Wenxin Zheng, M.D., Tenured Professor of Pathology, Obstetrics and Gynecology, American board certified pathologist, graduated from Shanghai Medical College Fudan University and trained at Columbia University, Cornell University, and Brown University Medical Centers in anatomic pathology and gynecologic pathology, Selected by US News and World Report multiple times as one of America's top pathologists, Dr. Zheng is an internationally recognized gynecologic pathologist with outstanding expertise in every aspect of gynecologic pathology.  Dr. Zheng’s main research contributions include endometrial serous carcinogenesis and precancerous lesion endometrial glandular dysplasia, cell origin of low-grade ovarian serous carcinoma, hormonal etiology of ovarian epithelial cancers, and tubal contribution of ovarian endometriosis and its associated ovarian cancers.  In addition to these, Dr. Zheng has created a novel approach called "One Stop Cervical Care (OSCC)" to diagnose and treat cervical precancers. 


Medical School
Shanghai Medical College of Fudan University (1982)
Hospital of Obstetrics and Gynecology (1983), Obstetrics & Gynecology
Hospital of Obstetrics and Gynecology (1986), Obstetrics & Gynecology
Columbia University Medical Center (1989), Molecular Reproduction
Cornell New York Presbyterian Hospital (1995), Pathology
Brown University Woman & Infant Hospital (1996), Gynecologic Pathology

Research Interest

  • Biomarkers to aid the diagnosis of gynecologic cancers
  • Cervical cancer: suitable model of cervical cancer screening, effective intervention, and prevention in developing countries.
  • Endometrial serous carcinoma: carcinogenesis, early detection and prevention
  • Ovarian cancer early detection and prevention
  • Tubal origin of ovarian endometriosis and its related cancer development
  • Tubal secretory cell biology


Featured Publications LegendFeatured Publications

Mechanism of progestin resistance in endometrial precancer/cancer through Nrf2-survivin pathway.
Fan R, Wang Y, Wang Y, Wei L, Zheng W Am J Transl Res 2017 9 3 1483-1491
Association between human papillomavirus type 16 E6 and E7 variants with subsequent persistent infection and recurrence of cervical high-grade squamous intraepithelial lesion after conization.
Zhang L, Yang B, Zhang A, Zhou A, Yuan J, Wang Y, Sun L, Cao H, Wang J, Zheng W J. Med. Virol. 2016 Apr
Overexpression and oncogenic function of HMGA2 in endometrial serous carcinogenesis.
Wei L, Liu X, Zhang W, Wei Y, Li Y, Zhang Q, Dong R, Kwon JS, Liu Z, Zheng W, Kong B Am J Cancer Res 2016 6 2 249-59
Ovarian serous carcinogenesis from tubal secretory cells.
Zhang W, Wei L, Li L, Yang B, Kong B, Yao G, Zheng W Histol. Histopathol. 2015 Jul 11645
Are clear cell carcinomas of the ovary and endometrium phenotypically identical? A proteomic analysis.
Fata CR, Seeley EH, Desouki MM, Du L, Gwin K, Hanley KZ, Hecht JL, Jarboe EA, Liang SX, Parkash V, Quick CM, Zheng W, Shyr Y, Caprioli RM, Fadare O Hum. Pathol. 2015 Jun
Primary sources of pelvic serous cancer in patients with endometrial intraepithelial carcinoma.
Jia L, Yuan Z, Wang Y, Cragun JM, Kong B, Zheng W Mod. Pathol. 2015 Jan 28 1 118-27
Tubal origin of ovarian endometriosis and clear cell and endometrioid carcinoma.
Wang Y, Mang M, Wang Y, Wang L, Klein R, Kong B, Zheng W Am J Cancer Res 2015 5 3 869-79
Flutamide and biomarkers in women at high risk for ovarian cancer: preclinical and clinical evidence.
Gruessner C, Gruessner A, Glaser K, AbuShahin N, Zhou Y, Laughren C, Wright H, Pinkerton S, Yi X, Stoffer J, Azodi M, Zheng W, Chambers SK Cancer Prev Res (Phila) 2014 Sep 7 9 896-905
Tubal origin of ovarian endometriosis.
Yuan Z, Wang L, Wang Y, Zhang T, Li L, Cragun JM, Chambers SK, Kong B, Zheng W Mod. Pathol. 2014 Aug 27 8 1154-62
IMP3 signatures of fallopian tube: a risk for pelvic serous cancers.
Wang Y, Wang Y, Li D, Li L, Zhang W, Yao G, Jiang Z, Zheng W J Hematol Oncol 2014 Jul 7 1 49


Featured Books Legend Featured Books