Research Interest

  • Energetic regulation of liver metabolism
  • In Vivo and Ex Vivo utilization of stable isotope tracers
  • Metabolic Flux Analysis (MFA)
  • NMR and MS metabolomics

Publications

Featured Publications LegendFeatured Publications

Cytosolic Phosphoenolpyruvate Carboxykinase as a Cataplerotic Pathway in the Small Intestine.
Potts A, Uchida A, Deja S, Berglund ED, Kucejova B, Duarte JAG, Fu X, Browning JD, Magnuson MA, Burgess SC Am. J. Physiol. Gastrointest. Liver Physiol. 2018 Apr
The NQO1 bioactivatable drug, ß-lapachone, alters the redox state of NQO1+ pancreatic cancer cells, causing perturbation in central carbon metabolism.
Silvers MA, Deja S, Singh N, Egnatchik RA, Sudderth J, Luo X, Beg MS, Burgess SC, DeBerardinis RJ, Boothman DA, Merritt ME J. Biol. Chem. 2017 11 292 44 18203-18216
Serum and urine 1H NMR-based metabolomics in the diagnosis of selected thyroid diseases.
Wojtowicz W, Zabek A, Deja S, Dawiskiba T, Pawelka D, Glod M, Balcerzak W, Mlynarz P Sci Rep 2017 Aug 7 1 9108
Acetyl CoA Carboxylase Inhibition Reduces Hepatic Steatosis but Elevates Plasma Triglycerides in Mice and Humans: A Bedside to Bench Investigation.
Kim CW, Addy C, Kusunoki J, Anderson NN, Deja S, Fu X, Burgess SC, Li C, Ruddy M, Chakravarthy M, Previs S, Milstein S, Fitzgerald K, Kelley DE, Horton JD Cell Metab. 2017 Aug 26 2 394-406.e6
Application of (1)H NMR-based serum metabolomic studies for monitoring female patients with rheumatoid arthritis.
Zabek A, Swierkot J, Malak A, Zawadzka I, Deja S, Bogunia-Kubik K, Mlynarz P J Pharm Biomed Anal 2016 Jan 117 544-50
Metabolomics of Human Amniotic Fluid and Maternal Plasma during Normal Pregnancy.
Orczyk-Pawilowicz M, Jawien E, Deja S, Hirnle L, Zabek A, Mlynarz P PLoS ONE 2016 11 4 e0152740
1H NMR-based metabolic profiling for evaluating poppy seed rancidity and brewing.
Jawien E, Zabek A, Deja S, Lukaszewicz M, Mlynarz P Cell. Mol. Biol. Lett. 2015 Dec 20 5 757-72
Fusion of the 1H NMR data of serum, urine and exhaled breath condensate in order to discriminate chronic obstructive pulmonary disease and obstructive sleep apnea syndrome.
Zabek A, Stanimirova I, Deja S, Barg W, Kowal A, Korzeniewska A, Orczyk-Pawilowicz M, Baranowski D, Gdaniec Z, Jankowska R, Mlynarz P Metabolomics 2015 11 6 1563-1574
Metabolomics provide new insights on lung cancer staging and discrimination from chronic obstructive pulmonary disease.
Deja S, Porebska I, Kowal A, Zabek A, Barg W, Pawelczyk K, Stanimirova I, Daszykowski M, Korzeniewska A, Jankowska R, Mlynarz P J Pharm Biomed Anal 2014 Nov 100 369-380
Rapid determination of ibotenic acid and muscimol in human urine.
Deja S, Jawien E, Jasicka-Misiak I, Halama M, Wieczorek P, Kafarski P, Mlynarz P Magn Reson Chem 2014 Nov 52 11 711-4