Shaul PW, Leturque A, Rousset M, Carrière V Biochim. Biophys. Acta 2018 Feb 1863 2 199-211

Books

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Honors & Awards

  • Association of American Physicians
    (2013)
  • Associates First Capitol Corporation Distinguished Chair in Pediatrics
    (2011)
  • Hall of Honor, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine
    (2010)
  • President, Society for Pediatric Research
    (2005-2006)
  • Codirector, Crystal Charity Ball Center for Research in Pediatric Critical Care
    (1997)
  • Lowe Foundation Professorship in Pediatric Critical Care Research
    (1997-2011)
  • Established Investigator Award, AHA
    (1993)

Professional Associations/Affiliations

  • Association of American Physicians (2013)
  • American Pediatric Society (2003)
  • American Society for Clinical Investigation (1999)
  • The American Physiological Society (1999)
  • Perinatal Research Society (1992-2013)
  • Society for Pediatric Research (1990)
  • American Academy of Pediatrics, Fellow (1987)
  • Dallas County Medical Society (1987)