Biography

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Dr. Rosenfeld attended college at Emory University and graduated from Emory University School of Medicine. He completed his general training in Pediatrics at Yale-New Haven Medical Center and Albert Einstein College of Medicine, where he also was Chief Resident. He then spent a year as a Pediatric Pulmonary Fellow with Amile Scarpelli, MD, PhD at Albert Einstein, followed by 2 years in the Perinatal Research Program at the University of Colorado Health Sciences Center under the mentoring of Frederick Battaglia, MD and Giacomo Meschia, MD. After joining the faculty at UT Southwestern in 1973, Dr. Rosenfeld established a perinatal biology laboratory for the study of cardiovascular changes in pregnancy, and in particular, the study of uteroplacental and umbilicoplacental blood flows. He has received nearly continuous funding from NIH for his studies of the mother and fetus for 39 years, as well as other grants, making contributions to our understanding of cardiovascular changes in pregnancy and during fetal and neonatal development. He was the Director of the Division of Neonatal-Perinatal Medicine for nearly 35 years and has provided research training and mentoring for more than 15 fellows in his specialty, 5 in Maternal-Fetal Medicine, and numerous postdoctoral and medical students. His publication record exceeds 200 peer-reviewed articles and chapters in several textbooks. Dr. Rosenfeld was the 2005 recipient of the Founders Award given by the Southern Society for Pediatric Research for his research contributions to child health and was elected a Fellow in the Section of Heart and Circulatory Physiology, American Physiological Society in 2005. He received a 2018 Albert Nelson Marquis Lifetime Achievement Award and was awarded Emeritus by the University of Texas March 2019.

Education

Medical School
Emory University (1966)

Research Interest

  • Blood pressure regulation before and after birth
  • Cardiovascular role of estrogen in pregnancy
  • Development of the renin-angiotensin system
  • Mechanisms modulating uteroplacental blood flow

Publications

Featured Publications LegendFeatured Publications

Differential development of umbilical and systemic arteries. II. Contractile proteins.
Arens Y, Chapados RA, Cox BE, Kamm KE, Rosenfeld CR Am. J. Physiol. 1998 Jun 274 6 Pt 2 R1815-23
Differential development of umbilical and systemic arteries. I. ANG II receptor subtype expression.
Kaiser JR, Cox BE, Roy TA, Rosenfeld CR Am. J. Physiol. 1998 Mar 274 3 Pt 2 R797-807
Estrogen acutely stimulates nitric oxide synthase activity in fetal pulmonary artery endothelium.
Lantin-Hermoso RL, Rosenfeld CR, Yuhanna IS, German Z, Chen Z, Shaul PW Am. J. Physiol. 1997 Jul 273 1 Pt 1 L119-26
Circulating neutrophils in septic preterm neonates: comparison of two reference ranges.
Engle WD, Rosenfeld CR, Mouzinho A, Risser RC, Zeray F, Sanchez PJ Pediatrics 1997 Mar 99 3 E10
Nitric oxide contributes to estrogen-induced vasodilation of the ovine uterine circulation.
Rosenfeld CR, Cox BE, Roy T, Magness RR J. Clin. Invest. 1996 Nov 98 9 2158-66
Brain does not utilize low density lipoprotein-cholesterol during fetal and neonatal development in the sheep.
Turley SD, Burns DK, Rosenfeld CR, Dietschy JM J. Lipid Res. 1996 Sep 37 9 1953-61
Alterations in myometrial stress during ovine pregnancy and the puerperium.
Ipson MA, Rosenfeld CR, Magness RR, Kamm KE Am. J. Physiol. 1996 Aug 271 2 Pt 2 R446-54
Tissue specific expression of vascular smooth muscle angiotensin II receptor subtypes during ovine pregnancy.
Cox BE, Rosenfeld CR, Kalinyak JE, Magness RR, Shaul PW Am. J. Physiol. 1996 Jul 271 1 Pt 2 H212-21
Endothelial vasodilator production by uterine and systemic arteries. I. Effects of ANG II on PGI2 and NO in pregnancy.
Magness RR, Rosenfeld CR, Hassan A, Shaul PW Am. J. Physiol. 1996 Jun 270 6 Pt 2 H1914-23
Angiotensin II receptor characteristics and subtype expression in uterine arteries and myometrium during pregnancy.
Cox BE, Word RA, Rosenfeld CR J. Clin. Endocrinol. Metab. 1996 Jan 81 1 49-58

Books

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Honors & Awards

  • Albert Nelson Marquis Lifetime Achievement Award
    Marquis Who's Who Publications Board (2018)
  • Top Doctors
    Castle Connolly Medical Ltd. (2014)
  • Top Doctors
    US News & World Report (2012)
  • Student Teaching Award, Senior Acute Care Medicine
    UT Southwestern Medical School (2008)
  • Legends Award for Outstanding Service
    Parkland Memorial Hospital (2007)
  • SSPR Founders Award
    Recognition for research contributing to improving child health, Southern Society of Pediatric Research (2005)
  • Who's Who in America
    (2005)
  • Associate Editor, Reproductive Sciences (JSGI)
    Appointed to the initial Editorial Board; evaluating basic research (1993-2018)
  • George L. MacGregor Professorship of Pediatrics
    Recognition for research contributions in Perinatal Medicine (1993-2019)
  • Associate Editor, Early Human Development
    Responsible for all manuscripts in the Americas (1986)
  • Perinatal Research Society
    Recognition for contributions to studies in pregnancy and development (1981)

Professional Associations/Affiliations

  • American Pediatric Program Directors (2008-2010)
  • American Heart Association (1999-2019)
  • American Physiologic Society (1985-2019)
  • American Pediatric Society (1983)
  • Perinatal Research Society (1981)
  • Society for Gynecologic Investigation (1978)
  • Society for Pediatric Research (1977)
  • American Academy of Pediatrics (1976)