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Liyuan Chen, Ph.D.

Liyuan Chen, Ph.D.

Titles and Appointments

Assistant Professor

Schools
Medical School
Departments
Radiation Oncology
  • Biography

    Liyuan Chen, Ph.D., Assistant Professor in the Department of Radiation Oncology, earned her doctorate degree from Hong Kong Baptist University. After graduation, she started a postdoctoral research fellow position at UT Southwestern Medical Center, followed by completion of her clinical training in UT Southwestern’s Medical Physics Residency Program where she served as chief resident during her second year.

    Dr. Chen's research interests include medical image reconstruction and processing, inverse treatment planning, and treatment outcome prediction.

  • Research Interest
    • Inverse treatment planning
    • Medical image processing: denoising, deblurring, segmentation, classification, and registration
    • Medical image reconstruction
    • Treatment outcome prediction
  • Publications
    Involved nodal versus elective neck radiotherapy (INVERT) for head and neck squamous cell carcinoma: a prospective phase II randomized controlled trial protocol
    Young S, Moon DH, Wang J, Chen L, Lin MH, Zhu L, Ahn CW, Hughes R, Sher DJ BMC Cancer 2026 Dec 26
    A Simulation-Free Radiation Therapy Workflow Using Synthetic Computed Tomography Generated from Diagnostic Magnetic Resonance Imaging for Personalized Hippocampal-Sparing Whole-Brain Treatment
    Chen L, Iqbal Z, Lu W, Shen C, Dan T, Dohopolski M, Wardak Z, Sher D, Badiyan S, Timmerman R, Parsons D, Godley A, Jiang S, Lin MH Practical Radiation Oncology 2026 Jul 16 e332-e341
    Spatially aware radiomics integrating anatomical knowledge to improve lymph node malignancy prediction in head and neck cancer
    Chen L, Radpour S, Dohopolski M, Sher D, Wang J Journal of applied clinical medical physics 2026 Feb 27
    Artificial Intelligence in Clinical Radiation Oncology
    Nguyen D, Yang D, Shen C, Wang J, Chen L, Zhang Y, Deng J, Chen M, Lu W, Dohopolski M, Sher D, Jiang S 2026 Jan 168-182.e3
    Impact of daily adaptive head and neck radiotherapy on toxicity and quality of life: Results of the DARTBOARD phase II randomized trial
    Sher DJ, Avkshtol V, Lin MH, Wang J, Chen L, Liao CY, Hughes R, Domal S, Ahn C, Moon DH Journal of the National Cancer Institute 2025 Dec 117 2488-2494
    Dosimetric Advantages of Online Adaptive Radiation Therapy for Head and Neck Squamous Cell Carcinoma: Results From a Prospective Registry Study
    Shi JJ, Meduri K, Liao CY, Moon DH, Avkshtol V, Parsons D, Zhong X, Chen L, Lin MH, Sher DJ International Journal of Radiation Oncology Biology Physics 2025 Jul 122 917-925
    Assessment of cardiac radiation dose in the Co-60 prone-based stereotactic partial breast irradiation using distance metrics
    Kwon YS, Parsons D, Arbab M, Wandrey N, Yarlagadda P, Stojadinovic S, Lu W, Alluri P, Li X, Chiu T, Lin M, Chen L, Kim DW, Gonzalez Y, Gu X, Zhang Y, Timmerman R, Rahimi A Frontiers in Oncology 2025 15
    Early Detection of Residual/Recurrent Lung Malignancies on Post-Radiation FDG PET/CT
    Chen L, Lowe A, Wang J Algorithms 2024 Oct 17
    Zero-Shot Medical Image Translation via Frequency-Guided Diffusion Models
    Li Y, Shao HC, Liang X, Chen L, Li R, Jiang S, Wang J, Zhang Y IEEE Transactions on Medical Imaging 2024 Mar 43 980-993
    Joint Vestibular Schwannoma Enlargement Prediction and Segmentation Using a Deep Multi-task Model
    Wang K, George-Jones NA, Chen L, Hunter JB, Wang J Laryngoscope 2023 Oct 133 2754-2760
  • Honors & Awards
    • Interdisciplinary Contest In Modeling – Meritorious Winner
      (2011)
  • Professional Associations/Affiliations
    • American Association of Physicists in Medicine (AAPM) (2021)
    • American Society of Radiation Oncology (ASTRO) (2021)