Biography

Dr. Park received both his undergraduate and graduate degrees in Electrical Engineering. His doctoral work at Stanford University was focused on technical developments of magnetic resonance imaging (MRI) and spectroscopic imaging (MRSI) with application to preclinical glioma brain tumor metabolism. Following completion of his Ph.D. in 2012, he broadened his research into advanced biomedical imaging as a postdoctoral research fellow and a research associate in the Department of Radiology at Stanford School of Medicine. 

His research interests have built around 1) the development of novel noninvasive molecular imaging tools to elucidate in vivo metabolism and function of normal and pathological states, 2) the identification of characteristics in metabolic diseases, and 3) the application to translational and clinical investigation.

Education

Graduate School
Stanford University (2009), Electrical Engineering
Graduate School
Stanford University (2012), Electrical Engineering

Research Interest

  • Cancer metabolism
  • Development of hyperpolarized MR spectroscopic imaging methods
  • Metabolic imaging agents
  • Molecular imaging of metabolic diseases
  • Noninvasive assessment of cellular metabolism and tissue characteristics
  • Quantitative neuroimaging techniques

Publications

Featured Publications LegendFeatured Publications

Hyperpolarized 15N-labeled, deuterated tris(2-pyridylmethyl)amine as an MRI sensor of freely available Zn2+ in tissues
Suh EH, Park JM, Lumata L, Sherry AD, Kovacs Z Comm Chem 2020 Nov In Press
Super-resolution hyperpolarized 13C imaging of human brain using patch-based algorithm.
Ma J, Park JM Tomography 2020 Oct In Press
Effect of Doxorubicin on Myocardial Bicarbonate Production from Pyruvate Dehydrogenase in Women with Breast Cancer.
Park JM, Reed GD, Liticker J, Putnam WC, Chandra A, Yaros K, Afzal A, MacNamara JP, Raza J, Hall RG, Baxter J, Derner K, Pena S, Kallem RR, Subramanyan I, Edpuganti V, Harrison C, Muthukumar A, Lewis C, Reddy S, Unni N, Klemow D, Syed S, Li HC, Cole SM, Froehlich T, Ayers CR, de Lemos JA, Malloy CR, Haley B, Zaha VG, Circ Res 2020 Oct
Simultaneous Assessment of Intracellular and Extracellular pH Using Hyperpolarized [1- 13C]Alanine Ethyl Ester.
Chen J, Hackett EP, Singh J, Kovács Z, Park JM, Anal. Chem. 2020 Sep 92 17 11681-11686
Assessment of hepatic pyruvate carboxylase activity using hyperpolarized [1-13 C]-l-lactate.
Chen J, Hackett EP, Kovacs Z, Malloy CR, Park JM, Magn Reson Med 2020 Sep
Assessment of Rapid Hepatic Glycogen Synthesis in Humans Using Dynamic 13C Magnetic Resonance Spectroscopy.
Stender S, Zaha VG, Malloy CR, Sudderth J, DeBerardinis RJ, Park JM, Hepatol Commun 2020 Mar 4 3 425-433
Multimodality Hyperpolarized C-13 MRS/PET/Multiparametric MR Imaging for Detection and Image-Guided Biopsy of Prostate Cancer: First Experience in a Canine Prostate Cancer Model.
Bachawal SV, Park JM, Valluru KS, Loft MD, Felt SA, Vilches-Moure JG, Saenz YF, Daniel B, Iagaru A, Sonn G, Cheng Z, Spielman DM, Willmann JK Mol Imaging Biol 2019 Feb
In vivo assessment of increased oxidation of branched-chain amino acids in glioblastoma.
Suh EH, Hackett EP, Wynn RM, Chuang DT, Zhang B, Luo W, Sherry AD, Park JM Sci Rep 2019 Jan 9 1 340
PKM2 activation sensitizes cancer cells to growth inhibition by 2-deoxy-D-glucose.
Tee SS, Park JM, Hurd RE, Brimacombe KR, Boxer MB, Massoud TF, Rutt BK, Spielman DM Oncotarget 2017 Oct 8 53 90959-90968
Hyperpolarized Sodium [1-(13)C]-Glycerate as a Probe for Assessing Glycolysis in Vivo.
Park JM, Wu M, Datta K, Liu SC, Castillo A, Lough H, Spielman DM, Billingsley KL J. Am. Chem. Soc. 2017 May

Honors & Awards

  • Grant Award - "Pyruvate and acetate metabolism after TBI: implications for cerebral energy metabolism"
    National Institute of Neurological Disorders and Stroke (R01) (2020-2025)
  • Magna Cum Laude Award
    International Society of Magnetic Resonance in Medicine (2020-2020)
  • Distinguished Reviewer
    Magnetic Resonance in Medicine (2019-2019)
  • Grant Award - "Development of hyperpolarized probes for imaging neurotransmitter synthesis"
    The Welch Foundation (2019-2022)
  • Grant Award - "Non-invasive in vivo imaging of extracellular biological milieu of cancer using hyperpolarized 89Y MRI"
    Collaborative Biomedical Research Award (2019-2021)
  • Magna Cum Laude Award
    International Society of Magnetic Resonance in Medicine (2019-2019)
  • Clinical Research Grant Award - "In Vivo Imaging of Traumatic Brain Injury Metabolism"
    The Texas Institute of Brain Injury and Repair (2017-2018)
  • Grant Award - "Imaging Mitochondrial Function in Brain of Patients with Mobility Disorders"
    The Mobility Foundation (2017-2018)
  • Magna Cum Laude Award
    International Society of Magnetic Resonance in Medicine (2016-2016)
  • Gambhir-RSL Grant
    Stanford University (2015-2016)
  • Junior Fellow
    International Society of Magnetic Resonance in Medicine (2014-2014)
  • Summa Cum Laude Award
    International Society of Magnetic Resonance in Medicine (2014-2014)
  • Magna Cum Laude Award
    International Society of Magnetic Resonance in Medicine (2013-2013)
  • Radiology Department Research Funding Award
    Stanford University (2013-2014)
  • Cambridge Foundation Fellowship
    Graduate Scholarship (2007-2009)

Professional Associations/Affiliations

  • International Society of Magnetic Resonance in Medicine (2009)