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Dr. Cai is a practicing neuropathologist and assistant professor in the Pathology Department at UT Southwestern Medical Center, Dallas, TX. He received his medical degree from Peking University Health Science Center, Beijing, China, PhD degree from Wesleyan University, Middletown, CT, and pathology residency and fellowship training at Washington University School of Medicine, St Louis, MO.

UTSW Medical Center is the largest referring center for muscle and nerve biopsies in Texas and receives biopsies specimens from over 100 institutions over a 6-state area. Dr. Cai's main clinical and research interests focus on the diagnosis of peripheral muscle and nerve diseases. We are the first and only clinical laboratory in the United States that has validated Morin stain for the diagnosis of macrophagic myofasciitis, a treatable, vaccine related inflammatory condition. Dr. Cai also published multiple articles on the diagnosis of diabetic neuropathy, inflammatory myopathies, congenital myopathy, and muscular dystrophies.



Medical School
Beijing Medical University, China (2001)
Other Post Graduate Training
Wesleyan University (2008)
Graduate School
Wesleyan University (2008), Biology
Postdoctoral Fellowship
University of Connecticut Health Center (2010), Neuroscience
Washington University in St. Louis School of Medicine (2014), Anatomic/neuropathology
Washington University in St. Louis School of Medicine (2015), Surgical Pathology

Research Interest

  • Meningioma
  • Neuromuscular diseases
  • Tumor ischemia and radio-resistance


Featured Publications LegendFeatured Publications

The efficacy of immunohistochemistry in the diagnosis of molecular genetic alterations in central nervous system gliomas: Next-generation sequencing of 212 mutations in 112 patients.
Daoud EV, Chkheidze R, Yell PC, Hatanpaa KJ, Raisanen JM, Cai C, Clin Neuropathol 2021 Oct
Preoperative imaging of glioblastoma patients using hyperpolarized 13C pyruvate: Potential role in clinical decision making.
Chen J, Patel TR, Pinho MC, Choi C, Harrison CE, Baxter JD, Derner K, Pena S, Liticker J, Raza J, Hall RG, Reed GD, Cai C, Hatanpaa KJ, Bankson JA, Bachoo RM, Malloy CR, Mickey BE, Park JM, Neurooncol Adv 2021 Jan-Dec 3 1 vdab092
The nuclear envelope protein Net39 is essential for muscle nuclear integrity and chromatin organization.
Ramirez-Martinez A, Zhang Y, Chen K, Kim J, Cenik BK, McAnally JR, Cai C, Shelton JM, Huang J, Brennan A, Evers BM, Mammen PPA, Xu L, Bassel-Duby R, Liu N, Olson EN, Nat Commun 2021 01 12 1 690
Biallelic loss of function variants in SYT2 cause a treatable congenital onset presynaptic myasthenic syndrome.
Donkervoort S, Mohassel P, Laugwitz L, Zaki MS, Kamsteeg EJ, Maroofian R, Chao KR, Verschuuren-Bemelmans CC, Horber V, Fock AJM, McCarty RM, Jain MS, Biancavilla V, McMacken G, Nalls M, Voermans NC, Elbendary HM, Snyder M, Cai C, Lehky TJ, Stanley V, Iannaccone ST, Foley AR, Lochmüller H, Gleeson J, Houlden H, Haack TB, Horvath R, Bönnemann CG, Am. J. Med. Genet. A 2020 Aug
Multi-Site Optical Monitoring of Spinal Cord Ischemia During Spine Distraction.
Busch D, Lin W, Cai C, Cutrone AM, Tatka J, Kovarovic BJ, Yodh AG, Floyd TF, Barsi J, J. Neurotrauma 2020 May


Featured Books Legend Featured Books

Honors & Awards

  • Keifer Graduate Research Award, Wesleyan University
  • Leadership Emerging in Academic Department (LEAD)
    Junior Faculty LEAD Program for Physician &Scientists
  • Outstanding Student Award, Beijing Medical University

Professional Associations/Affiliations

  • Pathologyoutlines (2020)
  • Chinese American Pathologists Association (CAPA) (2018)
  • Journal of Neuropathology and Experimental Neurology (JNEN) (2018)
  • Texas Medical Association (2017)
  • College of American Pathologists (CAP) (2015)
  • American Association of Neuropathologists (AANP) (2014)
  • American Board of Pathology (ABP) (2014)
  • United States and Canadian Academy of Pathology (USCAP) (2014)