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Liyuan Chen, Ph.D.

Liyuan Chen, Ph.D.

Titles and Appointments

Assistant Professor

School
Medical School
Department
Radiation Oncology
  • Biography

    Liyuan Chen, Ph.D., Assistant Professor in the Department of Radiation Oncology, earned her doctorate degree from Hong Kong Baptist University. After graduation, she started a postdoctoral research fellow position at UT Southwestern Medical Center, followed by completion of her clinical training in UT Southwestern’s Medical Physics Residency Program where she served as chief resident during her second year.

    Dr. Chen's research interests include medical image reconstruction and processing, inverse treatment planning, and treatment outcome prediction.

  • Research Interest
    • Inverse treatment planning
    • Medical image processing: denoising, deblurring, segmentation, classification, and registration
    • Medical image reconstruction
    • Treatment outcome prediction
  • Publications
    Impact of daily adaptive head and neck radiotherapy on toxicity and quality of life: Results of the DARTBOARD phase II randomized trial
    Sher DJ, Avkshtol V, Lin M, Wang J, Chen L, Liao CY, Hughes RS, Domal S, Ahn CW, Moon DH Journal of the National Cancer Institute 2025 Dec 117 2488-2494
    Dosimetric Advantages of Online Adaptive Radiation Therapy for Head and Neck Squamous Cell Carcinoma: Results From a Prospective Registry Study
    Shi JJ, Meduri K, Liao CY, Moon DH, Avkshtol V, Parsons D, Zhong X, Chen L, Lin MH, Sher DJ International Journal of Radiation Oncology Biology Physics 2025 Jul 122 917-925
    Assessment of cardiac radiation dose in the Co-60 prone-based stereotactic partial breast irradiation using distance metrics
    Kwon YS, Parsons DD, Arbab M, Wandrey N, Yarlagadda P, Stojadinovic S, Lu W, Alluri P, Li XD, Chiu T, Lin M, Chen L, Kim DW, Gonzalez YA, Gu X, Zhang Y, Timmerman R, Rahimi AS Frontiers in Oncology 2025 15
    Early Detection of Residual/Recurrent Lung Malignancies on Post-Radiation FDG PET/CT
    Chen L, Lowe A, Wang J Algorithms 2024 Oct 17
    Zero-Shot Medical Image Translation via Frequency-Guided Diffusion Models
    Li Y, Shao HC, Liang X, Chen L, Li R, Jiang S, Wang J, Zhang Y IEEE Transactions on Medical Imaging 2024 Mar 43 980-993
    Joint Vestibular Schwannoma Enlargement Prediction and Segmentation Using a Deep Multi-task Model
    Wang K, George-Jones NA, Chen L, Hunter JB, Wang J Laryngoscope 2023 Oct 133 2754-2760
    Efficacy and Quality-of-Life Following Involved Nodal Radiotherapy for Head and Neck Squamous Cell Carcinoma: The INRT-AIR Phase II Clinical Trial
    Sher DJ, Moon DH, Vo D, Wang J, Chen L, Dohopolski M, Hughes R, Sumer BD, Ahn C, Avkshtol V Clinical Cancer Research 2023 Sep 29 3284-3291
    ARMO: automated and reliable multi-objective model for lymph node metastasis prediction in head and neck cancer
    Zhou Z, Chen L, Dohopolski M, Sher D, Wang J Physics in medicine and biology 2023 May 68
    Clinical experience on patient-specific quality assurance for CBCT-based online adaptive treatment plan
    Shen C, Chen L, Zhong X, Gonzalez Y, Visak J, Meng B, Inam E, Parsons D, Godley A, Jiang S, Cai B, Lin MH Journal of applied clinical medical physics 2023 Apr 24
    Case study: Lymph node malignancy classification for head and neck cancer radiation therapy
    Wang J, Chen L, Dohopolski M, Sher D 2023 Jan 401-423
  • Honors & Awards
    • Interdisciplinary Contest In Modeling – Meritorious Winner
      (2011)
  • Professional Associations/Affiliations
    • American Association of Physicists in Medicine (AAPM) (2021)
    • American Society of Radiation Oncology (ASTRO) (2021)