Biography

Dr. Park received both his undergraduate and graduate degrees in Electrical Engineering. His doctoral work at Stanford University was focused on technical developments of magnetic resonance imaging (MRI) and spectroscopic imaging (MRSI) with application to preclinical glioma brain tumor metabolism. Following completion of his Ph.D. in 2012, he broadened his research into advanced biomedical imaging as a postdoctoral research fellow and a research associate in the Department of Radiology at Stanford School of Medicine. 

His research interests have built around 1) the development of novel noninvasive molecular imaging tools to elucidate in vivo metabolism and function of normal and pathological states, 2) the identification of characteristics in metabolic diseases, and 3) the application to translational and clinical investigation.

Education

Graduate School
Stanford University (2009), Electrical Engineering
Graduate School
Stanford University (2012), Electrical Engineering

Research Interest

  • Cancer metabolism
  • Development of hyperpolarized MR spectroscopic imaging methods
  • Metabolic imaging agents
  • Molecular imaging of metabolic diseases
  • Noninvasive assessment of cellular metabolism and tissue characteristics
  • Quantitative neuroimaging techniques

Publications

Featured Publications LegendFeatured Publications

Profiling carbohydrate metabolism in liver and hepatocellular carcinoma with 13C-glycerate probes.
Chen J, LaGue E, Li J, Yang C, Hackett EP, Mendoza M, Alger JR, DeBerardinis RJ, Corbin IR, Billingsley KL, Park JM, Analysis & Sensing 2021 Sep In Press
Dual-phase imaging of cardiac metabolism using hyperpolarized pyruvate
Ma J, Malloy CR, Pena S, Harrison CE, Ratnakar J, Zaha VG, Park JM, Magn Reson Med 2021 Sep In Press
Hyperpolarized NMR study of the impact of pyruvate dehydrogenase kinase inhibition on the pyruvate dehydrogenase and TCA flux in type 2 diabetic rat muscle.
Park JM, Josan S, Hurd RE, Graham J, Havel P, Bendahan D, Mayer D, Chung Y, Spielman DM, Jue T, Pflügers Archiv: European Journal of Physiology 2021 Aug In Press
13C-labeled diethyl ketoglutarate derivatives as hyperpolarized probes of 2-ketoglutarate dehydrogenase activity.
Singh J, Suh EH, Sharma G, Chen J, Hackett EP, Wen X, Sherry AD, Khemtong C, Malloy CR, Park JM, Kovács Z, Analysis & Sensing 2021 Aug In Press
Probing Cerebral Metabolism with Hyperpolarized 13C Imaging after Opening the Blood-Brain Barrier with Focused Ultrasound.
Hackett EP, Shah BR, Cheng B, LaGue E, Vemireddy V, Mendoza M, Bing C, Bachoo RM, Billingsley KL, Chopra R, Park JM, ACS Chem Neurosci 2021 Jul
Hyperpolarized 13C MR Spectroscopy Depicts in Vivo Effect of Exercise on Pyruvate Metabolism in Human Skeletal Muscle.
Park JM, Harrison CE, Ma J, Chen J, Ratnakar J, Zun Z, Liticker J, Reed GD, Chhabra A, Haller RG, Jue T, Malloy CR, Radiology 2021 Jun 204500
Cardiac T 2 * measurement of hyperpolarized 13 C metabolites using metabolite-selective multi-echo spiral imaging.
Ma J, Chen J, Reed GD, Hackett EP, Harrison CE, Ratnakar J, Schulte RF, Zaha VG, Malloy CR, Park JM, Magn Reson Med 2021 Apr
Characterization and compensation of f 0 inhomogeneity artifact in spiral hyperpolarized 13 C imaging of the human heart.
Reed GD, Ma J, Park JM, Schulte RF, Harrison CE, Chen AP, Pena S, Baxter J, Derner K, Tai M, Raza J, Liticker J, Hall RG, Dean Sherry A, Zaha VG, Malloy CR, Magn Reson Med 2021 Feb
Preoperative imaging of glioblastoma patients using hyperpolarized 13C pyruvate: Potential role in clinical decision making.
Chen J, Patel TR, Pinho MC, Choi C, Harrison CE, Baxter JD, Derner K, Pena S, Liticker J, Raza J, Hall RG, Reed GD, Cai C, Hatanpaa KJ, Bankson JA, Bachoo RM, Malloy CR, Mickey BE, Park JM, Neurooncol Adv 2021 Jan-Dec 3 1 vdab092
Super-Resolution Hyperpolarized 13C Imaging of Human Brain Using Patch-Based Algorithm.
Ma J, Park JM, Tomography 2020 Dec 6 4 343-355

Books

Featured Books Legend Featured Books

Insights on lactate metabolism in skeletal muscle based on 13C dynamic nuclear polarization studies. In Dynamic Hyperpolarized Nuclear Magnetic Resonance. Handbook of Modern Biophysics

Park JM, Jue T (2021). Springer, Cham

Kinetic modeling of enzymatic reactions in analyzing hyperpolarized NMR data. In Dynamic Hyperpolarized Nuclear Magnetic Resonance. Handbook of Modern Biophysics

Spielman DM, Park JM (2021). Springer, Cham

Honors & Awards

  • Magna Cum Laude Award
    International Society of Magnetic Resonance in Medicine (2021-2021)
  • Summa Cum Laude Award
    International Society of Magnetic Resonance in Medicine (2021-2021)
  • Grant Award - "Pyruvate and acetate metabolism after TBI: implications for cerebral energy metabolism"
    National Institute of Neurological Disorders and Stroke (R01) (2020-2025)
  • Magna Cum Laude Award
    International Society of Magnetic Resonance in Medicine (2020-2020)
  • Distinguished Reviewer
    Magnetic Resonance in Medicine (2019-2019)
  • Grant Award - "Development of hyperpolarized probes for imaging neurotransmitter synthesis"
    The Welch Foundation (2019-2022)
  • Grant Award - "Non-invasive in vivo imaging of extracellular biological milieu of cancer using hyperpolarized 89Y MRI"
    Collaborative Biomedical Research Award (2019-2021)
  • Magna Cum Laude Award
    International Society of Magnetic Resonance in Medicine (2019-2019)
  • Clinical Research Grant Award - "In Vivo Imaging of Traumatic Brain Injury Metabolism"
    The Texas Institute of Brain Injury and Repair (2017-2018)
  • Grant Award - "Imaging Mitochondrial Function in Brain of Patients with Mobility Disorders"
    The Mobility Foundation (2017-2018)
  • Magna Cum Laude Award
    International Society of Magnetic Resonance in Medicine (2016-2016)
  • Gambhir-RSL Grant
    Stanford University (2015-2016)
  • Junior Fellow
    International Society of Magnetic Resonance in Medicine (2014-2014)
  • Summa Cum Laude Award
    International Society of Magnetic Resonance in Medicine (2014-2014)
  • Magna Cum Laude Award
    International Society of Magnetic Resonance in Medicine (2013-2013)
  • Radiology Department Research Funding Award
    Stanford University (2013-2014)
  • Cambridge Foundation Fellowship
    Graduate Scholarship (2007-2009)

Professional Associations/Affiliations

  • International Society of Magnetic Resonance in Medicine (2009)