Dr. Ross’s research focuses on how cells receive, amplify, integrate, and sort information. The work focuses on the integrated control of cellular signaling pathways, particularly those that involve GTP-binding proteins.
- University of California-Davis (1970), Biochemistry
- Graduate School
- Cornell University (1975), Biochemistry
- Computational modeling of signaling networks
- Integration of biological signaling
- Interaction of membrane-bound enzymes and hormone receptors
- Mechanisms of G protein-mediated signal transduction
- Structure of G protein-coupled receptors
- Expression of human muscarinic cholinergic receptors in tobacco.
- Mu JH, Chua NH, Ross EM Plant Mol. Biol. 1997 May 34 2 357-62
- A Gs-selective analog of the receptor-mimetic peptide mastoparan binds to Gs alpha in a kinked helical conformation.
- Sukumar M, Ross EM, Higashijima T Biochemistry 1997 Mar 36 12 3632-9
- A GTPase-activating protein for the G protein Galphaz. Identification, purification, and mechanism of action.
- Wang J, Tu Y, Woodson J, Song X, Ross EM J. Biol. Chem. 1997 Feb 272 9 5732-40
- Carboxyl-terminal fragments of phospholipase C-beta1 with intrinsic Gq GTPase-activating protein (GAP) activity.
- Paulssen RH, Woodson J, Liu Z, Ross EM J. Biol. Chem. 1996 Oct 271 43 26622-9
- Purification and characterization of phospholipase C-beta 1 mutants expressed in E. coli.
- Meij JT, Ross EM Biochem. Biophys. Res. Commun. 1996 Aug 225 3 705-11
- Functional importance of the amino terminus of Gq alpha.
- Hepler JR, Biddlecome GH, Kleuss C, Camp LA, Hofmann SL, Ross EM, Gilman AG J. Biol. Chem. 1996 Jan 271 1 496-504
- The carboxyl-terminal anchorage domain of the turkey beta 1-adrenergic receptor is encoded by an alternatively spliced exon.
- Wang J, Ross EM J. Biol. Chem. 1995 Mar 270 12 6488-95
- Carboxyl-terminal domains in the avian beta 1-adrenergic receptor that regulate agonist-promoted endocytosis.
- Parker EM, Swigart P, Nunnally MH, Perkins JP, Ross EM J. Biol. Chem. 1995 Mar 270 12 6482-7
- Protein modification. Palmitoylation in G-protein signaling pathways.
- Ross EM Curr. Biol. 1995 Feb 5 2 107-9
- G protein GTPase-activating proteins: regulation of speed, amplitude, and signaling selectivity.
- Ross EM Recent Prog. Horm. Res. 1995 50 207-21
Honors & Awards
- NIGMS MERIT Award
- ASPET Goodman and Gilman Award for Drug-Receptor Pharmacology
- Chairman, Gordon Research Conference on Molecular Pharmacology
- Scientific Director, NATO/FEBS Adv. Study Inst. on Biological Signal Transduction
- American Society for Biochemistry and Molecular Biology
- American Society for Pharmacology and Experimental Therapeutics (Section on Molecular Pharmacology)
- Biophysical Society