James Richardson, D.V.M., Ph.D.

Graduate School

University of Guelph - Canada , Veterinary Medicine

Graduate School

Purdue University Main Campus (1982)

• analysis of murine phenotypes
• comparative pathology
• developmental biology

Featured Publications

Activation of cardiac gene expression by myocardin, a transcriptional cofactor for serum response factor

Wang,, D-Z., Chang,, P.S., Wang, Z., Sutherland, L., Richardson, J.A., Small, E., Krieg,, P.A., Olson, E.N. Cell 2001 105 851-862

Cytochrome c deficiency causes embryonic lethality and attenuates stress-induced apoptosis.

Li, K, Li Y., Shelton, J.M., Richardson, J.A., Wang, X., Williams, R.S. Cell 2000 101 389-399

Mice lacking the folic acid-binding protein Folbp1 are defective in early embryonic development.

Piedrahita, J.A., Oetama, B., Bennett, G.D., van Waes, J., Lacey, S.W., Kamen, B.A., Richardson, J.A., Lark, R.H., Finnell, R.H. Nature Genetics 1999 2 228-232

Narcolepsy in orexin knockout mice: Molecular genetics of sleep regulation.

Chemelli, R.M., Willie, J.T., Sinton, C.M., Elmquist, J.K., Scammell, T., Lee, C., Richardson, J.A., Williams, S.C., Xiong, Y., Fitch, T.E., Nakazato, M., Hammer, R.E., Saper, C.B., Yanagisawa, M. Cell 1999 98 437-451

Reeler/disabled-like disruption of neuronal migration in knockout mice lacking the VLDL receptor and ApoE receptor-2.

Trommsdorff, M., Gotthardt, M., Hiesberger, T., Shelton, J., Stockinger, W., Nimpf, J., Hammer, R.E., Richardson, J.A., Herz, J. Cell 1999 97 689-701

Twist regulates cytokine gene expression through a negative feedback loop that represses NF-kB activity.

Sosic, D., Richardson, J.A., Yu, K., Ornitz, D.M., Olson, E.N. Cell January 2003 112 169-180

Control of facial muscle development by MyoR and capsulin.

Lu, J., Bassel-Duby, R., Hawkins, A., Chang, P., Valdez, P., Wu, H., Gan, L., Shelton, J., Richardson, J.A., Olson, E.N. Science December 2002 298 2378-2381

Mitochondrial deficiency and cardiac sudden death in mice lacking the MEF2A transcription factor.

Naya, R.J., Black, B.L., Wu, H., Bassel-Duby, R., Richardson, J.A., Hill, J.A., Olson, E.N. Nature Medicine 2002 8 1303-1309

Modulation of cardiac growth and development by HOP, an unusual homeodomain protein.

Shin, C-H., Liu, Z-P., Passier, R., Zhang, C-L., Wang, D-Z., Harris, T.M., Yamagishi, H., Richardson, J.A., Childs, G., Olson, E.N. Cell 2002 110 725-735

Fibulin-5 is an elastin-binding protein essential for elastic fiber development in vivo.

Yanagisawa, H., Davis, E.C., Starcher, B.C., Ouchi, T., Yanagisawa, M., Richardson, J.A., Olson, E.N. Nature 2002 415 168-71

• Piper Professor
  (2008)
• Outstanding Teacher
  (2006)
• Outstanding Teacher
  (2003)
• Outstanding Teacher
  (2001)
• Outstanding Teacher
  (1998)

• American Association for Advancement of Science
• American Veterinary Medical Association
• U T Southwestern Academy of Teachers
• United States and Canadian Academy of Pathology
• University of Texas Academy of Health Science Education