Joseph A. Maldjian, MD, is Professor of Radiology at UT Southwestern, and serves as Chief of the Neuroradiology Division and Director of the Advanced Neuroscience Imaging Research Lab. His clinical interests involve bringing novel imaging methodologies and advanced analysis methods into the clinical setting.
What I really appreciate about neuroradiology at UT Southwestern is the perfect partnering of clinical and research excellence.
After receiving his bachelor’s degree in biochemistry from Princeton University, Dr. Maldjian earned his medical degree from the University of Medicine and Dentistry of New Jersey in Newark. He completed his residency training in diagnostic radiology at Mount Sinai Medical Center in New York, and then received advanced training in neuroradiology through a two-year fellowship at the University of Pennsylvania School of Medicine in Philadelphia.
Before joining the faculty at UT Southwestern, Dr. Maldjian served as a Professor of Radiology and Biomedical Engineering at Wake Forest University School of Medicine in Winston-Salem, North Carolina. Prior to that, he held faculty appointments at the Hospital of the University of Pennsylvania, and at New Jersey Medical School.
Investigating traumatic brain injuries
Dr. Maldjian’s research team has been instrumental in bringing arterial spin-labeling (ASL) into routine clinical practice. This noninvasive method “tags” arterial blood water through a process of magnetic inversion, making it possible for a magnetic resonance imaging (MRI) scanner to detect the “magnetized” blood flowing through brain tissue. He has also developed fully automated means for processing, archiving and analyzing these images, as well as images obtained using functional MRI, diffusion tensor imaging, positron emission tomography, and magnetoencephalography (MEG). Dr. Maldjian’s research lab maintains a data processing resource that can handle large amounts of neuroimaging data and provide an interface to an array of commonly used software platforms.
The main focus of Dr. Maldjian’s research is sports-related, mild traumatic brain injury. He is currently one of only a few radiologists in the nation to serve as principal investigator on three active National Institutes of Health (NIH)-funded R01 studies. Dr. Maldjian and his collaborators are studying the effects of sub-concussive impacts on youth and high school football players by obtaining MRI, MEG, cognitive measures and detailed head impact data from sensors embedded in players’ helmets.
He is also investigating whether genetic and racial factors related to diabetes might lead to changes in the brain structure and function in African-Americans.
Dr. Maldjian is an active member of numerous national and international societies, including the International Society for Magnetic Resonance in Medicine, American Society of Neuroradiology, American Society for Functional Neuroradiology, American College of Radiology, American Board of Radiology, and the Radiological Society of North America.
Robust editorial activity
In addition to authoring more than 125 peer-reviewed publications and over 15 additions to textbooks, Dr. Maldjian is a reviewer for multiple academic journals, including Radiology, Neuroradiology, Neurology, Neuroimage, Clinical Neuroradiology, American Journal of Neuroradiology, Annals of Biomedical Engineering, Neuroinformatics, and Journal of Computer Assisted Tomography. He also serves as a charter member of the NIH Biomedical Imaging Technology Study Section A.
Dr. Maldjian is a trained classical pianist who spends much of his free time with his wife designing, testing, and optimizing novel reward systems to get their four young children to practice the instrument.
- Medical School
- University of Medicine and Dentistry - New Jersey Medical School (1988)
- St Barnabas Medical Center (1989), Internal Medicine
- Icahn School of Medicine at Mount Sinai (1993), Diagnostic Radiology
- Hospital of the University of Pennsylvania (1995), Neuroradiology
- Advanced Neuroimaging Applications
- Neuroimaging Analysis Pipelines
- Resting State Magnetoencephalography (MEG) Analyses
- Sports-Related Mild Traumatic Brain Injury
- Effects of Type 2 Diabetes on Brain Structure and Cognitive Function: African American-Diabetes Heart Study MIND.
- Whitlow CT, Sink KM, Divers J, Smith SC, Xu J, Palmer ND, Hugenschmidt CE, Williamson JD, Bowden DW, Freedman BI, Maldjian JA AJNR Am J Neuroradiol 2015 Jul
- Relationships between Cognitive Performance, Neuroimaging and Vascular Disease: The DHS-MIND Study.
- Hsu FC, Raffield LM, Hugenschmidt CE, Cox A, Xu J, Carr JJ, Freedman BI, Maldjian JA, Williamson JD, Bowden DW Neuroepidemiology 2015 Jul 45 1 1-11
- Multi-TI Arterial Spin Labeling MRI with Variable TR and Bolus Duration for Cerebral Blood Flow and Arterial Transit Time Mapping.
- Johnston ME, Lu K, Maldjian JA, Jung Y IEEE Trans Med Imaging 2015 Jun 34 6 1392-402
- Heritability and genetic association analysis of neuroimaging measures in the Diabetes Heart Study.
- Raffield LM, Cox AJ, Hugenschmidt CE, Freedman BI, Langefeld CD, Williamson JD, Hsu FC, Maldjian JA, Bowden DW Neurobiol. Aging 2015 Mar 36 3 1602.e7-15
- Cerebral structural changes in diabetic kidney disease: African American-Diabetes Heart Study MIND.
- Sink KM, Divers J, Whitlow CT, Palmer ND, Smith SC, Xu J, Hugenschmidt CE, Wagner BC, Williamson JD, Bowden DW, Maldjian JA, Freedman BI Diabetes Care 2015 Feb 38 2 206-12
- Evaluation of morphological changes in the adult skull with age and sex.
- Urban JE, Weaver AA, Lillie EM, Maldjian JA, Whitlow CT, Stitzel JD J. Anat. 2014 Nov
- Vervet MRI atlas and label map for fully automated morphometric analyses.
- Maldjian JA, Daunais JB, Friedman DP, Whitlow CT Neuroinformatics 2014 Oct 12 4 543-50
- Functional neuroimaging of dressing-related skills.
- Wittenberg GF, Lovelace CT, Foster DJ, Maldjian JA Brain Imaging Behav 2014 Sep 8 3 335-45
- Rapid-onset dystonia-parkinsonism associated with the I758S mutation of the ATP1A3 gene: a neuropathologic and neuroanatomical study of four siblings.
- Oblak AL, Hagen MC, Sweadner KJ, Haq I, Whitlow CT, Maldjian JA, Epperson F, Cook JF, Stacy M, Murrell JR, Ozelius LJ, Brashear A, Ghetti B Acta Neuropathol. 2014 Jul 128 1 81-98
- Kidney disease and cognitive function: African American-diabetes heart study MIND.
- Palmer ND, Sink KM, Smith SC, Xu J, Bowden DW, Hugenschmidt CE, Whitlow CT, Williamson JD, Maldjian JA, Divers J, Freedman BI Am. J. Nephrol. 2014 40 3 200-7
Honors & Awards
- Best Paper Trainee (Co-Author)
American Society of Neuroradiology (2014)
- Graduate Design and Research Award (Co-Author)
Biomedical Engineering Society (2014)
- Best Poster (Co-Author)
American Society of Functional Neuroradiology (2012)
- Outstanding Teacher
International Society for Magnetic Resonance in Medicine (2009)
- Derek Harwood-Nash Award (co-author), Outstanding Presentation Award in Pediatric Neuroradiology
American Society of Neuroradiology (2008)
- Best Doctors in America
U.S. News & World Report (2005-2015)
- Rennick Award (co-author)
International Neuropsychological Society (2001)
- American Roentgen Ray Society Scholar
American Roentgen Ray Society (1999)
- Sanofi-Winthrop Fellow in Neuroradiology
Hospital of the University of Pennsylvania (1993)
- Chief Resident, Department of Radiology
Mount Sinai Medical Center, New York (1992)
- Magna Cum Laude, Biochemistry
Princeton University (1984)
- American Board of Radiology
- American College of Radiology
- American Society for Functional Neuroradiology
- American Society of Neuroradiology
- International Society for Magnetic Resonance in Medicine
- Radiological Society of North America