Andrew DeVilbiss, Ph.D. Titles and Appointments Instructor Schools Medical School Departments Internal Medicine Biography Andrew DeVilbiss, Ph.D., is an Instructor in the Department of Internal Medicine at UT Southwestern Medical Center and a member of its Division of Hematology and Oncology. Dr. DeVilbiss holds dual bachelor's degrees in biochemestry and in cellular and molecular biology from the University of Wisconsin, La Crosse. He earned his doctorate from the University of Wisconsin, Madison, where he studied transcriptional and epigeneic mechansims regulating blood development and blood cancers. He then completed a postodoctoral fellowship at UT Southwestern Medical Center's Children's Research Institute, where he investigeted metabolic mechanisms that regulate hematopoietic stem cell maintenance and function. Dr. DeVilbiss research interests include transcriptional and metabolic mechanisms that facilitate drug resistance in multiple cancer types. Dr. DeVilbiss Joined the UT Southwestern Department of Internal Medicine faculty in 2024. Education Graduate School (2015) Graduate School Uni of Wisconsin-Madison (2015), Philosophy Research Interest Transcriptional and Metabolic Regulation of Cancer Growth and Metastasis Publications Differential Tumor Response Patterns and Extent of Necrosis After Immunotherapy Combinations Predict Clinical Responses for Renal Cell Carcinoma Issa W, Sayegh N, Gunenc D, Kaur N, DeVilbiss A, Abdullah S, Kapur P, Courtney K, Hammers H, Brugarolas J, Qin Q, Tachibana I, Lotan Y, Margulis V, Cadeddu J, Wang AZ, Zhang T Clinical Genitourinary Cancer 2026 Jun 24 Ovarian cancer cell glucocorticoid receptor activation increases myeloid-derived suppressor cell tumor infiltration Taya M, Gray E, Srivastava T, Chee WY, Fleming GF, DeVilbiss AW, Bennett LB, Conzen SD Endocrinology (United States) 2026 Apr 167 Single-Cell Profiling Reveals a Treg-Rich, NK Cell-Depleted Immune Microenvironment in Triple-Negative Breast Cancer with High-Glucocorticoid Receptor Expression Behar J, Shiang C, Dolcen DN, Bennett LB, DeVilbiss AW, Matossian MD, Chan IS, Nanda R, Conzen SD, Lafin JT Breast Cancer: Targets and Therapy 2026 18 Molecular changes in advanced clear cell renal cell carcinoma (ccRCC) pre- and post-immunotherapy. Issa W, Kaur N, DeVilbiss A, Yu Z, Nielsen AW, Zhong H, Gunenc D, Zhou Q, Jasti J, Kapur P, Rajaram S, Xing C, Jia L, Wang AZ, Zhang T Journal of Clinical Oncology 2025 Jun 43 e16533-e16533 Ascorbate deficiency increases quiescence and self-renewal in hematopoietic stem cells and multipotent progenitors Comazzetto S, Cassidy DL, DeVilbiss AW, Jeffery EC, Ottesen BR, Reyes AR, Paul A, Bansal S, Xie SZ, Muh S, Mathews TP, Chen B, Zhao Z, Morrison SJ Blood 2025 Jan 145 114-126 Failure of metabolic checkpoint control during late-stage granulopoiesis drives neutropenia in reticular dysgenesis Wang W, Arreola M, Mathews T, DeVilbiss A, Zhao Z, Martin-Sandoval M, Mohammed A, Benegiamo G, Awani A, Goeminne L, Dever D, Nakauchi Y, Porteus MH, Pavel-Dinu M, Al-Herz W, Auwerx J, Morrison SJ, Weinacht KG Blood 2024 Dec 144 2718-2734 The redox sensor KEAP1 facilitates adaptation of T cells to chronic antigen stimulation by preventing hyperactivation Zhu Z, Luo Y, Lou G, Yihunie K, Wizzard S, DeVilbiss AW, Muh S, Ma C, Shinde SS, Hoar J, Hu T, Zhang N, Biswal S, DeBerardinis RJ, Wu T, Yao C Science Immunology 2024 Nov 9 Autophagy counters inflammation-driven glycolytic impairment in aging hematopoietic stem cells Dellorusso PV, Proven MA, Calero-Nieto FJ, Wang X, Mitchell CA, Hartmann F, Amouzgar M, Favaro P, DeVilbiss A, Swann JW, Ho TT, Zhao Z, Bendall SC, Morrison S, Göttgens B, Passegué E Cell Stem Cell 2024 Jul 31 1020-1037.e9 Metabolic regulation of somatic stem cells in vivo Meacham CE, DeVilbiss AW, Morrison SJ Nature Reviews Molecular Cell Biology 2022 Jun 23 428-443 BMAL1 drives muscle repair through control of hypoxic NAD+ regeneration in satellite cells Zhu P, Hamlish NX, Thakkar AV, Steffeck AW, Rendleman EJ, Khan NH, Waldeck NJ, DeVilbiss AW, Martin-Sandoval MS, Mathews TP, Chandel NS, Peek CB Genes and Development 2022 Feb 36 149-166 Results 1-10 of 18 1 2 Next Last Honors & Awards Collaborator of the YearUT Southwestern Medical Center Children's Research Institute (2021) Postdoctoral Certificate in Scientific ManagementUT Southwestern Graduate School of Biomedical Sciences (2019) Postdoctoral Certificate in ResearchUT Southwestern Medical Center (2017) Ruth L. Kirschstein National Research Service Award Fellowship(NIH F32) (2017-2020)
