Joseph A. Maldjian, MD, is Professor of Radiology at UT Southwestern, and serves as Chief of the Neuroradiology Division and Director of the Advanced Neuroscience Imaging Research Lab. His clinical interests involve bringing novel imaging methodologies and advanced analysis methods into the clinical setting.
What I really appreciate about neuroradiology at UT Southwestern is the perfect partnering of clinical and research excellence.
After receiving his bachelor’s degree in biochemistry from Princeton University, Dr. Maldjian earned his medical degree from the University of Medicine and Dentistry of New Jersey in Newark. He completed his residency training in diagnostic radiology at Mount Sinai Medical Center in New York, and then received advanced training in neuroradiology through a two-year fellowship at the University of Pennsylvania School of Medicine in Philadelphia.
Before joining the faculty at UT Southwestern, Dr. Maldjian served as a Professor of Radiology and Biomedical Engineering at Wake Forest University School of Medicine in Winston-Salem, North Carolina. Prior to that, he held faculty appointments at the Hospital of the University of Pennsylvania, and at New Jersey Medical School.
Investigating traumatic brain injuries
Dr. Maldjian’s research team has been instrumental in bringing arterial spin-labeling (ASL) into routine clinical practice. This noninvasive method “tags” arterial blood water through a process of magnetic inversion, making it possible for a magnetic resonance imaging (MRI) scanner to detect the “magnetized” blood flowing through brain tissue. He has also developed fully automated means for processing, archiving and analyzing these images, as well as images obtained using functional MRI, diffusion tensor imaging, positron emission tomography, and magnetoencephalography (MEG). Dr. Maldjian’s research lab maintains a data processing resource that can handle large amounts of neuroimaging data and provide an interface to an array of commonly used software platforms.
The main focus of Dr. Maldjian’s research is sports-related, mild traumatic brain injury. He is currently one of only a few radiologists in the nation to serve as principal investigator on three active National Institutes of Health (NIH)-funded R01 studies. Dr. Maldjian and his collaborators are studying the effects of sub-concussive impacts on youth and high school football players by obtaining MRI, MEG, cognitive measures and detailed head impact data from sensors embedded in players’ helmets.
He is also investigating whether genetic and racial factors related to diabetes might lead to changes in the brain structure and function in African-Americans.
Dr. Maldjian is an active member of numerous national and international societies, including the International Society for Magnetic Resonance in Medicine, American Society of Neuroradiology, American Society for Functional Neuroradiology, American College of Radiology, American Board of Radiology, and the Radiological Society of North America.
Robust editorial activity
In addition to authoring more than 125 peer-reviewed publications and over 15 additions to textbooks, Dr. Maldjian is a reviewer for multiple academic journals, including Radiology, Neuroradiology, Neurology, Neuroimage, Clinical Neuroradiology, American Journal of Neuroradiology, Annals of Biomedical Engineering, Neuroinformatics, and Journal of Computer Assisted Tomography. He also serves as a charter member of the NIH Biomedical Imaging Technology Study Section A.
Dr. Maldjian is a trained classical pianist who spends much of his free time with his wife designing, testing, and optimizing novel reward systems to get their four young children to practice the instrument.
- Medical School
- University of Medicine and Dentistry - New Jersey Medical School (1988)
- St Barnabas Medical Center (1989), Internal Medicine
- Icahn School of Medicine at Mount Sinai (1993), Diagnostic Radiology
- Hospital of the University of Pennsylvania (1995), Neuroradiology
- Advanced Neuroimaging Applications
- Neuroimaging Analysis Pipelines
- Resting State Magnetoencephalography (MEG) Analyses
- Sports-Related Mild Traumatic Brain Injury
- An adaptive staircase procedure for the E-Prime programming environment.
- Hairston WD, Maldjian JA Comput Methods Programs Biomed 2009 Jan 93 1 104-8
- Aging and the interaction of sensory cortical function and structure.
- Peiffer AM, Hugenschmidt CE, Maldjian JA, Casanova R, Srikanth R, Hayasaka S, Burdette JH, Kraft RA, Laurienti PJ Hum Brain Mapp 2009 Jan 30 1 228-40
- Contrast-enhanced MR imaging of brain lesions: a large-scale intraindividual crossover comparison of gadobenate dimeglumine versus gadodiamide.
- Rowley HA, Scialfa G, Gao PY, Maldjian JA, Hassell D, Kuhn MJ, Wippold FJ, Gallucci M, Bowen BC, Schmalfuss IM, Ruscalleda J, Bastianello S, Colosimo C AJNR Am J Neuroradiol 2008 Oct 29 9 1684-91
- Migraine associated cerebral hyperperfusion with arterial spin-labeled MR imaging.
- Pollock JM, Deibler AR, Burdette JH, Kraft RA, Tan H, Evans AB, Maldjian JA AJNR Am J Neuroradiol 2008 Sep 29 8 1494-7
- Arterial spin-labeling in routine clinical practice, part 3: hyperperfusion patterns.
- Deibler AR, Pollock JM, Kraft RA, Tan H, Burdette JH, Maldjian JA AJNR Am J Neuroradiol 2008 Sep 29 8 1428-35
- Anoxic injury-associated cerebral hyperperfusion identified with arterial spin-labeled MR imaging.
- Pollock JM, Whitlow CT, Deibler AR, Tan H, Burdette JH, Kraft RA, Maldjian JA AJNR Am J Neuroradiol 2008 Aug 29 7 1302-7
- Arterial spin-labeling in routine clinical practice, part 1: technique and artifacts.
- Deibler AR, Pollock JM, Kraft RA, Tan H, Burdette JH, Maldjian JA AJNR Am J Neuroradiol 2008 Aug 29 7 1228-34
- Arterial spin-labeling in routine clinical practice, part 2: hypoperfusion patterns.
- Deibler AR, Pollock JM, Kraft RA, Tan H, Burdette JH, Maldjian JA AJNR Am J Neuroradiol 2008 Aug 29 7 1235-41
- Clinical implementation of spin-tag perfusion magnetic resonance imaging.
- Maldjian JA, Laurienti PJ, Burdette JH, Kraft RA J Comput Assist Tomogr 2008 May-Jun 32 3 403-6
- The impact of temporal regularization on estimates of the BOLD hemodynamic response function: a comparative analysis.
- Casanova R, Ryali S, Serences J, Yang L, Kraft R, Laurienti PJ, Maldjian JA Neuroimage 2008 May 40 4 1606-18
Honors & Awards
- Best Paper Trainee (Co-Author)
American Society of Neuroradiology (2014)
- Graduate Design and Research Award (Co-Author)
Biomedical Engineering Society (2014)
- Best Poster (Co-Author)
American Society of Functional Neuroradiology (2012)
- Outstanding Teacher
International Society for Magnetic Resonance in Medicine (2009)
- Derek Harwood-Nash Award (co-author), Outstanding Presentation Award in Pediatric Neuroradiology
American Society of Neuroradiology (2008)
- Best Doctors in America
U.S. News & World Report (2005-2015)
- Rennick Award (co-author)
International Neuropsychological Society (2001)
- American Roentgen Ray Society Scholar
American Roentgen Ray Society (1999)
- Sanofi-Winthrop Fellow in Neuroradiology
Hospital of the University of Pennsylvania (1993)
- Chief Resident, Department of Radiology
Mount Sinai Medical Center, New York (1992)
- Magna Cum Laude, Biochemistry
Princeton University (1984)
- American Board of Radiology
- American College of Radiology
- American Society for Functional Neuroradiology
- American Society of Neuroradiology
- International Society for Magnetic Resonance in Medicine
- Radiological Society of North America