Berge A. Minassian, M.D., is a Professor in the Departments of Pediatrics, Neurology and Neurotherapeutics, and Neuroscience at UT Southwestern. He is the Division Chief of Child Neurology and serves on the faculty of the Children's Medical Center Research Institute at UT Southwestern.

Dr. Minassian is a pediatric neurologist whose clinical specialties are epilepsy, neurodegenerative diseases, and neurogenetic conditions. Two of his primary interests have been Lafora disease, for which his lab discovered the genes, and Gene Therapy for neurological diseases of children.

He has published more than 120 scholarly articles and authored or contributed to 10 books, and his many professional honors include the Jacob's Ladder 2014 Norman Saunders International Research Prize for Outstanding Scientist, the American Academy of Neurology 2007 Dreifuss-Penry Epilepsy Award, the Canadian Paediatric Society 2008 Sanofi Pasteur Research Award, and the American Epilepsy Society 1996 Young Investigator Award. Dr. Minassian is a Fellow (Neurology) of the Royal College of Physicians and Surgeons of Canada.


Medical School
McGill University Faculty of Medicine (1992)
University of Toronto Hospitals, Canada (1993), Internal Medicine
West Los Angeles VA Medical Center (1996), Neurology
University of Toronto, the Hospital for Sick Children (1997), Pediatric Neurology
University of Toronto, the Hospital for Sick Children (1998), Neurogenetics

Research Interest

  • Gene therapy for childhood neurological diseases
  • Lafora Disease


Featured Publications LegendFeatured Publications

EEG of asymptomatic first-degree relatives of patients with juvenile myoclonic, childhood absence and rolandic epilepsy: a systematic review and meta-analysis.
Tashkandi M, Baarma D, Tricco AC, Boelman C, Alkhater R, Minassian BA Epileptic Disord 2019 Feb 21 1 30-41
MYORG is associated with recessive primary familial brain calcification.
Arkadir D, Lossos A, Rahat D, Abu Snineh M, Schueler-Furman O, Nitschke S, Minassian BA, Sadaka Y, Lerer I, Tabach Y, Meiner V Ann Clin Transl Neurol 2019 Jan 6 1 106-113
PI4K2A deficiency in an intellectual disability, epilepsy, myoclonus, akathisia syndrome.
Alkhater RA, Scherer SW, Minassian BA, Walker S Ann Clin Transl Neurol 2018 Dec 5 12 1617-1621
Optical coherence tomography features in brothers with aspartylglucosaminuria.
Goodspeed K, Harder L, Hughes S, Conger D, Taravella J, Gray SJ, Minassian B Ann Clin Transl Neurol 2018 Dec 5 12 1622-1626
Lafora Disease: A Review of Molecular Mechanisms and Pathology.
Verhalen B, Arnold S, Minassian BA Neuropediatrics 2018 Oct
Lafora disease - from pathogenesis to treatment strategies.
Nitschke F, Ahonen SJ, Nitschke S, Mitra S, Minassian BA Nat Rev Neurol 2018 Aug
Ocular phenotype and electroretinogram abnormalities in Lafora disease: A "window to the brain".
Vincent A, Macrì A, Tumber A, Koukas N, Ahonen S, Striano P, Minassian B, Neurology 2018 Jul 91 3 137-139
Extraneurological sparing in long-lived typical Lafora disease.
Goldsmith D, Minassian BA Epilepsia Open 2018 Jun 3 2 295-298
Chorea-acanthocytosis: Homozygous 1-kb deletion in VPS13A detected by whole-genome sequencing.
Walker S, Dad R, Thiruvahindrapuram B, Ullah MI, Ahmad A, Hassan MJ, Scherer SW, Minassian BA Neurol Genet 2018 Jun 4 3 e242
Global characterization of copy number variants in epilepsy patients from whole genome sequencing.
Monlong J, Girard SL, Meloche C, Cadieux-Dion M, Andrade DM, Lafreniere RG, Gravel M, Spiegelman D, Dionne-Laporte A, Boelman C, Hamdan FF, Michaud JL, Rouleau G, Minassian BA, Bourque G, Cossette P PLoS Genet. 2018 Apr 14 4 e1007285


Featured Books Legend Featured Books

The history of progressive myoclonus epilepsies. In Progressive Myoclonus Epilepsies: State-of-the-Art

Genton P, Striano P, Minassian BA (2017). Montrouge, France, John Libbey Eurotext

Honors & Awards

  • “Jacob's Ladder International Research Prize” for Outstanding Scientist
    Norman Saunders (2014)
  • Leadership Award in E-Infrastructure
    Ontario Research and Innovation Optical Network (ORION), in recognition of outstanding leadership in research and innovation in Ontario (2013)
  • Benjamin Boshes Memorial Lectureship, Keynote Speaker
    Israeli Neurological Association Annual Meeting (2011)
  • Canadian Paediatric Society Sanofi Pasteur Research Award
    For excellence in Canadian child health research (2008)
  • Dreifuss-Penry Epilepsy Award
    American Academy of Neurology, for Independent contribution to epilepsy research (2007)
  • Canada Research Chair in Pediatric Neurogenetics
  • John Stobo Prichard Award
    International Child Neurology Association (2006)
  • Ted Hall Award, Best Biology Paper
    Microscopy Society of America, Annual Meeting (2005)
  • Certificate of Appreciation
    International Rett Syndrome Association (2004)
  • Certificate of Appreciation
    Batten's Disease Research and Support Association (2002)
  • Certificate of Appreciation
    Canadian Angelman Syndrome Society (2002-2004)
  • Certificate of Appreciation
    Angelman Syndrome Foundation (1997)
  • Young Investigator Award
    American Epilepsy Society (1996)
  • Certificate of Appreciation
    Canadian Angleman Syndrome Society (1995-1998)
  • Gertrude and Charles Clark Cancer Research Fellow
    Jewish General Hospital, McGill University (1987)

Professional Associations/Affiliations

  • American Academy of Neurology
  • American Academy of Neurology, Neurogenetics Section - Founding Member
  • Canadian Medical Association
  • College of Physicians and Surgeons of Ontario
  • Ontario Medical Association
  • Royal College of Physicians and Surgeons Canada