Biography

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Dr. Rosenfeld attended college at Emory University and graduated from Emory University School of Medicine. He completed his general training in Pediatrics at Yale-New Haven Medical Center and Albert Einstein College of Medicine, where he also was Chief Resident. He then spent a year as a Pediatric Pulmonary Fellow with Amile Scarpelli, MD, PhD at Albert Einstein, followed by 2 years in the Perinatal Research Program at the University of Colorado Health Sciences Center under the mentoring of Frederick Battaglia, MD and Giacomo Meschia, MD. After joining the faculty at UT Southwestern in 1973, Dr. Rosenfeld established a perinatal biology laboratory for the study of cardiovascular changes in pregnancy, and in particular, the study of uteroplacental and umbilicoplacental blood flows. He has received nearly continuous funding from NIH for his studies of the mother and fetus for 39 years, as well as other grants, making contributions to our understanding of cardiovascular changes in pregnancy and during fetal and neonatal development. He was the Director of the Division of Neonatal-Perinatal Medicine for nearly 35 years and has provided research training and mentoring for more than 15 fellows in his specialty, 5 in Maternal-Fetal Medicine, and numerous postdoctoral and medical students. His publication record exceeds 200 peer-reviewed articles and chapters in several textbooks. Dr. Rosenfeld was the 2005 recipient of the Founders Award given by the Southern Society for Pediatric Research for his research contributions to child health and was elected a Fellow in the Section of Heart and Circulatory Physiology, American Physiological Society in 2005. He received a 2018 Albert Nelson Marquis Lifetime Achievement Award and was awarded Emeritus by the University of Texas March 2019.

Education

Medical School
Emory University (1966)

Research Interest

  • Blood pressure regulation before and after birth
  • Cardiovascular role of estrogen in pregnancy
  • Development of the renin-angiotensin system
  • Mechanisms modulating uteroplacental blood flow

Publications

Featured Publications LegendFeatured Publications

Lenticulostriate vasculopathy in neonates: Perspective of the radiologist.
Koral K, Sisman J, Pritchard M, Rosenfeld CR Early Hum. Dev. 2015 Jul 91 7 431-5
Lenticulostriate vasculopathy in neonates: Is it a marker of cerebral insult? Critical review of the literature.
Sisman J, Rosenfeld CR Early Hum. Dev. 2015 Jul 91 7 423-6
Maternal high fat diet is associated with impaired fetal lung development.
Mayor RS, Finch KE, Zehr J, Morselli E, Neinast MD, Frank AP, Hahner LD, Wang J, Rakheja D, Palmer BF, Rosenfeld CR, Savani RC, Clegg DJ Am. J. Physiol. Lung Cell Mol. Physiol. 2015 Jun ajplung.00105.2015
Estrogen Replacement Therapy in Ovariectomized Nonpregnant Ewes Stimulates Uterine Artery Hydrogen Sulfide Biosynthesis by Selectively Upregulating Cystathionine ß Synthase Expression.
Lechuga TJ, Zhang H, Sheibani L, Karim M, Jia J, Magness RR, Rosenfeld CR, Chen DB Endocrinology 2015 Mar en20151086
Prolonged Uterine Artery Nitric Oxide Synthase Inhibition Modestly Alters Basal Uteroplacental Vasodilation in the Last Third of Ovine Pregnancy.
Rosenfeld CR, Roy T Am. J. Physiol. Heart Circ. Physiol. 2014 Aug
Biomarkers for severity of neonatal hypoxic-ischemic encephalopathy and outcomes in newborns receiving hypothermia therapy.
Chalak LF, Sánchez PJ, Adams-Huet B, Laptook AR, Heyne RJ, Rosenfeld CR J. Pediatr. 2014 Mar 164 3 468-474.e1
Serial neutrophil values facilitate predicting the absence of neonatal early-onset sepsis.
Mikhael M, Brown LS, Rosenfeld CR J. Pediatr. 2014 Mar 164 3 522-528.e3
Neurodevelopmental outcomes of extremely low birth weight infants with spontaneous intestinal perforation or surgical necrotizing enterocolitis.
Wadhawan R, Oh W, Hintz SR, Blakely ML, Das A, Bell EF, Saha S, Laptook AR, Shankaran S, Stoll BJ, Walsh MC, Higgins RD J Perinatol 2014 Jan 34 1 64-70
Immunogenicity of Haemophilus influenzae Type b Protein Conjugate Vaccines in Very Low Birth Weight Infants.
D'Angio CT, Murray TE, Li L, Heyne RJ, O'Shea TM, Schelonka RL, Shankaran S, Duara S, Goldberg RN, Stoll BJ, Stevenson DK, Vohr BR, Phelps DL, Carlo WA, Pichichero ME, Das A, Higgins RD Pediatr. Infect. Dis. J. 2013 Dec 32 12 1400-2
Apgar scores at 10 min and outcomes at 6-7 years following hypoxic-ischaemic encephalopathy.
Natarajan G, Shankaran S, Laptook AR, Pappas A, Bann CM, McDonald SA, Das A, Higgins RD, Hintz SR, Vohr BR Arch. Dis. Child. Fetal Neonatal Ed. 2013 Nov 98 6 F473-9

Books

Featured Books Legend Featured Books

Honors & Awards

  • Albert Nelson Marquis Lifetime Achievement Award
    Marquis Who's Who Publications Board (2018)
  • Top Doctors
    Castle Connolly Medical Ltd. (2014)
  • Top Doctors
    US News & World Report (2012)
  • Student Teaching Award, Senior Acute Care Medicine
    UT Southwestern Medical School (2008)
  • Legends Award for Outstanding Service
    Parkland Memorial Hospital (2007)
  • SSPR Founders Award
    Recognition for research contributing to improving child health, Southern Society of Pediatric Research (2005)
  • Who's Who in America
    (2005)
  • Associate Editor, Reproductive Sciences (JSGI)
    Appointed to the initial Editorial Board; evaluating basic research (1993-2018)
  • George L. MacGregor Professorship of Pediatrics
    Recognition for research contributions in Perinatal Medicine (1993-2019)
  • Associate Editor, Early Human Development
    Responsible for all manuscripts in the Americas (1986)
  • Perinatal Research Society
    Recognition for contributions to studies in pregnancy and development (1981)

Professional Associations/Affiliations

  • American Pediatric Program Directors (2008-2010)
  • American Heart Association (1999-2019)
  • American Physiologic Society (1985-2019)
  • American Pediatric Society (1983)
  • Perinatal Research Society (1981)
  • Society for Gynecologic Investigation (1978)
  • Society for Pediatric Research (1977)
  • American Academy of Pediatrics (1976)