Biography

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Dr. Rosenfeld attended college at Emory University and graduated from Emory University School of Medicine. He completed his general training in Pediatrics at Yale-New Haven Medical Center and Albert Einstein College of Medicine, where he also was Chief Resident. He then spent a year as a Pediatric Pulmonary Fellow with Amile Scarpelli, MD, PhD at Albert Einstein, followed by 2 years in the Perinatal Research Program at the University of Colorado Health Sciences Center under the mentoring of Frederick Battaglia, MD and Giacomo Meschia, MD. After joining the faculty at UT Southwestern in 1973, Dr. Rosenfeld established a perinatal biology laboratory for the study of cardiovascular changes in pregnancy, and in particular, the study of uteroplacental and umbilicoplacental blood flows. He has received nearly continuous funding from NIH for his studies of the mother and fetus for 39 years, as well as other grants, making contributions to our understanding of cardiovascular changes in pregnancy and during fetal and neonatal development. He was the Director of the Division of Neonatal-Perinatal Medicine for nearly 35 years and has provided research training and mentoring for more than 15 fellows in his specialty, 5 in Maternal-Fetal Medicine, and numerous postdoctoral and medical students. His publication record exceeds 200 peer-reviewed articles and chapters in several textbooks. Dr. Rosenfeld was the 2005 recipient of the Founders Award given by the Southern Society for Pediatric Research for his research contributions to child health and was elected a Fellow in the Section of Heart and Circulatory Physiology, American Physiological Society in 2005. He received a 2018 Albert Nelson Marquis Lifetime Achievement Award and was awarded Emeritus by the University of Texas March 2019.

Education

Medical School
Emory University (1966)

Research Interest

  • Blood pressure regulation before and after birth
  • Cardiovascular role of estrogen in pregnancy
  • Development of the renin-angiotensin system
  • Mechanisms modulating uteroplacental blood flow

Publications

Featured Publications LegendFeatured Publications

Estrogen selectively up-regulates eNOS and nNOS in reproductive arteries by transcriptional mechanisms.
Rosenfeld CR, Chen C, Roy T, Liu X J. Soc. Gynecol. Investig. 2003 May 10 4 205-15
Differential responses to systemic and local angiotensin II infusions in conscious postnatal sheep.
Velaphi SC, Roy T, Despain K, Rosenfeld CR Pediatr. Res. 2002 Sep 52 3 333-41
Mechanisms modulating estrogen-induced uterine vasodilation.
Rosenfeld CR, Roy T, Cox BE Vascul. Pharmacol. 2002 Feb 38 2 115-25
Maturation of ovine uterine smooth muscle during development and the effects of parity.
Arens Y, Kamm KE, Rosenfeld CR J. Soc. Gynecol. Investig. 2000 Sep-Oct 7 5 284-90
Calcium-activated potassium channels and nitric oxide coregulate estrogen-induced vasodilation.
Rosenfeld CR, White RE, Roy T, Cox BE Am. J. Physiol. Heart Circ. Physiol. 2000 Jul 279 1 H319-28
Determinants of blood pressure in very low birth weight neonates: lack of effect of antenatal steroids.
LeFlore JL, Engle WD, Rosenfeld CR Early Hum. Dev. 2000 Jul 59 1 37-50
Regulation of types I and III NOS in ovine uterine arteries by daily and acute estrogen exposure.
Salhab WA, Shaul PW, Cox BE, Rosenfeld CR Am. J. Physiol. Heart Circ. Physiol. 2000 Jun 278 6 H2134-42
Maturational differences between vascular and bladder smooth muscle during ovine development.
Arens YH, Rosenfeld CR, Kamm KE Am. J. Physiol. Regul. Integr. Comp. Physiol. 2000 May 278 5 R1305-13
Angiotensin II indirectly vasoconstricts the ovine uterine circulation.
Cox BE, Williams CE, Rosenfeld CR Am. J. Physiol. Regul. Integr. Comp. Physiol. 2000 Feb 278 2 R337-44
A population-based study of congenital diaphragmatic hernia: impact of associated anomalies and preoperative blood gases on survival.
Kaiser JR, Rosenfeld CR J. Pediatr. Surg. 1999 Aug 34 8 1196-202

Books

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Honors & Awards

  • Albert Nelson Marquis Lifetime Achievement Award
    Marquis Who's Who Publications Board (2018)
  • Top Doctors
    Castle Connolly Medical Ltd. (2014)
  • Top Doctors
    US News & World Report (2012)
  • Student Teaching Award, Senior Acute Care Medicine
    UT Southwestern Medical School (2008)
  • Legends Award for Outstanding Service
    Parkland Memorial Hospital (2007)
  • SSPR Founders Award
    Recognition for research contributing to improving child health, Southern Society of Pediatric Research (2005)
  • Who's Who in America
    (2005)
  • Associate Editor, Reproductive Sciences (JSGI)
    Appointed to the initial Editorial Board; evaluating basic research (1993-2018)
  • George L. MacGregor Professorship of Pediatrics
    Recognition for research contributions in Perinatal Medicine (1993-2019)
  • Associate Editor, Early Human Development
    Responsible for all manuscripts in the Americas (1986)
  • Perinatal Research Society
    Recognition for contributions to studies in pregnancy and development (1981)

Professional Associations/Affiliations

  • American Pediatric Program Directors (2008-2010)
  • American Heart Association (1999-2019)
  • American Physiologic Society (1985-2019)
  • American Pediatric Society (1983)
  • Perinatal Research Society (1981)
  • Society for Gynecologic Investigation (1978)
  • Society for Pediatric Research (1977)
  • American Academy of Pediatrics (1976)