Dr. Rosenfeld attended college at Emory University and graduated from Emory University School of Medicine. He completed his general training in Pediatrics at Yale-New Haven Medical Center and Albert Einstein College of Medicine, where he also was Chief Resident. He then spent a year as a Pediatric Pulmonary Fellow with Amile Scarpelli, MD, PhD at Albert Einstein, followed by 2 years in the Perinatal Research Program at the University of Colorado Health Sciences Center under the mentoring of Frederick Battaglia, MD and Giacomo Meschia, MD. After joining the faculty at UT Southwestern in 1973, Dr. Rosenfeld established a perinatal biology laboratory for the study of cardiovascular changes in pregnancy, and in particular, the study of uteroplacental and umbilicoplacental blood flows. He has received nearly continuous funding from NIH for his studies of the mother and fetus for 39 years, as well as other grants, making contributions to our understanding of cardiovascular changes in pregnancy and during fetal and neonatal development. He was the Director of the Division of Neonatal-Perinatal Medicine for nearly 35 years and has provided research training and mentoring for more than 15 fellows in his specialty, 5 in Maternal-Fetal Medicine, and numerous postdoctoral and medical students. His publication record exceeds 200 peer-reviewed articles and chapters in several textbooks. Dr. Rosenfeld was the 2005 recipient of the Founders Award given by the Southern Society for Pediatric Research for his research contributions to child health and was elected a Fellow in the Section of Heart and Circulatory Physiology, American Physiological Society in 2005. He received a 2018 Albert Nelson Marquis Lifetime Achievement Award and was awarded Emeritus by the University of Texas March 2019.
- Medical School
- Emory University (1966)
- Blood pressure regulation before and after birth
- Cardiovascular role of estrogen in pregnancy
- Development of the renin-angiotensin system
- Mechanisms modulating uteroplacental blood flow
- Early-childhood neurodevelopmental outcomes are not improving for infants born at <25 weeks' gestational age.
- Hintz SR, Kendrick DE, Wilson-Costello DE, Das A, Bell EF, Vohr BR, Higgins RD Pediatrics 2011 Jan 127 1 62-70
- Intercenter differences in bronchopulmonary dysplasia or death among very low birth weight infants.
- Ambalavanan N, Walsh M, Bobashev G, Das A, Levine B, Carlo WA, Higgins RD Pediatrics 2011 Jan 127 1 e106-16
- Prenatal closure of the ductus arteriosus and maternal ingestion of anthocyanins.
- Kapadia V, Embers D, Wells E, Lemler M, Rosenfeld CR J Perinatol 2010 Apr 30 4 291-4
- Regulation of the cGMP-cPKG pathway and large-conductance Ca2+-activated K+ channels in uterine arteries during the ovine ovarian cycle.
- Khan LH, Rosenfeld CR, Liu XT, Magness RR Am. J. Physiol. Endocrinol. Metab. 2010 Feb 298 2 E222-8
- Maternal age, multiple birth, and extremely low birth weight infants.
- Vohr BR, Tyson JE, Wright LL, Perritt RL, Li L, Poole WK J. Pediatr. 2009 Apr 154 4 498-503.e2
- Interrater reliability and effect of state on blood pressure measurements in infants 1 to 3 years of age.
- Duncan AF, Rosenfeld CR, Morgan JS, Ahmad N, Heyne RJ Pediatrics 2008 Sep 122 3 e590-4
- Metabolism and synthesis of arginine vasopressin in conscious newborn sheep.
- Miao DC, Velaphi SC, Roy T, Despain K, Rosenfeld CR Am. J. Physiol. Endocrinol. Metab. 2008 Sep 295 3 E672-7
- Large conductance Ca2+-activated K+ channels contribute to vascular function in nonpregnant human uterine arteries.
- Rosenfeld CR, Word RA, DeSpain K, Liu XT Reprod Sci 2008 Sep 15 7 651-60
- Meconium increases type 1 angiotensin II receptor expression and alveolar cell death.
- Rosenfeld CR, Zagariya AM, Liu XT, Willis BC, Fluharty S, Vidyasagar D Pediatr. Res. 2008 Mar 63 3 251-6
- Insulin resistance in Hispanic large-for-gestational-age neonates at birth.
- Dyer JS, Rosenfeld CR, Rice J, Rice M, Hardin DS J. Clin. Endocrinol. Metab. 2007 Oct 92 10 3836-43
Regulation of the Placental Circulation. In Polin RA, Abman SH, Rowitch D, Benitz WE, eds. Fetal and Neonatal Physiology. 5th ed.
Rosenfeld CR. (2016). Philadelphia: Elsevier; 114-120.
Maternal Cardiovascular Alterations during Pregnancy. In Gluckman PS, Heymann MA, eds. Perinatal and Pediatric Pathophysiology: A Clinical Perspective.
Magness RR, Rosenfeld CR. (1993). London: Edward Arnold Publisher.
Eicosanoids and the Regulation of Uteroplacental Hemodynamics. In Mitchell MD, ed. Eicosanoids in Reproduction
Magness RR, Rosenfeld CR. (1990). CRC Press; 139-168.
Honors & Awards
- Albert Nelson Marquis Lifetime Achievement Award
Marquis Who's Who Publications Board (2018)
- Top Doctors
Castle Connolly Medical Ltd. (2014)
- Top Doctors
US News & World Report (2012)
- Student Teaching Award, Senior Acute Care Medicine
UT Southwestern Medical School (2008)
- Legends Award for Outstanding Service
Parkland Memorial Hospital (2007)
- SSPR Founders Award
Recognition for research contributing to improving child health, Southern Society of Pediatric Research (2005)
- Who's Who in America
- Associate Editor, Reproductive Sciences (JSGI)
Appointed to the initial Editorial Board; evaluating basic research (1993-2018)
- George L. MacGregor Professorship of Pediatrics
Recognition for research contributions in Perinatal Medicine (1993-2019)
- Associate Editor, Early Human Development
Responsible for all manuscripts in the Americas (1986)
- Perinatal Research Society
Recognition for contributions to studies in pregnancy and development (1981)
- American Pediatric Program Directors (2008-2010)
- American Heart Association (1999-2019)
- American Physiologic Society (1985-2019)
- American Pediatric Society (1983)
- Perinatal Research Society (1981)
- Society for Gynecologic Investigation (1978)
- Society for Pediatric Research (1977)
- American Academy of Pediatrics (1976)