Maria Florian-Rodriguez, M.D. Titles and Appointments Associate Professor Endowed Title Dedman Family Scholar in Clinical Care Schools Medical School | Graduate School Departments Obstetrics and Gynecology | Cecil H. and Ida Green Center for Reproductive Biology Sciences Graduate Programs Biomedical Engineering You have reached the Academic Profile. For more information on the doctor and patient care, please visit the clinical profile. Education Medical School University of Puerto Rico School of Medicine (2011) Residency Temple University Hospital (2015), Obstetrics & Gynecology Fellowship UT Southwestern Medical Center (2018), Urogynecology Research Interest Cellular Senescence Pelvic floor disorders Vaginal extracellular matrix remodeling Publications Featured Publications Association of COMT genetic polymorphism with neuromodulation treatment response in women with fecal or urinary incontinence. Florian-Rodriguez M, Richter H, Carnes M, Zyczynski H, Lukacz E, Visco A, Arya L, Sung V, Mazloomdoost D, Gantz M, Am J Obstet Gynecol 2025 Mar Use of the senolytics dasatinib and quercetin for prevention of pelvic organ prolapse in a mouse animal model. Tappy E, Shi H, Pruszynski J, Florian-Rodriguez M, Aging (Albany NY) 2024 Sep 16 Quantification of senescence-associated secretory phenotype proteins in the vaginal secretions of pre- and postmenopausal women with and without prolapse. Sawyer P, Shi H, Keller P, Brown S, Florian-Rodriguez M, Aging Med (Milton) 2023 Jun 6 2 124-131 Induction of Cellular Senescence in Rat Vaginal Fibroblasts and Treatment With Senolytics: An in Vitro Model for the Study of Pelvic Organ Prolapse. Florian-Rodriguez ME, Hare AM, Gaddam NG, Shi H, Keller P, Word RA, Female Pelvic Med Reconstr Surg 2022 Jan Impact of vaginal distention on cell senescence in an animal model of pelvic organ prolapse. Hare AM, Gaddam NG, Shi H, Acevedo JF, Word RA, Florian-Rodriguez ME, Tissue Cell 2021 Sep 73 101652 Midgestation metabolic constraint in purine metabolism drives distinct strategies for placenta and fetal growth. Xu W, De La Cruz N, Woods A, Lokshtanov D, Gao S, Khan N, Wright S, Florian-Rodriguez ME, McIntire DD, Duryea EL, Nelson DB, Spong CY, Herrera CL, Hanna JH, Srivatsan S, Aguilera-Castrejon A, Solmonson A, bioRxiv 2026 Mar Vaginal biomechanical function in premenopausal and postmenopausal women with and without pelvic organ prolapse. Zhou Q, Li G, Kiley JX, Ogola B, Danso EK, Baiamonte LB, Desrosiers L, Knoepp LR, Lindsey SH, Florian-Rodriguez ME, Brown JQ, Miller KS, Sci Rep 2025 Jul 15 1 27039 Remodeling of Murine Vaginal Smooth Muscle Function with Reproductive Age and Elastic Fiber Disruption. White SE, Karbasion N, Snider JC, Florian-Rodriguez M, Bersi MR, Miller KS, Acta Biomater 2023 Dec Smooth muscle contribution to vaginal viscoelastic response. Clark-Patterson GL, Buchanan LM, Ogola BO, Florian-Rodriguez M, Lindsey SH, De Vita R, Miller KS, J Mech Behav Biomed Mater 2023 Apr 140 105702 Advances in vaginal bioengineering: Applications, techniques, and needs. Buchanan LM, Domingo MJE, White SE, Vanoven TN, Karbasion N, Bersi MR, Pence IJ, Florian-Rodriguez M, Miller KS, Curr Res Physiol 2023 6 100111 Results 1-10 of 22 1 2 3 Next Last