Biography

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Dr. Rosenfeld attended college at Emory University and graduated from Emory University School of Medicine. He completed his general training in Pediatrics at Yale-New Haven Medical Center and Albert Einstein College of Medicine, where he also was Chief Resident. He then spent a year as a Pediatric Pulmonary Fellow with Amile Scarpelli, MD, PhD at Albert Einstein, followed by 2 years in the Perinatal Research Program at the University of Colorado Health Sciences Center under the mentoring of Frederick Battaglia, MD and Giacomo Meschia, MD. After joining the faculty at UT Southwestern in 1973, Dr. Rosenfeld established a perinatal biology laboratory for the study of cardiovascular changes in pregnancy, and in particular, the study of uteroplacental and umbilicoplacental blood flows. He has received nearly continuous funding from NIH for his studies of the mother and fetus for 39 years, as well as other grants, making contributions to our understanding of cardiovascular changes in pregnancy and during fetal and neonatal development. He was the Director of the Division of Neonatal-Perinatal Medicine for nearly 35 years and has provided research training and mentoring for more than 15 fellows in his specialty, 5 in Maternal-Fetal Medicine, and numerous postdoctoral and medical students. His publication record exceeds 200 peer-reviewed articles and chapters in several textbooks. Dr. Rosenfeld was the 2005 recipient of the Founders Award given by the Southern Society for Pediatric Research for his research contributions to child health and was elected a Fellow in the Section of Heart and Circulatory Physiology, American Physiological Society in 2005. He received a 2018 Albert Nelson Marquis Lifetime Achievement Award and was awarded Emeritus by the University of Texas March 2019.

Education

Medical School
Emory University (1966)

Research Interest

  • Blood pressure regulation before and after birth
  • Cardiovascular role of estrogen in pregnancy
  • Development of the renin-angiotensin system
  • Mechanisms modulating uteroplacental blood flow

Publications

Featured Publications LegendFeatured Publications

Vascular development in early ovine gestation: carotid smooth muscle function, phenotype, and biochemical markers.
Hutanu C, Cox BE, DeSpain K, Liu XT, Rosenfeld CR Am. J. Physiol. Regul. Integr. Comp. Physiol. 2007 Jul 293 1 R323-33
The renin-angiotensin system in conscious newborn sheep: metabolic clearance rate and activity.
Velaphi SC, Despain K, Roy T, Rosenfeld CR Pediatr. Res. 2007 Jun 61 6 681-6
Prevalence of spontaneous closure of the ductus arteriosus in neonates at a birth weight of 1000 grams or less.
Koch J, Hensley G, Roy L, Brown S, Ramaciotti C, Rosenfeld CR Pediatrics 2006 Apr 117 4 1113-21
Estrogen regulates {beta}1-subunit expression in Ca(2+)-activated K(+) channels in arteries from reproductive tissues.
Nagar D, Liu XT, Rosenfeld CR Am. J. Physiol. Heart Circ. Physiol. 2005 Oct 289 4 H1417-27
Large-conductance Ca2+-dependent K+ channels regulate basal uteroplacental blood flow in ovine pregnancy.
Rosenfeld CR, Roy T, DeSpain K, Cox BE J. Soc. Gynecol. Investig. 2005 Sep 12 6 402-8
Effects of systemic and local phenylephrine and arginine vasopressin infusions in conscious postnatal sheep.
Velaphi SC, Roy T, Despain K, Rosenfeld CR Pediatr. Res. 2005 Jul 58 1 58-65
Vessel-specific regulation of angiotensin II receptor subtypes during ovine development.
Cox BE, Liu XT, Fluharty SJ, Rosenfeld CR Pediatr. Res. 2005 Jan 57 1 124-32
Angiotensin II mediates uterine vasoconstriction through alpha-stimulation.
Cox BE, Roy TA, Rosenfeld CR Am. J. Physiol. Heart Circ. Physiol. 2004 Jul 287 1 H126-34
Hospital survival of very-low-birth-weight neonates from 1977 to 2000.
Kaiser JR, Tilford JM, Simpson PM, Salhab WA, Rosenfeld CR J Perinatol 2004 Jun 24 6 343-50
Are complete blood cell counts useful in the evaluation of asymptomatic neonates exposed to suspected chorioamnionitis?
Jackson GL, Engle WD, Sendelbach DM, Vedro DA, Josey S, Vinson J, Bryant C, Hahn G, Rosenfeld CR Pediatrics 2004 May 113 5 1173-80

Books

Featured Books Legend Featured Books

Honors & Awards

  • Albert Nelson Marquis Lifetime Achievement Award
    Marquis Who's Who Publications Board (2018)
  • Top Doctors
    Castle Connolly Medical Ltd. (2014)
  • Top Doctors
    US News & World Report (2012)
  • Student Teaching Award, Senior Acute Care Medicine
    UT Southwestern Medical School (2008)
  • Legends Award for Outstanding Service
    Parkland Memorial Hospital (2007)
  • SSPR Founders Award
    Recognition for research contributing to improving child health, Southern Society of Pediatric Research (2005)
  • Who's Who in America
    (2005)
  • Associate Editor, Reproductive Sciences (JSGI)
    Appointed to the initial Editorial Board; evaluating basic research (1993-2018)
  • George L. MacGregor Professorship of Pediatrics
    Recognition for research contributions in Perinatal Medicine (1993-2019)
  • Associate Editor, Early Human Development
    Responsible for all manuscripts in the Americas (1986)
  • Perinatal Research Society
    Recognition for contributions to studies in pregnancy and development (1981)

Professional Associations/Affiliations

  • American Pediatric Program Directors (2008-2010)
  • American Heart Association (1999-2019)
  • American Physiologic Society (1985-2019)
  • American Pediatric Society (1983)
  • Perinatal Research Society (1981)
  • Society for Gynecologic Investigation (1978)
  • Society for Pediatric Research (1977)
  • American Academy of Pediatrics (1976)