Dr. Rosenfeld attended college at Emory University and graduated from Emory University School of Medicine. He completed his general training in Pediatrics at Yale-New Haven Medical Center and Albert Einstein College of Medicine, where he also was Chief Resident. He then spent a year as a Pediatric Pulmonary Fellow with Amile Scarpelli, MD, PhD at Albert Einstein, followed by 2 years in the Perinatal Research Program at the University of Colorado Health Sciences Center under the mentoring of Frederick Battaglia, MD and Giacomo Meschia, MD. After joining the faculty at UT Southwestern in 1973, Dr. Rosenfeld established a perinatal biology laboratory for the study of cardiovascular changes in pregnancy, and in particular, the study of uteroplacental and umbilicoplacental blood flows. He has received nearly continuous funding from NIH for his studies of the mother and fetus for 39 years, as well as other grants, making contributions to our understanding of cardiovascular changes in pregnancy and during fetal and neonatal development. He was the Director of the Division of Neonatal-Perinatal Medicine for nearly 35 years and has provided research training and mentoring for more than 15 fellows in his specialty, 5 in Maternal-Fetal Medicine, and numerous postdoctoral and medical students. His publication record exceeds 200 peer-reviewed articles and chapters in several textbooks. Dr. Rosenfeld was the 2005 recipient of the Founders Award given by the Southern Society for Pediatric Research for his research contributions to child health and was elected a Fellow in the Section of Heart and Circulatory Physiology, American Physiological Society in 2005. He received a 2018 Albert Nelson Marquis Lifetime Achievement Award and was awarded Emeritus by the University of Texas March 2019.
- Medical School
- Emory University (1966)
- Blood pressure regulation before and after birth
- Cardiovascular role of estrogen in pregnancy
- Development of the renin-angiotensin system
- Mechanisms modulating uteroplacental blood flow
- Early Sepsis Does Not Increase the Risk of Late Sepsis in Very Low Birth Weight Neonates.
- Wynn JL, Hansen NI, Das A, Cotten CM, Goldberg RN, Sánchez PJ, Bell EF, Van Meurs KP, Carlo WA, Laptook AR, Higgins RD, Benjamin DK, Stoll BJ J. Pediatr. 2013 Jan
- Elevated temperature and 6- to 7-year outcome of neonatal encephalopathy.
- Laptook AR, McDonald SA, Shankaran S, Stephens BE, Vohr BR, Guillet R, Higgins RD, Das A Ann. Neurol. 2013 Jan
- Influence of gestational age on death and neurodevelopmental outcome in premature infants with severe intracranial hemorrhage.
- Goldstein RF, Cotten CM, Shankaran S, Gantz MG, Poole WK J Perinatol 2013 Jan 33 1 25-32
- Large conductance Ca2+-activated and voltage-activated K+ channels contribute to the rise and maintenance of estrogen-induced uterine vasodilation and maintenance of blood pressure.
- Rosenfeld CR, Roy T Endocrinology 2012 Dec 153 12 6012-20
- Renal function and systolic blood pressure in very-low-birth-weight infants 1-3 years of age.
- Frankfurt JA, Duncan AF, Heyne RJ, Rosenfeld CR Pediatr. Nephrol. 2012 Dec 27 12 2285-91
- Pregnancy increases myometrial artery myogenic tone via NOS- or COX-independent mechanisms.
- Eckman DM, Gupta R, Rosenfeld CR, Morgan TM, Charles SM, Mertz H, Moore LG Am. J. Physiol. Regul. Integr. Comp. Physiol. 2012 Aug 303 4 R368-75
- Empiric antifungal therapy and outcomes in extremely low birth weight infants with invasive candidiasis.
- Greenberg RG, Benjamin DK, Gantz MG, Cotten CM, Stoll BJ, Walsh MC, Sánchez PJ, Shankaran S, Das A, Higgins RD, Miller NA, Auten KJ, Walsh TJ, Laptook AR, Carlo WA, Kennedy KA, Finer NN, Duara S, Schibler K, Ehrenkranz RA, Van Meurs KP, Frantz ID, Phelps DL, Poindexter BB, Bell EF, O'Shea TM, Watterberg KL, Goldberg RN, Smith PB J. Pediatr. 2012 Aug 161 2 264-9.e2
- Are outcomes of extremely preterm infants improving? Impact of Bayley assessment on outcomes.
- Vohr BR, Stephens BE, Higgins RD, Bann CM, Hintz SR, Das A, Newman JE, Peralta-Carcelen M, Yolton K, Dusick AM, Evans PW, Goldstein RF, Ehrenkranz RA, Pappas A, Adams-Chapman I, Wilson-Costello DE, Bauer CR, Bodnar A, Heyne RJ, Vaucher YE, Dillard RG, Acarregui MJ, McGowan EC, Myers GJ, Fuller J J. Pediatr. 2012 Aug 161 2 222-8.e3
- Risk factors for post-neonatal intensive care unit discharge mortality among extremely low birth weight infants.
- De Jesus LC, Pappas A, Shankaran S, Kendrick D, Das A, Higgins RD, Bell EF, Stoll BJ, Laptook AR, Walsh MC J. Pediatr. 2012 Jul 161 1 70-4.e1-2
- Approach to infants born at 22 to 24 weeks' gestation: relationship to outcomes of more-mature infants.
- Smith PB, Ambalavanan N, Li L, Cotten CM, Laughon M, Walsh MC, Das A, Bell EF, Carlo WA, Stoll BJ, Shankaran S, Laptook AR, Higgins RD, Goldberg RN Pediatrics 2012 Jun 129 6 e1508-16
Regulation of the Placental Circulation. In Polin RA, Abman SH, Rowitch D, Benitz WE, eds. Fetal and Neonatal Physiology. 5th ed.
Rosenfeld CR. (2016). Philadelphia: Elsevier; 114-120.
Maternal Cardiovascular Alterations during Pregnancy. In Gluckman PS, Heymann MA, eds. Perinatal and Pediatric Pathophysiology: A Clinical Perspective.
Magness RR, Rosenfeld CR. (1993). London: Edward Arnold Publisher.
Eicosanoids and the Regulation of Uteroplacental Hemodynamics. In Mitchell MD, ed. Eicosanoids in Reproduction
Magness RR, Rosenfeld CR. (1990). CRC Press; 139-168.
Honors & Awards
- Albert Nelson Marquis Lifetime Achievement Award
Marquis Who's Who Publications Board (2018)
- Top Doctors
Castle Connolly Medical Ltd. (2014)
- Top Doctors
US News & World Report (2012)
- Student Teaching Award, Senior Acute Care Medicine
UT Southwestern Medical School (2008)
- Legends Award for Outstanding Service
Parkland Memorial Hospital (2007)
- SSPR Founders Award
Recognition for research contributing to improving child health, Southern Society of Pediatric Research (2005)
- Who's Who in America
- Associate Editor, Reproductive Sciences (JSGI)
Appointed to the initial Editorial Board; evaluating basic research (1993-2018)
- George L. MacGregor Professorship of Pediatrics
Recognition for research contributions in Perinatal Medicine (1993-2019)
- Associate Editor, Early Human Development
Responsible for all manuscripts in the Americas (1986)
- Perinatal Research Society
Recognition for contributions to studies in pregnancy and development (1981)
- American Pediatric Program Directors (2008-2010)
- American Heart Association (1999-2019)
- American Physiologic Society (1985-2019)
- American Pediatric Society (1983)
- Perinatal Research Society (1981)
- Society for Gynecologic Investigation (1978)
- Society for Pediatric Research (1977)
- American Academy of Pediatrics (1976)